A5002912396- Electrospun Nanofibers in Biomedical Applications
- Corneal Surgery and Treatments
- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Ocular Surface and Contact Lens
- Wound Healing and Treatments
- Bee Products Chemical Analysis
- Silk-based biomaterials and applications
- biodegradable polymer synthesis and properties
- Tissue Engineering and Regenerative Medicine
- Electrohydrodynamics and Fluid Dynamics
- Additive Manufacturing and 3D Printing Technologies
- Advancements in Transdermal Drug Delivery
- Advanced Drug Delivery Systems
- Ear Surgery and Otitis Media
- Ocular Infections and Treatments
- Advanced Cellulose Research Studies
- SARS-CoV-2 detection and testing
- Botanical Research and Applications
- Mass Spectrometry Techniques and Applications
- Orthopaedic implants and arthroplasty
- Nasal Surgery and Airway Studies
- Conducting polymers and applications
- Polymer Nanocomposite Synthesis and Irradiation
- Biosensors and Analytical Detection
Marmara University
2020-2025
Bülent Ecevit University
2019
Microneedles (MNs) are micrometer-sized arrays that can penetrate the skin in a minimally invasive manner; these devices offer tremendous potential for transdermal delivery of therapeutic molecules. Although there many conventional techniques manufacturing MNs, most them complicated and only fabricate MNs with specific geometries, which restricts ability to adjust performance MNs. Herein, we present fabrication gelatin methacryloyl (GelMA) MN using vat photopolymerization 3D printing...
In this research, polyvinyl-alcohol (PVA)/gelatin (GEL)/propolis (Ps) biocompatible nanofiber patches were fabricated via electrospinning technique. The controlled release of Propolis, surface wettability behaviors, antimicrobial activities against the S. aureus and P. aeruginosa, biocompatibility properties with mesenchymal stem cells (MSCs) investigated in detail. By adding 0.5, 1, 3 wt.% GEL into 13 PVA, morphological mechanical results suggested that PVA/0.5 patch can be an ideal matrix...
Parkinson’s disease, the second most common neurodegenerative disease in world, develops due to decreased dopamine levels basal ganglia. Levodopa, a precursor used treatment of can be as drug delivery system. This study presents an approach use 3D-printed levodopa-loaded neural tissue scaffolds produced with polylactic acid (PLA) and chitosan (CS) for disease. Surface morphology pore sizes were examined by scanning electron microscopy (SEM). Average 100–200 µm found ideal engineering...
Abstract In this study, polyvinyl alcohol (PVA), gelatin (GEL) and gentamicin (GEN) were used 13PVA/0.5GEL/GEN nanofibers fabricated with the electrospinning method. These crosslinked chemically glutaraldehyde (GA) at different time intervals (2, 3, 4, 5, 5.5 6 h) to observe crosslinking effect on properties of nanofibers. Morphological analysis reported that as increased, nanofiber diameters also increased from 369.26 nm (non‐crosslinked) 447.72 (6 h/crosslinking), respectively. The thermal...
In this research, as an alternative to chemical and physical methods, environmentally cost-effective antimicrobial zinc oxide nanoparticles (ZnO NP) were produced by the green synthesis method. The current study focuses on production of ZnO NP starting from adequate precursor Zingiber officinale aqueous root extracts (ginger). was loaded into electrospun nanofibers at different concentrations for various tissue engineering applications such wound dressings. NPs NP-loaded examined Scanning...
This study introduces novel chitosan (CS) and polyethylene oxide (PEO) copolymers reinforced with bacterial cellulose (BC) to fabricate nanofibers using the electrospinning method. SEM analysis confirmed uniform nanofiber formation, CS/PEO/BC (~240 nm) exhibiting a larger diameter than CS/PEO ones (~190 nm). FTIR spectroscopy BC integration, while Differential scanning calorimetry indicated minimal impact on glass transition temperature. Notably, as compared nanofibers, demonstrated superior...
Polymeric microparticles with controlled morphologies and sizes are being studied by researchers in many applications, such as for drug release, healthcare cosmetics. Herein, spherical porous polymeric of different electrospray technique have been developed a viable alternative. In this work, polylactic acid (PLA) shape morphology were successfully produced via an single step. Molecular interactions between the components effect parameters, varying solvent compositions, flow rates voltage on...
In this study, two-layer poly(vinyl alcohol)/gelatin (PVA/GEL) nanofiber patches containing cinnamaldehyde (CA) in the first layer and gentamicin (GEN) second were produced by electrospinning method. The morphology, chemical structures, thermal temperatures of pure (PVA/GEL), CA-loaded (PVA/GEL/CA), GEN-loaded (PVA/GEL/GEN), combined drug-loaded (PVA/GEL/CA/GEN) determined scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, differential calorimetry, respectively....
Abstract Corneal ulcer, which is brought on by a breach in the epithelial barrier, dangerous infection of avascular corneal stroma. New treatment strategies are needed, suppressing aggressive nature disease and including combination different drugs. In this study, vancomycin (VAN) fluconazole (FLU) dual‐drug loaded dual‐layered polyvinyl alcohol gelatin (PVA/GEL) nanofibrous patches produced electrospinning. Scanning electron microscopy (SEM) images show smooth surfaces obtained for both...
Postoperative infection in orthopaedic and trauma surgery is one of the most feared complications. Recently, high prevalence multidrug-resistant bacteria has made antibiotic treatment ineffective; thus novel non-antibiotic alternative approaches to this problem are urgently needed. Based on these expectations, work, order enhance cytocompatibility antibacterial performances poly (methyl methacrylate (PMMA) beta-tricalcium phosphate (β-TCP) bone cements were impregnated with polystyrene...
Abstract Chronic skin wounds pose a global clinical challenge, necessitating effective treatment strategies. This study explores the potential of 3D printed Poly Lactic Acid (PLA) scaffolds, enhanced with Whey Protein Concentrate (WPC) at varying concentrations (25, 35, and 50% wt), for wound healing applications. PLA’s biocompatibility, biodegradability, thermal stability make it an ideal material medical The addition WPC aims to mimic skin’s extracellular matrix enhance bioactivity PLA...