A5046324612- Infective Endocarditis Diagnosis and Management
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Reproductive tract infections research
- Antimicrobial Resistance in Staphylococcus
- Syphilis Diagnosis and Treatment
- HIV/AIDS Research and Interventions
- Antibiotics Pharmacokinetics and Efficacy
- Viral-associated cancers and disorders
- Long-Term Effects of COVID-19
- Healthcare cost, quality, practices
- Viral gastroenteritis research and epidemiology
- Autopsy Techniques and Outcomes
- Antibiotic Use and Resistance
- Clostridium difficile and Clostridium perfringens research
- Antifungal resistance and susceptibility
- Celiac Disease Research and Management
- COVID-19 epidemiological studies
- Fungal Infections and Studies
- Colorectal and Anal Carcinomas
- Bacterial Identification and Susceptibility Testing
- Blood disorders and treatments
- Streptococcal Infections and Treatments
- Vaccine Coverage and Hesitancy
- Pharmaceutical studies and practices
The Ohio State University
2021-2025
The Ohio State University Wexner Medical Center
2019-2022
Summa Health System
2011
Abstract Background Rates of anal cancer (AC) in people living with HIV (PLWH) are higher than the general population. Screening for AC can be performed using cytology +/- high-risk human papillomavirus (hrHPV) testing. Until recently, there were no evidence-based consensus guidelines available regarding who should screened or management abnormal results. The International Anal Neoplasia Society (IANS) recommend screening PLWH starting at age 35 men and transgender women have sex (MSM) 45...
Abstract Background Non-AIDS-defining cancers (NADCs) are a leading cause of morbidity and mortality among PWH. With healthcare digitization evolving HIV care models, equitable access to preventative is crucial. We investigated individual system-level factors associated with completion BC CRC screenings. Methods This was single-center, retrospective cohort study from 7/1/2022 7/1/2023. Established PWH (≥ 3 appointments between 7/1/2020-7/1/2023 ≥ 1 within the period) aged 40-75 were...
Abstract Background The duration of antibiotic therapy post cardiac intervention (PCI) for treatment infective endocarditis (IE) remains controversial despite current clinical guidelines. There is paucity data on the PCI relating to pathogens, presence an infected cardiovascular implantable electronic device (CIED), vegetation size, and bacteremia. Due these limitations, may be extended although impact in practice unknown. Methods This was a retrospective study comparing outcomes patients...
Lower mortality has been observed with combination therapy compared to monotherapy for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia; however, there is a lack of evidence continued over de-escalation following bacteremia clearance.This was single-center, retrospective study evaluating patients MRSA hospitalized from November 1, 2011, through July 31, 2019. Patients who received three ten days followed by were directly retained on therapy. The primary composite outcome...
Sexually transmitted infections (STIs) are a common reason for evaluation in the emergency department (ED). Given overlapping risk factors STIs, patients screened gonorrhea and chlamydia should be tested syphilis HIV. Syphilis HIV testing rates ED have been reported to low. The study objective was examine whether collaboration between medicine (EM) infectious disease (ID) providers improved ED.A multidisciplinary team of EM ID formed identify address barriers ED. Syphilis, HIV, chlamydia,...
Daptomycin is associated with a number of adverse effects including eosinophilic pneumonia, hypersensitivity reaction, myopathy, rhabdomyolysis, headache and transaminitis. The high-dose daptomycin have not been fully evaluated in patients end-stage renal disease (ESRD).To determine the incidence characteristics significant receiving severe dysfunction.A single-centre, retrospective study was conducted to assess safety outcomes an estimated creatinine clearance less than 30 mL/min. Adult...
Abstract The Infectious Diseases Society of America Training Program Directors Committee met in October 2022 and discussed an observed increase clinical volume acuity on infectious diseases (ID) services, its impact fellow education. members sought to develop specific goals strategies related improving training program culture, preserving quality education inpatient consult services the clinic, negotiating change at annual IDWeek Director meeting. This paper outlines a presentation ideas...
Abstract The field of infectious diseases (ID) offers a rewarding career path and is widely viewed as an essential subspecialty in medicine. However, recent years, these positive aspects have been overshadowed by concerns surrounding low fellowship match rates, undercompensation, burnout. Infectious Diseases Society America Fellowship Training Program Directors Committee met 2023, discussed the future ID specialty, sought to develop strategies highlight value opportunities for generations,...
Abstract Background Long-acting cabotegravir and rilpivirine (CAB/RPV) offers a promising alternative to daily oral antiretroviral therapy (ART); however, system-level individual challenges in wide scale implementation are anticipated. We describe community, infusion center-based model (ICBM) for administration of CAB/RPV associated clinical outcomes. Methods This was single-center, retrospective cohort study adults with HIV who were referred enrollment the ICBM (Figure 1) from 3/1/22...
The objective of this study was to compare the rate pneumonia resolution in obese (body mass index [BMI], ≥30 kg/m
A specific, clinical-epidemiology, month-long rotation for all infectious disease fellows as well a 1-year subspecialty track provides education in clinical epidemiology during fellowship training. We describe the educational process created at our institution to provide this
Abstract Background Injection drug use is a nationwide epidemic associated with an increased risk of invasive Staphylococcus aureus (S. aureus) infections. Medication-assisted treatment (MAT) effective in reducing substance and increasing adherence to inpatient medical therapy persons injection (PWID). Studies assessing the impact MAT has on completion outpatient parenteral antibiotic (OPAT) are limited. Methods This was single-center, retrospective, cohort study at The Ohio State University...
Purpose: Case Report: A 59 Y/O woman presented to the GI clinic with nausea, vomiting, and weight loss over a month's time. Her past medical history included sarcoidosis, Hashimoto's thyroiditis, lupus. Evaluation revealed an elevated tissue transglutaminase antibody (TTG) IgA, 34 units (0-19) small bowel biopsies which demonstrated intraepithelial lymphocytosis, especially near villous tips, preservation of architecture. She was diagnosed celiac disease started on gluten free diet. Over...
Abstract Background Drug use associated Infective Endocarditis (DU-IE) has been noted to be increasing over the last decade(Clinical Infectious Diseases® 2020;71(7):1664–7). In this study we sought assess unique aspects of DU-IE compared IE not with drug use. We undertook an in-depth descriptive patients who presented course 5 years at one large academic medical center. Table 1 Methods This was a retrospective chart review admitted Ohio State Wexner Medical center between 2013 and 2017....
Abstract Background Guidelines for the management of pulmonary nontuberculous mycobacterial (NTM) infections are well defined; however, similar guidelines treatment disseminated or extrapulmonary NTM lacking. This study aimed to describe our institutional experience in and infections, better characterize disease course, management, outcomes this patient population. Methods single-center retrospective was conducted at The Ohio State University Wexner Medical Center patients who were diagnosed...
Abstract Background Opioid dependence and overdose are at epidemic levels in the United States. Ohio has third highest rate of opioid-related deaths. Infectious complications intravenous drug use (IDU) include increased acquisition hepatitis C, HIV infective endocarditis. In this study, we aimed to characterize cases endocarditis admitted our healthcare system over a five-year period. We additionally sought determine validity using ICD codes identify IDU. Methods Patients with ICD-9 or 10...
Abstract Background Sexually transmitted infections (STIs) disproportionally affect individuals living in underserved areas and Emergency Departments (ED) can play a major role STI screening. Given the overlapping risk factors for STIs, patients screened gonorrhea chlamydia should also be syphilis HIV. Rates of syphilis/HIV screening ED are very low barriers include lack knowledge about risk/prevalence, difficulty with results interpretation, concerns follow-up. Methods The main study...
Abstract Background Histoplasma is a common endemic mycosis in multiple Midwestern states. Most of the data defining epidemiologic risk are from 20th century outbreak investigations. A known exacerbating factor immune suppression; but use biologics, immunosuppressants (ISP), and chemotherapy has advanced since these investigations were conducted. This study sought to clinical tertiary care facility address gaps define evolving epidemiology histoplasmosis Ohio. Methods In single-center...
Abstract Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to increased hospitalizations and utilization of critical care services. There are few studies describing co-morbidities demographics associated with patients re-admitted within 30-days discharge. The purpose this study is describe patient population. Methods This was a single-center, retrospective at Ohio State University Wexner Medical Center identify who were admitted secondary SARS-CoV-2 required...
Abstract Background Monoclonal antibody therapy (MAT) was granted Emergency Use Authorization (EUA) by the U.S. Food and Drug Administration for treatment of mild to moderate coronavirus disease 2019 (COVID-19) in adults with positive SARS-CoV-2 viral testing at high risk progression severe COVID-19 up 10 days symptoms. This study assessed impact MAT on COVID-19-related ER visits, admissions, mortality patients diagnosed COVID-19. Methods a single-center, retrospective The Ohio State...
Abstract Background Sexually transmitted infections (STI), including gonorrhea (GC) and chlamydia (CT), are on the rise in U.S. emergency department (ED) visits for STI-related complaints common. The ED plays a key role testing GC/CT. In addition to genital sites GC/CT, Centers Disease Control Prevention (CDC) recommends extragenital (oral/rectal) based sexual history exposure. this study, we reviewed proportion of GC/CT tests performed at community-based academic Columbus, Ohio. Methods...
Abstract Background Limited options currently exist for treatment of patients diagnosed with symptomatic coronavirus 2019 (COVID-19). Monoclonal antibody therapy (MAT) has been investigated as a therapeutic option COVID-19 in the outpatient setting at high-risk progression to severe disease based on emergency use authorization (EUA) criteria. No published studies have compared outcomes treated different MAT COVID-19. Methods This was single-center, retrospective cohort study The Ohio State...