A5077906636- HIV/AIDS Research and Interventions
- Syphilis Diagnosis and Treatment
- Reproductive tract infections research
- HIV, Drug Use, Sexual Risk
- Poxvirus research and outbreaks
- LGBTQ Health, Identity, and Policy
- Herpesvirus Infections and Treatments
- Bacillus and Francisella bacterial research
- Adolescent Sexual and Reproductive Health
- Genital Health and Disease
- HIV Research and Treatment
- COVID-19 Clinical Research Studies
- Sex work and related issues
- Colorectal and Anal Carcinomas
- HIV/AIDS drug development and treatment
- Cervical Cancer and HPV Research
- Reproductive Health and Technologies
- Innovations in Medical Education
- Adolescent and Pediatric Healthcare
- Antibiotic Use and Resistance
- Female Genital Mutilation/Cutting Issues
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Substance Abuse Treatment and Outcomes
- Plant Virus Research Studies
University of Chicago
2019-2025
Howard Brown Health Center
2022-2024
Rosalind Franklin University of Medicine and Science
2024
Chicago Department of Public Health
2023-2024
University of Chicago Medical Center
2021
Armed Forces Medical College
2012
Abstract Over the past 2 decades, cases of sexually transmitted infections (STIs) from syphilis, gonorrhea, and chlamydia have been rising in United States, disproportionately among gay, bisexual, other men who sex with men, as well racial ethnic minorities all genders. In this review, we address updates about evidence on doxycycline postexposure prophylaxis for prevention bacterial STIs, including efficacy, safety, antimicrobial resistance, acceptability, modeling population impact,...
This Clinical Guideline Synopsis discusses updated guidelines from the Centers for Disease Control and Prevention on prevention, diagnosis, management of sexually transmitted infections, specifically gonorrhea, chlamydia, Mycoplasma genitalium, syphilis.
This study uses electronic medical record data to describe monkeypox infections after a single dose of Modified Vaccinia Ankara-Bavarian Nordic vaccine, live, nonreplicating vaccine indicated for prevention smallpox and infection in adults.
Remdesivir (RDV) is US FDA approved for coronavirus disease 2019 (COVID-19) but not recommended in severe renal impairment (SRI, Creatinine clearance <30mL/min or requiring replacement therapy). Few studies have evaluated RDV patients with SRI.Hospitalized who received between 1 May 2020 and 31 October were analyzed a retrospective chart review. We compared incident adverse events (AEs) without SRI, including hepatotoxicity, nephrotoxicity, any reported AE, mortality, length of stay.Of total...
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The risk of COVID-19 among people living with HIV (PLWH) is largely unknown and there have been very few reported cases in the literature. We report a case series five PLWH COVID-19. identified all patients diagnosis who tested positive for SARS-CoV-2 at University Chicago Medicine between March 1, 2020, April 7, 2020. retrospectively collected data regarding demographics, comorbidities, medications, laboratory test results, radiology outcomes associated All were African American; 80% (4/5)...
The impact of the COVID-19 pandemic on syphilis rates is unknown. A retrospective chart review was performed all patients screened for through universal screening in a large, urban emergency department from June 2019 to 2020. During early (April 2020), remained similar, but rate presumed active infection increased 1.2% 1.8% (prevalence ratio, 1.54; 95% confidence interval, 1.17-2.00; P < 0.01), with significant increases among adolescents and women. Only 19.2% presented STI-related...
Background: Definitions of virological failure (VF) and treatment discontinuation (TD) for long-acting injectable cabotegravir rilpivirine (LAI CAB+RPV) antiretroviral therapy are inconsistent in clinical practice observational studies, complicating interpretation implementation findings. The CONSENSUS-LAI study aimed to establish consistent definitions VF TD enhance evidence transferability support optimal outcomes. Methods: had two phases. Phase I was an international online survey LAI...
Abstract Background Education in infectious disease (ID) is a critical part of an internal medicine curriculum. As the consult service typically high volume and busy, residents other trainees were often not receiving adequate training less common conditions or didactic that may be relevant for their future practice board exams. Our Quality Improvement project sought to improve medical students through integration high-yield lecture services given on Adult ID service.Figure 1:Pre/Post Test...
Abstract Background Over the last decade, infectious disease (ID) fellowship match rates have declined despite increasing workforce need. Many factors may influence rates, including effects of local political climate. Since 2022, many states restricted reproductive and/or LGBT+ rights. As 43% ID physicians identified as women in 2021 (AMA) and 6% graduating medical students entering medicine residencies lesbian, gay, or bisexual from 2016-2019 (Mori, 2021), there is a need to examine impact...
Abstract Background We evaluated eligibility for long-acting injectable (LAI) cabotegravir (CAB) and rilpivirine (RPV) treatment among PWH in a Ryan White-funded HIV clinic assessed factors associated with initiation to identify potential disparities uptake. Methods conducted retrospective cohort analysis who attended the University of Chicago from January 1, 2021 May 31, 2023. were considered eligible LAI-CAB/RPV if they had HIV-1 RNA &lt; 50 copies/mL ≥3 months, no active hepatitis B...
Abstract We describe referrals and uptake of long-acting injectable cabotegravir/rilpivirine at an academic clinic in Chicago. In a pharmacy-led model, 118 (18%) people with HIV were referred 78 (12%) initiated from 1 January 2021 to 31 May 2023. Implementation, especially for who not virally suppressed, requires further support patients, providers, systems.
Background Data on persistent use of HIV pre-exposure prophylaxis (PrEP) is limited among Chinese men who have sex with (MSM). This study aimed to explore factors associated the re-initiation PrEP MSM from a longitudinal demonstration trial. Methods A multi-center cohort was conducted in Guangzhou and Wuhan, China (September 2021–2024), providing 1134 participants 12-month dosage tenofovir disoproxil fumarate emtricitabine (TDF/FTC) as oral PrEP. Following trial, subgroup were invited...
Background. Since May 2022, a large global outbreak of human mpox has predominantly affected men who have sex with men. The strain responsible, Clade IIb, mutated significantly from precursors originating the 2017-18 in Nigeria. Immunity to smallpox, another orthopoxvirus, via previous infection or vaccination provides life-long immunity. However, since 2022 outbreak, recent clusters case been described persons presumed immunity through vaccination. We describe epidemiological and clinical...
With syphilis rates rising rapidly in the United States, novel means of reaching high-risk populations for screening and treatment are needed. Building on successful models emergency department (ED) HIV screening, a routine opt-out program was implemented large, urban, tertiary care hospital ED May 2019. This study aims to assess prevalence this population evaluate routine, model.A retrospective chart review performed all patients screened from June December Demographic information, status,...
The 2022 multinational mpox outbreak has been characterized by unprecedented spread among men who have sex with outside of sub-Saharan Africa. Close contact during and intimacy well established as a key pathway for human-to-human transmission in the current outbreak. Discussions on whether to assign this illness sexually transmitted infection (STI) ongoing since initiation While sexual certainly appears be primary means spread, classifying an STI is inaccurate based its known dynamics,...