Manuel Delgado‐Blanco
A5085403211- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Trace Elements in Health
- Heavy Metal Exposure and Toxicity
- HIV/AIDS drug development and treatment
- Iron Metabolism and Disorders
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Diet, Metabolism, and Disease
- Diabetes and associated disorders
Complexo Hospitalario Universitario A Coruña
2020-2025
Universidade da Coruña
2020-2023
Instituto de Investigación Biomédica de A Coruña
2020
Servicio Gallego de Salud
2020
A National Registry for Wilson disease (WD) was recently started by the Spanish Association Study of Liver (AEEH). We evaluated genetic data patients and differences between regions hospitals. Multicentric observational study from WD after first year. Patients 30 hospitals, in 13/17 (covering 80% population) were included. Genetic available 260/320 patients. More than 130 mutations ATP7B gene registered, majority less 4 alleles, being most prevalent p.Met645Arg (20% mainland Canary Islands),...
MAFLD is the most common cause of chronic liver disease, affecting 25% global population. Patients with T2DM have an increased risk developing MAFLD. In addition, patients a higher advanced forms steatohepatitis and fibrosis. Identifying those critical in order to refer them specialist appropriate management their disease.To estimate fibrosis prevalence cohort identify possible predictors.subjects during regular health check-up were enrolled. Demographic general characteristics measured,...
<h3>Objectives</h3> Sofosbuvir/velpatasvir±ribavirin (SOF/VEL±RBV) and glecaprevir/pibrentasvir (GLE/PIB) are the drug combinations of choice for treating individuals with genotype 3 hepatitis C virus (G3-HCV) infection. The objective this study was to evaluate effectiveness safety SOF/VEL±RBV compared GLE/PIB G3-HCV infection under routine clinical practice conditions. <h3>Methods</h3> We conducted a prospective observational cohort who initiated treatment SOF/VEL +/-RBV or between April...
The aim of this study is to analyze the effectiveness and safety direct-acting antivirals (DAAs) in psychiatric patients with chronic hepatitis C (CHC). Secondary objectives included adherence drug-drug interaction (DDIs) evaluations. Prospective observational comparative carried out during 3 years. Psychiatric were mental illness classified by a team based on clinical records. Main variables sustained virologic response (SVR) at posttreatment week 12 (SVR12) rate on-treatment serious...