A5063163712- Electrospun Nanofibers in Biomedical Applications
- 3D Printing in Biomedical Research
- Wound Healing and Treatments
- Corneal Surgery and Treatments
- Bone Tissue Engineering Materials
- Tissue Engineering and Regenerative Medicine
- Silk-based biomaterials and applications
- biodegradable polymer synthesis and properties
- Electrohydrodynamics and Fluid Dynamics
- Ocular Surface and Contact Lens
- Advanced Drug Delivery Systems
- Cassava research and cyanide
- Advanced Sensor and Energy Harvesting Materials
- Coconut Research and Applications
- Bee Products Chemical Analysis
- Microfluidic and Capillary Electrophoresis Applications
- Periodontal Regeneration and Treatments
- Pickering emulsions and particle stabilization
- Innovative Microfluidic and Catalytic Techniques Innovation
- Additive Manufacturing and 3D Printing Technologies
- Nerve injury and regeneration
- Polymer Surface Interaction Studies
- Hydrogels: synthesis, properties, applications
- Microencapsulation and Drying Processes
- Laser-Ablation Synthesis of Nanoparticles
Marmara University
2019-2024
In order to provide more effective treatment strategies for the rapid healing of diabetic wounds, novel therapeutic approaches need be developed. The potential peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist pioglitazone hydrochloride (PHR) in two different release kinetic scenarios, burst and sustained release, was investigated compared with vitro vivo tests as wound dressings. PHR-loaded fibrous mats were successfully fabricated using polyvinyl-pyrrolidone polycaprolactone by...
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that increasingly common all over the world with high risk of progressive hyperglycemia and microvascular macrovascular complications. The currently used drugs in treatment T2DM have insufficient glucose control can carry detrimental side effects. Several drug delivery systems been investigated to decrease effects frequency dosage, also increase effect oral antidiabetic drugs. In recent years, use microbubbles biomedical...
In this study, the main aim was to fabricate propolis (Ps)-containing wound dressing patches using 3D printing technology. Different combinations and structures of (Ps)-incorporated sodium alginate (SA) scaffolds were developed. The morphological studies showed that porosity developed optimized when 20% (v/v) Ps added solution. pore sizes decreased by increasing concentration up a certain level due its adhesive properties. mechanical, swelling-degradation (weight loss) behaviors, release...
Parkinson’s disease, the second most common neurodegenerative disease in world, develops due to decreased dopamine levels basal ganglia. Levodopa, a precursor used treatment of can be as drug delivery system. This study presents an approach use 3D-printed levodopa-loaded neural tissue scaffolds produced with polylactic acid (PLA) and chitosan (CS) for disease. Surface morphology pore sizes were examined by scanning electron microscopy (SEM). Average 100–200 µm found ideal engineering...
Abstract In this study, polyvinyl alcohol (PVA), gelatin (GEL) and gentamicin (GEN) were used 13PVA/0.5GEL/GEN nanofibers fabricated with the electrospinning method. These crosslinked chemically glutaraldehyde (GA) at different time intervals (2, 3, 4, 5, 5.5 6 h) to observe crosslinking effect on properties of nanofibers. Morphological analysis reported that as increased, nanofiber diameters also increased from 369.26 nm (non‐crosslinked) 447.72 (6 h/crosslinking), respectively. The thermal...
Polymeric microparticles with controlled morphologies and sizes are being studied by researchers in many applications, such as for drug release, healthcare cosmetics. Herein, spherical porous polymeric of different electrospray technique have been developed a viable alternative. In this work, polylactic acid (PLA) shape morphology were successfully produced via an single step. Molecular interactions between the components effect parameters, varying solvent compositions, flow rates voltage on...
Considering the significant advances in nanostructured systems various biomedical applications and escalating need for levan-based nanoparticles as delivery systems, this study aimed to fabricate levan by electrohydrodynamic atomization (EHDA) technique. The hydrolyzed derivative of polysaccharide from Halomonas smyrnensis halophilic bacteria, (hHL), was used. Nanoparticles were obtained optimizing EHDA parameters then they characterized terms morphology, molecular interactions, drug release...
Type 2 diabetes mellitus (T2DM) is a chronic disease characterized by impaired insulin secretion, sensitivity, and hyperglycemia. Diabetic wounds are one of the significant complications T2DM owing to its difficulty in normal healing, resulting wounds. In present work, PCL/PVA, PCL/PVA/PCL, metformin-loaded, PCL/PVA-Met PCL/PVA-Met/PCL hybrid scaffolds with different designs were fabricated using 3D printing. The porosity morphological analysis 3D-printed performed scanning electron...
In this study, two-layer poly(vinyl alcohol)/gelatin (PVA/GEL) nanofiber patches containing cinnamaldehyde (CA) in the first layer and gentamicin (GEN) second were produced by electrospinning method. The morphology, chemical structures, thermal temperatures of pure (PVA/GEL), CA-loaded (PVA/GEL/CA), GEN-loaded (PVA/GEL/GEN), combined drug-loaded (PVA/GEL/CA/GEN) determined scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, differential calorimetry, respectively....
Abstract Corneal ulcer, which is brought on by a breach in the epithelial barrier, dangerous infection of avascular corneal stroma. New treatment strategies are needed, suppressing aggressive nature disease and including combination different drugs. In this study, vancomycin (VAN) fluconazole (FLU) dual‐drug loaded dual‐layered polyvinyl alcohol gelatin (PVA/GEL) nanofibrous patches produced electrospinning. Scanning electron microscopy (SEM) images show smooth surfaces obtained for both...
Abstract Chronic skin wounds pose a global clinical challenge, necessitating effective treatment strategies. This study explores the potential of 3D printed Poly Lactic Acid (PLA) scaffolds, enhanced with Whey Protein Concentrate (WPC) at varying concentrations (25, 35, and 50% wt), for wound healing applications. PLA’s biocompatibility, biodegradability, thermal stability make it an ideal material medical The addition WPC aims to mimic skin’s extracellular matrix enhance bioactivity PLA...