- Health, Medicine and Society
- Education, sociology, and vocational training
- Social Policies and Family
- Psychoanalysis and Psychopathology Research
- French Urban and Social Studies
- Cancer Genomics and Diagnostics
- Social Sciences and Governance
- Aging, Elder Care, and Social Issues
- Cancer Immunotherapy and Biomarkers
- Prostate Cancer Treatment and Research
- Mobile Health and mHealth Applications
- Lymphoma Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Radiopharmaceutical Chemistry and Applications
- Public Health and Social Inequalities
- Bladder and Urothelial Cancer Treatments
- Sarcoma Diagnosis and Treatment
- Statistical Methods in Clinical Trials
- Medication Adherence and Compliance
- Health Literacy and Information Accessibility
- Healthcare Systems and Practices
- Urinary and Genital Oncology Studies
- Viral-associated cancers and disorders
- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
Institut Curie
2023-2025
Centre Hospitalier Universitaire de Montpellier
2023
Université de Montpellier
2023
Université Paris Cité
2002-2022
Hôpital Saint-Louis
2019-2022
Assistance Publique – Hôpitaux de Paris
2014-2021
ASM International
2012-2019
Hôpital Cochin
2002-2017
Institut Gustave Roussy
2016-2017
Université Paris-Saclay
2017
Patients with advanced non-small-cell lung cancer (NSCLC) treated immune checkpoint blockers (ICBs) ultimately progress either rapidly (primary resistance) or after durable benefit (secondary resistance). The vaccine OSE2101 may invigorate antitumor-specific responses ICB failure. objective of ATALANTE-1 was to evaluate its efficacy and safety in these patients. a two-step open-label study the compared standard-of-care (SoC) chemotherapy (CT). human leukocyte antigen (HLA)-A2-positive NSCLC...
Mobile applications represent promising tools in management of chronic diseases, both for patients and healthcare professionals, especially oncology. Among the large number mobile health (mhealth) available stores, it could be difficult users to identify most relevant ones. This study evaluated business model scientific validation related oncology.A systematic review was performed over two major marketplaces. Purpose, validation, source funding were according description stores. Results...
Adipocytic tumors are the most common mesenchymal in soft tissues. Among them, a diagnostic challenge relies distinction between lipoma and atypical lipomatous tumor (ALT)/well differentiated liposarcoma (WDLPS), as both entities often undistinguishable not only from radiological point of view, but also at microscopic level particularly when dealing with small specimen. Thus, detection recurrent MDM2 amplifications may be criteria to discriminate malignant lipomas. In this study, we report...
The national reference network NETSARC+ provides remote access to specialized diagnosis and the Multidisciplinary Tumour Board (MTB) improve management survival of sarcoma patients in France. IGéAS research program aims assess potential this innovative organization address geographical inequalities cancer management. Using cohort built from nationwide database, individual, clinical, determinants 3-year overall France were analyzed. analysis was focused on diagnosed 2013 (n = 2281) ensure...
The purpose of our study was to evaluate the incidence Helicobacter pylori seropositivity in two different populations asymptomatic pregnant women from geographic origins during separate time periods. A retrospective consecutive sera obtained 169 and 302 1990 1999, respectively, carried out. global H. seroprevalences for 1999 were 21.3 21.5% (where P is nonsignificant), respectively. For both periods significantly higher non-French (66.6 50.6%) than French (18.7 11.2%) (P = 0.01 0.001,...
Background: The identification of activating mutations in specific genes led to the development targeted therapies for NSCLC. TKI directed against EGFR-mutations were first prove their major efficacy. Medical associations recommend use as and second-line metastatic treatments EGFR-mutated patients. Our objective was analyze survival patients treated beyond second line treatment. Methods: We performed a longitudinal, retrospective analytical study at APHP (Assistance Publique Hopitaux de...
e14025 Background: Progression-free survival ratio (PFSr) has been proposed as a direct evaluation of treatment benefit in advanced cancer patients, based on the hypothesis that natural history is accelerating and therefore successive lines treatments become less efficient over time. Consequently, PFS at line +2 (PFS2) expected to be shorter than +1 (PFS1), whereas PFS2/PFS1 > 1.3 might reflect benefit. However, this poorly documented, especially context early phase trials where...