A5069208386- Bone Tissue Engineering Materials
- Additive Manufacturing and 3D Printing Technologies
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- biodegradable polymer synthesis and properties
- Calcium Carbonate Crystallization and Inhibition
- Dental Implant Techniques and Outcomes
- Tendon Structure and Treatment
- Dental materials and restorations
- Cellular and Composite Structures
- Tissue Engineering and Regenerative Medicine
- Corneal Surgery and Treatments
- Advanced Drug Delivery Systems
- Natural Fiber Reinforced Composites
- Marine Biology and Environmental Chemistry
- Aerogels and thermal insulation
- Electrohydrodynamics and Fluid Dynamics
- Wound Healing and Treatments
- Laser-Ablation Synthesis of Nanoparticles
- Retinal Diseases and Treatments
- Fiber-reinforced polymer composites
- Sports injuries and prevention
- Orthopaedic implants and arthroplasty
- Polymer composites and self-healing
- Ocular Surface and Contact Lens
Warsaw University of Technology
2014-2025
Materials Science & Engineering
2022-2024
Silesian University of Technology
2007
Fiber-based approaches hold great promise for tendon tissue engineering enabling the possibility of manufacturing aligned hydrogel filaments that can guide collagen fiber orientation, thereby providing a biomimetic micro-environment cell attachment, migration, and proliferation. In this study, 3D system composed cell-laden, highly yarns is designed obtained via wet spinning in order to reproduce morphology structure fascicles. A bioink alginate gelatin methacryloyl (GelMA) optimized loaded...
One promising strategy to reconstruct osteochondral defects relies on 3D bioprinted three-zonal structures comprised of hyaline cartilage, calcified and subchondral bone. So far, several studies have pursued the regeneration either cartilage or bone in vitro while-despite its key role region-only few them targeted layer. In this work, we present a biomimetic hydrogel scaffold containing β-tricalcium phosphate (TCP) for engineering through co-axial needle system implemented extrusion-based...
Abstract Injection of cell‐laden scaffolds in the form mesoscopic particles directly to site treatment is one most promising approaches tissue regeneration. Here, a novel and highly efficient method presented for preparation porous microbeads tailorable dimensions (in range ≈300–1500 mm) with uniform fully interconnected internal texture. The starts generation monodisperse oil‐in‐water emulsion inside flow‐focusing microfluidic device. This later broken‐up, use electric field, into double...
It is commonly acknowledged that polymer composites in service are often subjected to not only intricate mechanical loads but also harsh environmental conditions. The and thermal properties of five particular explored here. composed laminates glass cloth type "E" sheet infilled with a duroplastic matrix. This thermoset polymer-epoxy resin different molecular weights. were fabricated by IZOERG company, which based Poland. final articles 1.5 mm thick 60 cm long 30 wide, the layers arranged...
ABSTRACT Bone tissue regeneration can be affected by various architectonical features of 3D porous scaffold, for example, pore size and shape, strut size, curvature, or porosity. However, the design additively manufactured structures studied so far was based on uniform geometrical figures unit cell structures, which often do not resemble natural architecture cancellous bone. Therefore, aim this study to investigate effect (aka printed) titanium scaffolds designed microtomographic scans...
ABSTRACT The rate of hydrolytic degradation tissue‐engineered scaffolds made from bioresorbable polyesters is dependent on several factors. Some are related to the properties degrading polymeric material, but others geometry porous structure and operating environment. It well known that a given object, or nonporous, lower when it exposed dynamic conditions, flowing medium, than operates in static conditions. most likely reason more efficient removal acidic products vicinity material medium....
Skeletal constructs of diverse marine sponges remain to be a sustainable source biocompatible porous biopolymer-based 3D scaffolds for tissue engineering and technology, especially structures isolated from cultivated demosponges, which belong the Verongiida order, due renewability their chitinous, fibre-containing architecture focused attention. These chitinous have already shown excellent promising results in biomimetics with respect broad diversity cells. However, mechanical features these...
The effectiveness of multifunctional composites that combine a shape-memory polyurethane (PU) matrix with hydroxyapatite (HA) as bioactive agent and antibiotics molecules results from specific composite structure. In this study, structure-function correlations PU-based consisting 3, 5, 10 (wt%) HA (5 wt%) gentamicin sulfate (GeS) model drug were investigated. performed analysis revealed increasing content up to 5 wt% enhanced hydrogen-bonding interaction within the soft segments PU....
Development of hybrid scaffolds and their formation methods occupies an important place in tissue engineering. In this paper, a novel method 3D scaffold is presented as well explanation the differences properties, which were consequence different crosslinking mechanisms. Scaffolds formed from freeze-dried gelatin electrospun poly(lactide-co-glicolide) (PLGA) fibers ratio 1:1 w/w. order to enhance osteoblast proliferation, coated with hydroxyapatite nanoparticles (HAp) using sonochemical...
One important factor affecting the process of tissue regeneration is scaffold stiffness loss, which should be properly balanced with rate regeneration. The aim research reported here was to develop a computer tool for designing architecture biodegradable scaffolds fabricated by melt-dissolution deposition systems (e.g. Fused Deposition Modeling) provide required at each stage degradation/regeneration. original idea presented in paper that engineering can controlled during degradation means...
In this work, we investigate differences in the mechanical and structural properties of tendon fascicle bundles dissected from different areas bovine tendons. The were investigated by means uniaxial tests with relaxation periods hysteresis, dynamic analysis (DMA), as well magnetic resonance imaging (MRI). Uniaxial revealed greater elastic modulus, stress drop during samples posterior side tendon. However, normalized curves did not show a statistically significant difference between specimens...
Abstract Corneal ulcer, which is brought on by a breach in the epithelial barrier, dangerous infection of avascular corneal stroma. New treatment strategies are needed, suppressing aggressive nature disease and including combination different drugs. In this study, vancomycin (VAN) fluconazole (FLU) dual‐drug loaded dual‐layered polyvinyl alcohol gelatin (PVA/GEL) nanofibrous patches produced electrospinning. Scanning electron microscopy (SEM) images show smooth surfaces obtained for both...
SUMMARY The favourable scaffold for bone tissue engineering should have desired characteristic features, such as adequate mechanical strength and three‐dimensional open porosity, which guarantee a suitable environment regeneration. In fact, the design of complex structures like scaffolds is challenge investigators. One aims to achieve best possible strength–degradation rate ratio. this paper we attempt use numerical modelling evaluate material properties designing fabricated via fused...
The manufacturing of artificial bone grafts can potentially circumvent the issues associated with current grafting treatments for critical-size defects caused by pathological disorders, trauma, or massive tumor ablation. In this study, we report on a patient-specific fabrication process in which replicas defects, particular zygomatic and mandibular bones phalanxes hand finger, were manufactured laser stereolithography used as templates creation PDMS molds. Gas-in-water foams cast molds,...