A5048913916- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Organ Transplantation Techniques and Outcomes
- Marine Biology and Ecology Research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Systemic Lupus Erythematosus Research
- Marine and coastal plant biology
- HIV/AIDS drug development and treatment
- Hepatitis Viruses Studies and Epidemiology
- Coastal and Marine Management
- Gastroesophageal reflux and treatments
- Marine and fisheries research
- Fish Ecology and Management Studies
- Gastrointestinal disorders and treatments
- Viral gastroenteritis research and epidemiology
- Drug-Induced Hepatotoxicity and Protection
- Pediatric Hepatobiliary Diseases and Treatments
- Autoimmune and Inflammatory Disorders
- Machine Learning in Healthcare
- Diagnosis and Treatment of Venous Diseases
- Artificial Intelligence in Healthcare
- Sarcoidosis and Beryllium Toxicity Research
- Pancreatic and Hepatic Oncology Research
Hospital de Sant Pau
2014-2024
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2010-2024
Universitat Autònoma de Barcelona
2003-2024
Instituto de Salud Carlos III
2005-2024
Centre d'Estudis Avançats de Blanes
2006-2023
Centro de Investigación Biomédica en Red
2014-2023
Consejo Superior de Investigaciones Científicas
2001-2023
Hospital Clínic de Barcelona
2017
Universitat de Barcelona
2000-2017
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2017
After an episode of acute bleeding from esophageal varices, patients are at high risk for recurrent and death. We compared two treatments to prevent — endoscopic ligation combined medical therapy with nadolol isosorbide mononitrate.
Patients who have bleeding from esophageal varices are at high risk for rebleeding and death. We compared the efficacy safety of endoscopic sclerotherapy with nadolol plus isosorbide mononitrate prevention variceal rebleeding.
Paracentesis–induced circulatory dysfunction (PICD) is a recently described complication that can be prevented with the administration of plasma expanders. The aim this study was to compare efficacy saline versus albumin in prevention PICD. Patients were randomized receive or after total paracentesis. readmitted as consequence second episode tense ascites treated paracentesis and alternative expander. After randomization, 35 patients received 37 albumin. Twenty–one for Significant increases...
Minimal hepatic encephalopathy (MHE) reduces quality of life and impacts daily functioning. It is known to impair fitness drive, but deficits in attention reaction may also be associated with falls. Falls have important consequences patients cirrhosis due coagulopathy, osteoporosis, operative risk. However, the relationship between MHE falls has not yet been evaluated. The objective this study retrospectively investigate whether cirrhosis.We included 130 cirrhotic outpatients 43 controls....
We tested the hypothesis that presence of bacterial DNA (bactDNA) in ascitic fluid and serum is associated with decreased survival patients cirrhosis. In a prospective, multicenter study, we analyzed clinical evolution 156 cirrhosis ascites (first or recurrence) lower than 250 polymorphonuclear cells (PMN)/muL, negative bacteriological culture, absence other infections being admitted for evaluation large-volume paracentesis, according to bactDNA at admission. Survival, causes death,...
OBJECTIVES: In compensated cirrhosis, a threshold value of hepatic venous pressure gradient (HVPG) ≥10 mm Hg is required for the development decompensation. However, whether treatment portal hypertension (PHT) can prevent transition into ascites once this level has been reached unclear. Our aim was to assess relationship between changes in HVPG induced by β-blockers and cirrhosis with severe PHT. METHODS: Eighty-three patients without any previous decompensation large esophageal varices ≥12...
Falls are frequent among patients with debilitating disorders and can have a serious effect on health status. Mild cognitive disturbances associated cirrhosis may increase the risk for falls. Identifying subjects at allow implementation of preventive measures. Our aim was to assess predictive value Psychometric Hepatic Encephalopathy Score (PHES) in identifying likely sustain One hundred twenty-two outpatients were assessed using PHES followed specified intervals. third them exhibited...
Monitoring the hemodynamic response of portal pressure (PP) to drug therapy accurately stratifies risk variceal rebleeding (VRB). We assessed whether guiding with hepatic venous gradient (HVPG) monitoring may improve survival by preventing VRB. Patients cirrhosis controlled bleeding were randomized an HVPG‐guided group (N = 84) or a control 86). In both groups, HVPG and acute β‐blocker evaluated at baseline measurements repeated 2‐4 weeks determine chronic response. group, responders treated...
The progression of cirrhosis is associated with alterations in the composition gut microbiome. To assess microbial translocation, we compared serum patients and without ascites characterized ascitic fluid microbiome using 16S rDNA high-throughput sequencing data. A complex specific community was detected but barely detectable healthy controls. presented higher levels lipopolysaccharide binding protein, a marker diversity relative abundance Clostridiales an unknown genus belonging to...
Recent trials have shown that somatostatin (SMT) is as effective sclerotherapy in the treatment of acute variceal bleeding and combination both treatments more than alone. To assess whether addition improves efficacy SMT alone, all patients admitted to our unit with gastrointestinal suspected cirrhosis received a continuous infusion (250 micrograms/h). Endoscopy was performed between 1 5 hours later, esophageal were randomized receive or not sclerotherapy. In groups, continued for days....
Backround and Study Aims: Although high rates of initial hemostasis can be achieved with endoscopic injection therapy in actively bleeding ulcers, the incidence rebleeding is not negligible. Optimal conditions for clotting may require achieving deep sustained acid inhibition to avoid deleterious effect pepsin secretions on hemostatic process. The aim this study was assess whether omeprazole could improve efficacy ranitidine as an adjunct treatment rebleeding.
Abstract Background and Aim Accurate information on the epidemiology of hepatitis C B infection is mandatory to establish a national/regional plan. We aim update prevalence in Catalonia using point‐of‐care tests analyze risk factors related implement linkage‐to‐care circuit. Methods This community‐based study. A random list adult individuals was retrieved from censuses primary care centers. Point‐of‐care for anti‐hepatitis virus (HCV) HBV surface antigen (HBsAg) questionnaire factor...