A5003822297- Atomic and Subatomic Physics Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Advanced MRI Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Congenital Heart Disease Studies
- Pleural and Pulmonary Diseases
- Respiratory Support and Mechanisms
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Medical Imaging and Pathology Studies
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Function and Risk Factors
- Medical Imaging Techniques and Applications
- Advanced NMR Techniques and Applications
- Tracheal and airway disorders
- Radiomics and Machine Learning in Medical Imaging
- Radiation Dose and Imaging
- Cardiac Valve Diseases and Treatments
- Ultrasound in Clinical Applications
- Immunodeficiency and Autoimmune Disorders
- Aortic Disease and Treatment Approaches
- Advanced X-ray and CT Imaging
- Cardiac Imaging and Diagnostics
- Cystic Fibrosis Research Advances
Ludwig-Maximilians-Universität München
2015-2024
German Center for Lung Research
2015-2024
LMU Klinikum
2015-2024
München Klinik
2018-2023
University Hospital Heidelberg
2008-2018
Heidelberg University
2006-2018
University Health Network
2011-2018
Toronto General Hospital
2012-2018
German Cancer Research Center
2006-2015
Boston Children's Hospital
2010-2015
Abstract Background Children with hepatoblastoma (HB) are at risk of sarcopenia due to immobility, chemotherapy, and malnutrition. We hypothesized that children HB have a low preoperative total psoas muscle area (tPMA), reflecting sarcopenia, which negatively impacts outcome. Procedure Retrospective study (1‐10 years) treated large university children's hospital from 2009 2018. tPMA was measured as the sum right left (PMA) intervertebral disc levels L3‐4 L4‐5. z ‐Scores were calculated using...
Background The majority of patients with childhood interstitial lung disease (chILD) caused by pathogenic variants in ATP binding cassette subfamily A member 3 (ABCA3) develop severe respiratory insufficiency within their first year life and succumb to if not transplanted. This register-based cohort study reviews ABCA3 who survived beyond the age 1 year. Method Over a 21-year period, diagnosed as chILD due deficiency were identified from Kids Lung Register database. 44 long-term clinical...
Background Children’s interstitial lung diseases (chILD) cover many rare entities, frequently not diagnosed or studied in detail. There is a great need for specialised advice and internationally agreed subclassification of entities collected register. Our objective was to implement an international management platform with independent multidisciplinary review cases at presentation long-term follow-up test if this would allow more accurate diagnosis. Also, quality reproducibility diagnostic...
In Germany, 10,000 cases of spontaneous pneumothorax are treated inpatient every year. The German Society for Thoracic Surgery, in co-operation with the Pulmonology, Radiological Society, and Internal Medicine has developed an S3 guideline on post-interventional moderated by Association Scientific Medical Societies.Based source British (2010) pneumothorax, a literature search was carried out from 2008 onwards, 1960 onwards. Evidence levels according to Oxford Center Evidence-Based (2011)...
Persistent tachypnea of infancy (PTI) is a specific clinical entity undefined etiology comprising the two diseases neuroendocrine cell hyperplasia (NEHI) and pulmonary interstitial glycogenosis. The outcome typical NEHI favorable. may be different for patients without presentation, thus lung biopsy to differentiate indicated.To determine whether infants with characteristic presentation computed tomographic (CT) imaging (referred as "usual PTI") have long-term findings similar those an...
Analysis of autoinflammatory and immunodeficiency disorders elucidates human immunity fosters the development targeted therapies. Oligoadenylate synthetase 1 is a type I interferon-induced, intracellular double-stranded RNA (dsRNA) sensor that generates 2'-5'-oligoadenylate to activate ribonuclease L (RNase L) as means antiviral defense. We identified four de novo heterozygous OAS1 gain-of-function variants in six patients with polymorphic characterized by recurrent fever, dermatitis,...
Computed tomography (CT) is the modality of choice for imaging airways. Volumetric data sets with isotropic spatial resolution based on multidetector thin-section CT overlapping reconstruction should be used. Chronic obstructive pulmonary disease and asthma are 2 most common entities that defined by airflow obstruction. The morphologic correlates airway changes dilation lumen, thickening wall, visibility small airways due to mucus or edema, air trapping, hypoxic vasoconstriction,...
Purpose Monitoring of regional lung function in interventional COPD trials requires alternative endpoints beyond global parameters such as FEV1. T1 relaxation times the might allow to draw conclusions on tissue composition, blood volume and oxygen fraction. The aim this study was evaluate potential value Magnetic resonance imaging (MRI) with native oxygen-enhanced mapping for assessment patients comparison contrast enhanced perfusion MRI. Materials Methods 20 (GOLD I-IV) underwent a coronal...
Hermansky-Pudlak syndrome (HPS), a hereditary multisystem disorder with oculocutaneous albinism, may be caused by mutations in one of at least 10 separate genes. The HPS-2 subtype is distinguished the presence neutropenia and knowledge its pulmonary phenotype children scarce. Six genetically proven presented to chILD-EU register between 2009 2017; data were collected systematically imaging studies scored blinded. Pulmonary symptoms including dyspnea, coughing, need for oxygen, clubbing...
Background: Sarcopenia describes a generalized loss of skeletal muscle mass, strength, or function. Determined by measuring the total psoas area (tPMA) on cross-sectional imaging, sarcopenia is an independent marker for poor post-surgical outcomes in adults and children. Children with cancer are at high risk due to immobility, chemotherapy, cachexia. We hypothesize that sarcopenic children neuroblastoma higher post-operative outcomes. Patients Methods: Retrospective analysis ages 1-15 years...
This information provided by the Thoracic Imaging Section of German Radiological Society is intended to give physicians recommendations on use thoracic imaging procedures in context current COVID-19 pandemic. It represents consensus authors based previous scientific knowledge and provide guidance for unified, structured CT reporting if pneumonia suspected. The presented correspond state at time print will be updated according results ongoing future studies. Key Points: Citation Format