Mazhar Özkan

ORCID: 0000-0002-8745-2493
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About
Contact & Profiles
Research Areas
  • Neuroscience and Neuropharmacology Research
  • Connexins and lens biology
  • Neurological disorders and treatments
  • Neural dynamics and brain function
  • Head and Neck Surgical Oncology
  • Ion channel regulation and function
  • Anatomy and Medical Technology
  • Advanced Neuroimaging Techniques and Applications
  • Artificial Intelligence in Healthcare and Education
  • Craniofacial Disorders and Treatments
  • Fetal and Pediatric Neurological Disorders
  • Memory and Neural Mechanisms
  • Medical and Biological Sciences
  • Gallbladder and Bile Duct Disorders
  • Balance, Gait, and Falls Prevention
  • Sleep and related disorders
  • Cerebral Palsy and Movement Disorders
  • Colorectal Cancer Screening and Detection
  • Parkinson's Disease Mechanisms and Treatments
  • Nerve injury and regeneration
  • Cardiovascular Disease and Adiposity
  • Facial Nerve Paralysis Treatment and Research
  • Epilepsy research and treatment
  • Multiple Sclerosis Research Studies
  • Biochemical effects in animals

Namık Kemal University
2021-2024

Marmara University
2015-2023

Aston University
2017

a b s t r c tIn vivo, theta (4e7 Hz) and gamma (30e80 neuronal network oscillations are known to coexist display phase-amplitude coupling (PAC).However, in vitro, these have for many years been studied isolation.Using an improved brain slice preparation technique we have, using co-application of carbachol (10 mM) kainic acid (150 nM), elicited simultaneous (6.6 ± 0.1 (36.6 0.4 rodent primary motor cortex (M1).Each oscillation showed greatest power layer V. Using variety time series analyses...

10.1016/j.neuropharm.2017.04.009 article EN cc-by Neuropharmacology 2017-04-08

Objective: This study aims to compare hippocampal changes with a correlation of audiological testing results in patients suffering from tinnitus. Methods: Patients diagnosed tinnitus the university hospital between February 2021 and March 2022 were prospectively included by performing magnetic resonance imaging. The volume was determined manually tracing hippocampus' margins on images using Vitrea2® workstation (Canon Medical Systems Vital Images, Minnesota, USA). Statistics used assess...

10.58600/eurjther1925 article EN European Journal of Therapeutics 2024-02-25

Abstract The aim of the study was to determine role isometric strength and range motion in predicting Functional Movement Screen (FMS) scores adults. A total 120 participants (age = 34.62 ± 11.82 years; height 170.56 9.63 cm; weight 73.62 15.39 kg) volunteered participate study. Anthropometric measurements were performed, including height, body weight, muscle mass, fat. Following this, ranges shoulder, hip, knee, ankle joints measured sequentially. Isometric FMS tests then performed. Hip...

10.1186/s13102-024-00935-0 article EN cc-by BMC Sports Science Medicine and Rehabilitation 2024-07-02

The loss of dopamine (DA) in Parkinson's is accompanied by the emergence exaggerated theta and beta frequency neuronal oscillatory activity primary motor cortex (M1) basal ganglia. DA replacement therapy or deep brain stimulation reduces power these oscillations this coincident with an improvement performance implying a causal relationship. Here we provide vitro evidence for differential modulation gamma M1 acting at receptors exhibiting conventional non-conventional pharmacology. Recording...

10.1371/journal.pone.0181633 article EN cc-by PLoS ONE 2017-07-21

<b><i>Background:</i></b> Binge eating (BE) involves the consumption of a large amount food in short period time and loss control during binge episode. It is key feature major subtypes disorders like bulimia nervosa, BE disorder, anorexia nervosa binge/purge type. Alterations mesocorticolimbic pathway play crucial role its pathophysiology. <b><i>Objectives:</i></b> We hypothesized that rats receiving deep brain stimulation (DBS) prelimbic...

10.1159/000486965 article EN Stereotactic and Functional Neurosurgery 2018-01-01

Multiple sclerosis (MS) is a prevalent neurological disease with global impact on patients' lives. Our study aimed to conduct bibliometric analysis of research published in the field pharmacology over past decade. We retrieved original articles MS from journals last ten years through Scopus database. The collected data underwent using VOSViewer software, examining relationships between studies based parameters such as citation, authorship, and organizations. In our country-based analysis,...

10.21597/jist.1402305 article EN Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi 2024-05-22

Background:Morphological properties such as length and tortuosity of the large intestine segments play important roles, especially in interventional procedures like colonoscopy. Objective:Using computed tomography (CT) colonoscopy images, this study aimed to examine morphological features colon's anatomical sections investigate relationship these with each other or age groups. The shapes transverse colon were analyzed using artificial intelligence. Materials Methods:The was conducted a two-...

10.25100/cm.v55i2.5944 article EN Colombia medica 2024-10-29

Aim: This study aimed to investigate if maximal aerobic capacity and pulmonary function tests can be a predictor of cognitive including selective attention inhibitory response in healthy middle-aged adults. Material Methods: The involved 43 people, comprising 31 females 12 males. research included evaluations (VO2max), tests, assessments. VO2max was assessed by the 1-mile Endurance Run/ Walk Test, were conducted via spirometer. Selective measured d2 test, whilst evaluated using...

10.29058/mjwbs.1378769 article EN Medical Journal of Western Black Sea 2024-12-30

Objective: It was aimed to identify the contaminant and determine alternative disinfectant detection in microbial growth
 observed various parts of cadaver stored formalin tank dissection laboratory Marmara University Anatomy
 Department. We also performed a literature review this unusual pathogen.
 Materials Methods: Swab samples were inoculated on agar mediums. After incubation, matrix-assisted laser desorption ionizationtime
 flight mass spectrometry (MALDI-TOF MS)...

10.5472/marumj.1244383 article EN Marmara medical journal 2023-01-30

The thalamo-cortical circuit is important in the genesis of absence epilepsy. This can be influenced by connecting pathways from various parts central nervous system. aim present study to define dento-thalamic connections Wistar animals and compare results with genetic epilepsy rats Strasbourg (GAERS) using biotinylated dextran amine (BDA) tracer. We injected BDA into dentate nucleus 13 (n = 6 n 7 GAERS) animals. were denser connected a wider range thalamic nuclei compared GAERS. was...

10.1089/brain.2019.0694 article EN Brain Connectivity 2019-10-08

Intercellular communication via gap junctions (GJs) has a wide variety of complex and essential functions in the CNS. In present developmental study, we aimed to quantify number astrocytic GJs protein connexin 30 (Cx30) genetic model absence epilepsy rats from Strasbourg (GAERS) at postnatal P10, P30, P60 days epileptic focal areas involved cortico-thalamic circuit. We compared results with Wistar using immunohistochemistry western blotting. The Cx30 immunopositive astrocytes per unit area...

10.1002/syn.22225 article EN Synapse 2022-02-09

Objective: In this study, it is aimed to examine the characteristics and publication rates of oral presentations presented in national congresses.Methods: The data about anatomy congresses (from 2016 2021), including number contributing institutions, institutions that contributed most each year, journals scanned different indexes. titles keywords were using Google Scholar Web Science, journal index details noted.Results: Of we examined our (193) congress 2019 least (47) 2017. rate was...

10.58600/eurjther-343 article EN European Journal of Therapeutics 2023-03-30
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