Mehmet Mücahit Güncü

ORCID: 0000-0003-2004-8477
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Research Areas
  • Electrospun Nanofibers in Biomedical Applications
  • Wound Healing and Treatments
  • Silk-based biomaterials and applications
  • Antifungal resistance and susceptibility
  • Antimicrobial agents and applications
  • Antimicrobial Peptides and Activities
  • Dental materials and restorations
  • COVID-19 Clinical Research Studies
  • Periodontal Regeneration and Treatments
  • Antibiotic Resistance in Bacteria
  • Fungal Infections and Studies
  • Infectious Diseases and Mycology
  • Antibiotics Pharmacokinetics and Efficacy
  • SARS-CoV-2 detection and testing
  • Advanced Sensor and Energy Harvesting Materials
  • Medical and Biological Ozone Research
  • Seaweed-derived Bioactive Compounds
  • Ear Surgery and Otitis Media
  • COVID-19 diagnosis using AI
  • Phosphorus compounds and reactions
  • Anatomy and Medical Technology
  • Polymer Nanocomposite Synthesis and Irradiation
  • Antibiotic Use and Resistance
  • Synthetic Organic Chemistry Methods
  • 3D Printing in Biomedical Research

Marmara University
2020-2025

Maltepe University
2020

In this study, the main aim was to fabricate propolis (Ps)-containing wound dressing patches using 3D printing technology. Different combinations and structures of (Ps)-incorporated sodium alginate (SA) scaffolds were developed. The morphological studies showed that porosity developed optimized when 20% (v/v) Ps added solution. pore sizes decreased by increasing concentration up a certain level due its adhesive properties. mechanical, swelling-degradation (weight loss) behaviors, release...

10.3390/molecules25215082 article EN cc-by Molecules 2020-11-02

In this research, as an alternative to chemical and physical methods, environmentally cost-effective antimicrobial zinc oxide nanoparticles (ZnO NP) were produced by the green synthesis method. The current study focuses on production of ZnO NP starting from adequate precursor Zingiber officinale aqueous root extracts (ginger). was loaded into electrospun nanofibers at different concentrations for various tissue engineering applications such wound dressings. NPs NP-loaded examined Scanning...

10.3390/nano12173040 article EN cc-by Nanomaterials 2022-09-01

In this study, a dental membrane scaffold was fabricated using 3D printing technique, and the antimicrobial effect of pomegranate seed peel extract were investigated. For production scaffold, combination polyvinyl alcohol, starch, extracts used. The aim to cover damaged area aid in healing process. This can be achieved due high antioxidant content (PPE: PSE). Moreover, addition starch PPE: PSE improved biocompatibility their tested human gingival fibroblast (HGF) cells. into scaffolds...

10.3390/pharmaceutics15030737 article EN cc-by Pharmaceutics 2023-02-22

This study aimed to assess the prevalence of HDV (hepatitis delta virus), HCV C and HIV (human immunodeficiency virus) coinfections among HBsAg-positive patients determine severity liver fibrosis biochemical markers. Furthermore, sought evaluate noninvasive scores (APRI FIB4) in predicting disease with hepatitis B. A retrospective analysis 1434 chronic HBV admitted between January 2020 December 2024 was conducted at Sincan Tertiary Hospital. The positivity rates following antibodies were...

10.3390/v17040568 article EN cc-by Viruses 2025-04-15

Abstract 3D‐printed scaffolds can better mimic the function of human skin, both biologically and mechanically. Within scope this study, effect addition different amounts (10, 15, 20 mg) gentamicin sulfate (GS) to a 10 mL solution natural synthetic polymers is investigated. Sodium alginate (SA), gelatin‐methacryloyl (GelMA), polyvinyl alcohol (PVA) are chosen as bioactive materials. The surface morphology pore structures visualized by scanning electron microscopy (SEM). According results, it...

10.1002/mame.202300151 article EN cc-by Macromolecular Materials and Engineering 2023-10-24

Abstract Bacterial infection is a global problem, especially resistance acquired by bacteria against to antibiotics; there urgent need for the development of antibiotics. Here, we proposed dendron‐grafted polymers via ring opening metathesis polymerization (ROMP) featuring different with tailored hydrophobicity/hydrophilicity and cationic charges. Dendritic oxanorbornene derivatives were synthesized having two six carbon linkers their corresponding random block copolymers prepared pendant...

10.1002/pol.20190194 article EN Journal of Polymer Science 2020-02-10

In this study, phosphonium salt-bearing polynorbornenes were synthesized using five different aromatic side chains (triphenylphosphonium, trifluorophenyl phosphonium, trichlorophenyl tri(p-tolyl)phosphonium, and cyclohexyldiphenyl phosphonium) via ring-opening metathesis polymerization (ROMP). The biological activities of these polymers determined by their minimal inhibitory concentration (MIC) minimum bactericidal (MBC) against Escherichia coli Staphylococcus aureus, additionally,...

10.1021/acsapm.1c01234 article EN ACS Applied Polymer Materials 2021-11-26

The rapid and reliable diagnosis of anaerobic bacteria constitutes one the key procedures in clinical microbiology. Automatic jar gassing systems are commonly used laboratory instruments for this purpose. most critical factors affecting cultivation performance these level residual oxygen remaining reaction rate determined by Pd/Al

10.3390/bioengineering11111068 article EN cc-by Bioengineering 2024-10-25

Abstract Periodontal diseases, if untreated, can cause gum recession and tooth root exposure, resulting in infection irreversible damage. Traditional treatments using autologous grafts are painful often result postoperative complications. Scaffolds offer a less invasive alternative, promoting cell proliferation healing without additional surgery, thus enhancing comfort for patients doctors. This study developed Chitosan (Chit)/Collagen (Col) film surfaces drug‐loaded Polyvinyl Alcohol...

10.1002/mabi.202400331 article EN Macromolecular Bioscience 2024-11-18

Objective: It was aimed to identify the contaminant and determine alternative disinfectant detection in microbial growth
 observed various parts of cadaver stored formalin tank dissection laboratory Marmara University Anatomy
 Department. We also performed a literature review this unusual pathogen.
 Materials Methods: Swab samples were inoculated on agar mediums. After incubation, matrix-assisted laser desorption ionizationtime
 flight mass spectrometry (MALDI-TOF MS)...

10.5472/marumj.1244383 article EN Marmara medical journal 2023-01-30

Background The number of COVID-19 cases has been decreasing recently, and the restrictions are waived in many countries. data about vaccine efficacy essential to be prepared for future even if pandemic ends disease becomes endemic. Aims aim this study was define demographic laboratory severity among vaccinated who were hospitalized. Study Design This is a retrospective cohort study. Methods SARS-CoV-2 polymerase chain reaction–positive patients fully (2 doses vaccines 3 vaccines) had...

10.1097/ipc.0000000000001251 article EN Infectious Diseases in Clinical Practice 2023-04-06

Abstract Background: A rapid and reliable diagnostic test is needed to reduce mortality through early diagnosis of invasive aspergillosis (IA) in patients with hematological malignancies. Objective: To evaluate the efficacy serum bronchoalveolar lavage (BAL) Aspergillus galactomannan lateral flow assay (GM-LFA) IA determine correlation GM-LFA GM enzyme immunoassay (GM-EIA) Methods: In this prospective multicenter study, we used BAL fluid samples from malignancies suspected performed GM-EIA....

10.21203/rs.3.rs-2782725/v1 preprint EN cc-by Research Square (Research Square) 2023-04-11

We aimed to analyze the distribution of respiratory pathogens(RP) detected by a multiplex PCR-based method (BioFire Diagnostics, USA) among patients with suspected tract infections (RTI) and evaluate demographic, clinical radiological characteristics infected individuals . RP were in 1621/6376 (25.4%) samples years 2018-2020. Rhinovirus/enterovirus (RV/EV) most commonly pathogens (38.1%) followed influenza A B viruses (21%) parainfluenza virus (PIV) (9.5%). Single pathogen was 1361 (84%)...

10.22354/24223794.1127 article EN Infectio 2023-04-23
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