A5073854558- Colorectal Cancer Surgical Treatments
- Hospital Admissions and Outcomes
- Enhanced Recovery After Surgery
- Colorectal Cancer Screening and Detection
- Anorectal Disease Treatments and Outcomes
- Gut microbiota and health
- Surgical Simulation and Training
- Stoma care and complications
- Cardiac, Anesthesia and Surgical Outcomes
- Surgical site infection prevention
- Innovations in Medical Education
- Esophageal Cancer Research and Treatment
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Patient-Provider Communication in Healthcare
- Intraocular Surgery and Lenses
- Gastrointestinal motility and disorders
- Ophthalmology and Eye Disorders
- Pregnancy and preeclampsia studies
- Diverticular Disease and Complications
- Agriculture and Farm Safety
- Interpreting and Communication in Healthcare
- Lung Cancer Diagnosis and Treatment
- Urinary Tract Infections Management
- Male Reproductive Health Studies
University of Iowa
2021-2024
University of Iowa Hospitals and Clinics
2023-2024
University of Chicago
2016-2021
Cleveland Clinic
2021
NorthShore University HealthSystem
2017
Vanderbilt University
2017
Berman Center for Outcomes and Clinical Research
2016
Johns Hopkins University
2013
Oregon Health & Science University
2013
Yeovil District Hospital
2009
Patients share their microbiota with rooms and nursing staff, this shapes the microbial ecology of hospital environment.
To determine whether intestinal colonization with methicillin-resistant Staphylococcus aureus (MRSA) can be the source of surgical site infections (SSIs).We hypothesized that gut-derived MRSA may cause SSIs via mechanisms in which circulating immune cells scavenge from gut, home to wounds, and infection (Trojan Horse Hypothesis).MRSA gut was achieved by disrupting microbiota antibiotics, imposing a period starvation introducing gavage. Next, mice were subjected injury (30% hepatectomy)...
Horse-related injury can be severe and disabling. We investigated the causes, severity, costs of equestrian with goal prevention. A retrospective review horse-related injuries from 2001 to 2008 identified 231 patients a mean age 38 years Injury Severity Score 11 (range, 1 45). Mean length stay was 5.5 days. Fifty-nine (25%) required 84 surgeries. Helmet use 20 per cent 172 not wearing helmet while mounted, received potentially preventable head injuries. There were three deaths which two...
Bacteria that produce collagen-digesting enzymes (collagenolytic bacteria) have been shown to play a critical and previously unappreciated role in anastomotic leak pathogenesis by breaking down host tissue extracellular matrix proteins. Detection of these bacteria is labor intensive, no screening method currently exists.We evaluated rapid developed detect the presence collagenolytic clinical samples, such as drain fluid, tissue, or feces.We compared new detecting bacterial species with used...
Few studies have investigated trends in global surgical site infection rates colorectal surgery the past decade.
Signal exchange between intestinal epithelial cells, microbes and local immune cells is an important mechanism of homeostasis. Given that macrophages are in close proximity to both the epithelium microbiota, their pathologic interactions may result damage. The present study demonstrates co-incubation murine with E. faecalis strains producing gelatinase (GelE) serine protease (SprE) leads resultant condition media (CM) capable inducing reassembly primary colonic cell monolayers. Following...
We have recently demonstrated that collagenolytic Enterococcus faecalis plays a key and causative role in the pathogenesis of anastomotic leak, an uncommon but potentially lethal complication characterized by disruption intestinal wound following segmental removal colon (resection) its reconnection (anastomosis). Here we hypothesized comparative genetic analysis E. isolates present at site before after surgery would shed insight into mechanisms which strains are selected for predominate...
† Correspondence: S. I. M. F. Ismail, Department of Obstetrics and Gynaecology, Yeovil District hospital, BA21 4AT, UK sharif212121@yahoo.co.uk