A5088028085- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- MicroRNA in disease regulation
- Ferroptosis and cancer prognosis
- Colorectal Cancer Surgical Treatments
- Circular RNAs in diseases
- Gastric Cancer Management and Outcomes
- Cancer-related gene regulation
- Colorectal Cancer Screening and Detection
- RNA Research and Splicing
- Cancer Mechanisms and Therapy
- Cancer Cells and Metastasis
- Radiomics and Machine Learning in Medical Imaging
- Cell Adhesion Molecules Research
- Cancer, Lipids, and Metabolism
- Colorectal and Anal Carcinomas
- AI in cancer detection
- RNA and protein synthesis mechanisms
- Cancer Immunotherapy and Biomarkers
First Affiliated Hospital of Wannan Medical College
2020-2025
Bengbu Medical College
2023
Wannan Medical College
2020-2022
Therapeutic resistance represents a bottleneck to treatment in advanced gastric cancer (GC). Ferroptosis is an iron-dependent form of non-apoptotic cell death and associated with anti-cancer therapeutic efficacy. Further investigations are required clarify the underlying mechanisms. Ferroptosis-resistant GC lines constructed. Dysregulated mRNAs between ferroptosis-resistant parental identified. The expression SOX13/SCAF1 manipulated where relevant biological molecular analyses performed....
To explore the safety and feasibility of modified approach for accessing superior mesenteric artery (SMA) in total laparoscopic radical resection right colon cancer. This single-center retrospective study included 107 patients who underwent cancer at The First Affiliated Hospital Wannan Medical College between August 2022 December 2023. 53 were SMA (modified group) 54 traditional (control group). control group cancer, following baseline pathological characteristics two groups compared:...
RAD54L is a prominent member of the SWI2/SNF2 protein family, primarily involved in homologous recombination repair (HRR) process, thereby playing pivotal role DNA double-strand breaks (DSBs). has been implicated development numerous tumors. Consequently, we aimed to investigate potential contribution pan-cancer.Various databases and analytical tools were employed for bioinformatics analysis. Moreover, vitro experiments conducted corroborate findings from analysis delve deeper into...
Tubby-like protein 3 (TULP3) is a member of the tubby family, has been related to development nervous system by gene knockout researches. Nevertheless, role TULP3 in gastric cancer not clear.Western blotting and real-time polymerase chain reaction (PCR) were employed for quantitative detection expression consecutive non-cancerous tissues, cells. The roles invasion, migration as well proliferation cell vivo vitro through utilizing colony formation, MTT, wound-healing, transwell mouse...
HEAT repeat-containing protein 1 (HEATR1) is related to the progression of several cancers. However, role HEATR1 in gastric cancer (GC) remains unknown. In present study, we aimed detect expression GC and identify its role. The expressions tissues were analyzed using Cancer Genome Atlas database by western blot analysis immunohistochemistry. Furthermore, cell lines MGC-803 AGS knocked down lentivirus-mediated shRNA. Cell proliferation apoptosis detected CCK-8 Caspase-Glo® 3/7 assays,...
Objective: To evaluate the feasibility and efficacy of modified reverse puncture device (mRPD) technique for transanal anastomosis in total laparoscopic colorectal resection with natural orifice specimen extraction surgery (NOSES).Methods: From August 2015 to September 2017, 34 patients underwent using mRPD place anvil abdominal cavity complete anastomosis.Results: All who NOSES were analyzed. The placement time was 5–14 min, an average 6.7 min. postoperative pain visual analogue scale (VAS)...
Abstract Purpose Tubby-like protein 3 (TULP3), a member of the tubby family, has been related to development nervous system by gene knockout researches. Nevertheless, regulatory mechanism and role TULP3 in gastric cancer are not clear. Current research is first probe into effect cancer. Methods Western blotting together with real time polymerase chain reaction (PCR) were employed for quantitative detection expression consecutive non-cancerous tissues, cells. Kaplan-Meier method along...