A5039451688- Epigenetics and DNA Methylation
- Pluripotent Stem Cells Research
- Renal and related cancers
- Genomics and Chromatin Dynamics
- SARS-CoV-2 and COVID-19 Research
- Fungal and yeast genetics research
- SARS-CoV-2 detection and testing
- CRISPR and Genetic Engineering
- Cancer-related gene regulation
Centre for Genomic Regulation
2020-2024
Institute of Science and Technology
2020
We show that in S. cerevisiae the metabolic diauxic shift is associated with a H3 lysine 4 tri-methylation (H3K4me3) increase which involves significant fraction of transcriptionally induced genes are required for changes, suggesting role histone methylation their transcriptional regulation. H3K4me3 around start site correlates induction some these genes. Among methylation-induced IDP2 and ODC1, regulate nuclear availability α-ketoglutarate, which, as cofactor Jhd2 demethylase, regulates...
The COVID-19 pandemic has posed and is continuously posing enormous societal health challenges worldwide. research community mobilized to develop novel projects find a cure or vaccine, as well contribute mass testing, which been critical measure contain the infection in several countries. Through this article, we share our experiences learnings group of volunteers at Centre for Genomic Regulation (CRG) Barcelona, Spain. As members ORFEU project, an initiative by Government Catalonia achieve...