A5043196971- Marine Sponges and Natural Products
- Marine Biology and Environmental Chemistry
- Calcium Carbonate Crystallization and Inhibition
- Nanocomposite Films for Food Packaging
- Diatoms and Algae Research
- Studies on Chitinases and Chitosanases
- Silk-based biomaterials and applications
- Antimicrobial agents and applications
- Oral microbiology and periodontitis research
- Synthetic Organic Chemistry Methods
- Pharmacological Effects of Natural Compounds
- Historical Medical Research and Treatments
- Chemical Synthesis and Analysis
- Iron oxide chemistry and applications
- Polysaccharides Composition and Applications
- Nanomaterials for catalytic reactions
- Advanced biosensing and bioanalysis techniques
- Quinazolinone synthesis and applications
- Chromatography in Natural Products
- Biocrusts and Microbial Ecology
- Phenothiazines and Benzothiazines Synthesis and Activities
- Endodontics and Root Canal Treatments
- Microencapsulation and Drying Processes
- Analytical Methods in Pharmaceuticals
- Safe Handling of Antineoplastic Drugs
National Pirogov Memorial Medical University, Vinnytsya
2015-2025
TU Bergakademie Freiberg
2022-2025
Bogomolets National Medical University
2016
Sponges are a valuable source of natural compounds and biomaterials for many biotechnological applications. Marine sponges belonging to the order Verongiida known contain both chitin biologically active bromotyrosines. Aplysina archeri (Aplysineidae: Verongiida) is well bromotyrosines with relevant bioactivity against human animal diseases. The aim this study was develop an express method production naturally prefabricated 3D bromotyrosine-containing extracts simultaneously. This new based...
Abstract Modern scaffolding strategies include two key ways: to produce requested 3D constructs from corresponding precursors using technological tools, or simply use naturally already pre-fabricated scaffolds if they originate renewable sources. Marine sponges inhabit oceans since the Precambrian. These ancient multicellular organisms possess a broad variety of evolutionary approved and ready skeletal structures, which seem be well applicable as in diverse fields modern bioinspired...
Naturally occurring three-dimensional (3D) biopolymer-based matrices that can be used in different biomedical applications are sustainable alternatives to various artificial 3D materials. For this purpose, chitin-based structures from marine sponges very promising substitutes. Marine the order Verongiida (class Demospongiae) typical examples of demosponges with well-developed chitinous skeletons. In particular, species belonging family Ianthellidae possess chitinous, flat, fan-like fibrous...
Marine sponges remain representative of a unique source renewable biological materials. The demosponges the family Ianthellidae possess chitin-based skeletons with high biomimetic potential. These three-dimensional (3D) constructs can potentially be used in tissue engineering and regenerative medicine. In this study, we focus our attention, for first time, on marine sponge Ianthella labyrinthus Bergquist & Kelly-Borges, 1995 (Demospongiae: Verongida: Ianthellidae) as novel potential...
Structure-based tissue engineering requires large-scale 3D cell/tissue manufacture technologies, to produce biologically active scaffolds. Special attention is currently paid naturally pre-designed scaffolds found in skeletons of marine sponges, which represent a renewable resource biomaterials. Here, an innovative approach the production mineralized natural origin proposed. For first time, method obtain calcium carbonate deposition ex vivo, using living mollusks hemolymph and...
ABSTRACT Demosponges (phylum Porifera) are among the first multicellular organisms on planet and represent a unique archive of biosilica‐based skeletal structures with species‐specific microstructures called spicules. With more than 80 morphotypes, this class sponges is recognized as source amorphous silica superficial ornamentation patterned by organic phases. In study, we investigated spicules selected representatives family Geodiidae (order Tetractinellida), to identify F‐actin‐containing...
Chitin, as a fundamental polysaccharide in invertebrate skeletons, continues to be actively investigated, especially with respect new sources and the development of effective methods for its extraction. Recent attention has been focused on marine crustaceans sponges; however, potential spiders (order Araneae) an alternative source tubular chitin overlooked. In this work, we our from up 12 cm-large Theraphosidae spiders, popularly known tarantulas or bird-eating spiders. These organisms...
The design of new composite materials using extreme biomimetics is crucial importance for bioinspired science. Further progress in research and application these impossible without understanding the mechanisms formation, as well structural features at molecular nano-level. It presents a challenge to obtain holistic underlying interaction organic inorganic phases under conditions harsh chemical reactions biopolymers. Yet, an can lead development unusual-but functional-hybrid materials. In...
Structural bioinspiration in modern material science and biomimetics represents an actual trend that was originally based on the bioarchitectural diversity of invertebrate skeletons, specifically, honeycomb constructs natural origin, which have been humanities focus since ancient times. We conducted a study principles bioarchitecture regarding unique biosilica-based honeycomb-like skeleton deep-sea glass sponge Aphrocallistes beatrix. Experimental data show, with compelling evidence,...
Abstract Three-dimensional (3D) biopolymer-based scaffolds including chitinous matrices have been widely used for tissue engineering, regenerative medicine and other modern interdisciplinary fields extreme biomimetics. In this study, we introduce a novel, electrochemically assisted method 3D chitin isolation from the cultivated marine demosponge Aplysina aerophoba which consists of three main steps: (1) decellularization, (2) decalcification (3) deproteinization along with desilicification...
Skeletal constructs of diverse marine sponges remain to be a sustainable source biocompatible porous biopolymer-based 3D scaffolds for tissue engineering and technology, especially structures isolated from cultivated demosponges, which belong the Verongiida order, due renewability their chitinous, fibre-containing architecture focused attention. These chitinous have already shown excellent promising results in biomimetics with respect broad diversity cells. However, mechanical features these...
Sponges (phylum Porifera) were among the first metazoans on Earth, and represent a unique global source of highly structured diverse biosilica that has been formed tested over more than 800 million years evolution. Poriferans are recognized as archive siliceous multiscaled skeletal constructs with superficial micro-ornamentation patterned by biopolymers. In present study, spicules frameworks selected representatives sponges in such classes Demospongiae, Homoscleromorpha, Hexactinellida...
Three-dimensional chitinous scaffolds often used in regenerative medicine, tissue engineering, biomimetics and technology are mostly isolated from marine organisms, such as sponges (Porifera). In this work, we report the results of electrochemical isolation ready to use matrices three species verongiid demosponges (Aplysina archeri, Ianthella basta Suberea clavata) a perfect example possible morphological chemical dimorphism case chitin sources. The electrolysis concentrated Na2SO4 aqueous...
Aminopolysaccharide chitin is one of the main structural biopolymers in sponges that responsible for mechanical stability their unique 3D-structured microfibrous and porous skeletons. Chitin representatives exclusively marine Verongiida demosponges exists form biocomposite-based scaffolds chemically bounded with biominerals, lipids, proteins, bromotyrosines. Treatment alkalis remains classical approaches to isolate pure from sponge skeleton. For first time, we carried out extraction...
Chitin, as one of nature's most abundant structural polysaccharides, possesses worldwide, high industrial potential and a functionality that is topically pertinent. Nowadays, the metallization naturally predesigned, 3D chitinous scaffolds originating from marine sponges drawing focused attention. These invertebrates represent unique, renewable source specialized chitin due to their ability grow under farming conditions. In this study, development composite material in form chitin-based...
Marine sponges of the subclass Keratosa originated on our planet about 900 million years ago and represent evolutionarily ancient hierarchically structured biological materials. One them, proteinaceous spongin, is responsible for formation 3D fibrous skeletons remains enigmatic with complex chemistry. The objective this study was to investigate interaction spongin iron ions in a marine environment due biocorrosion, leading occurrence lepidocrocite. For purpose, biomimetic approach...
In this study, a facile approach for simultaneous determination of dopamine (DA) and tryptophan (TRP) using 3D goethite–spongin-modified carbon paste electrode is reported. The prepared exhibited excellent electrochemical catalytic activity towards DA TRP oxidation. sensing the modified was investigated cyclic voltammetry, differential pulse impedance spectroscopy. Through voltammetry analysis, two well-separated oxidation peaks were observed at 28 77 mV, corresponding to working electrode,...
The structural biopolymer spongin in the form of a 3D scaffold resembles shape and size numerous species industrially useful marine keratosan demosponges. Due to large-scale aquaculture these sponges worldwide, it represents unique renewable source biological material, which has already been successfully applied biomedicine bioinspired materials science. In present study, from demosponge Hippospongia communis was used as microporous template for development new composite containing goethite...
The chitinous skeleton of the marine demosponge Ianthella basta exhibits a unique network-like 3D architecture, excellent capillary properties, and chemical inertness, making it highly suitable for interdisciplinary research, especially in biomedical applications. This study investigates potential renewable I. scaffolds drug delivery wound dressing. scaffolds, characterized by microtubular structure, were impregnated with selected commercially available antiseptics, including solutions...