Shaonan Hu

ORCID: 0000-0003-2039-2489
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About
Contact & Profiles
Research Areas
  • Wound Healing and Treatments
  • Ultrasound and Cavitation Phenomena
  • Ultrasound and Hyperthermia Applications
  • Photoacoustic and Ultrasonic Imaging
  • Silicon and Solar Cell Technologies
  • Advancements in Photolithography Techniques
  • Mesenchymal stem cell research
  • Immune cells in cancer
  • Antimicrobial Peptides and Activities
  • Machine Learning in Bioinformatics
  • vaccines and immunoinformatics approaches
  • 3D IC and TSV technologies
  • Dental materials and restorations
  • Oral microbiology and periodontitis research
  • Reproductive System and Pregnancy
  • Oral Health Pathology and Treatment
  • Protease and Inhibitor Mechanisms
  • Pregnancy and preeclampsia studies
  • Periodontal Regeneration and Treatments
  • Phytochemicals and Medicinal Plants
  • Birth, Development, and Health
  • Gestational Diabetes Research and Management
  • Reproductive tract infections research
  • Thyroid Disorders and Treatments
  • Signaling Pathways in Disease

Leipzig University
2020-2023

Southern Medical University
2022-2023

Changzhi Medical College
2022

The First Hospital of Kunming
2015

Abstract The complex wound environment of diabetic wounds leads to poor treatment efficacy, and the inflammatory disorders vascular injury are primary causes death in such patients. Herein, a sprayable, controllable adaptive, pH‐responsive nanosystem molybdate oligosaccharide (CMO) is specially developed as an immunomodulatory angiogenesis‐promotion material for healing. CMO exhibited release Mo 2+ (COS), specifically response alkalescent observed wounds. provide anti‐inflammatory by...

10.1002/adhm.202302256 article EN Advanced Healthcare Materials 2023-11-03

Recent decades have witnessed remarkable advancements in artificial intelligence (AI), including large language models (LLMs), image and video generative models, embodied AI systems. These led to an explosive increase the demand for computational power, challenging limits of Moore's Law. Optical lithography, a critical technology semiconductor manufacturing, faces significant challenges due its high costs. To address this, various lithography simulators been developed. However, many these...

10.48550/arxiv.2502.06838 preprint EN arXiv (Cornell University) 2025-02-06

Focused ultrasound (FUS) has become an important non-invasive therapy for solid tumor ablation via thermal effects. The cavitation effect induced by FUS is thereby avoided but applied lithotripsy, support drug delivery and the induction of blood vessel destruction cancer therapy. In this study, head neck (FaDu), glioblastoma (T98G), prostate (PC-3) cells were exposed to using in vitro system followed single-dose X-ray radiation (RT) or water bath hyperthermia (HT). Sensitization effects...

10.3390/cells9122595 article EN cc-by Cells 2020-12-03

To identify the genetic linkage mechanisms underlying Parkinson's disease (PD) and periodontitis, explore role of immunology in crosstalk between both these diseases.The gene expression omnibus (GEO) datasets associated with whole blood tissue PD patients gingival periodontitis were obtained. Then, differential analysis was performed to differentially expressed genes (DEGs) deregulated diseases, which defined as genes. Inflammatory response-related (IRRGs) downloaded from MSigDB database...

10.3389/fnagi.2022.1032401 article EN cc-by Frontiers in Aging Neuroscience 2022-12-05

Background. The human antimicrobial peptide defensin beta 1 (DEFB1) has been found to play and anti-inflammatory roles in oral diseases; however, its tumor-regulating role squamous cell carcinoma (OSCC) not yet researched by using an integrative bioinformatics approach. Objective. To investigate the regulating mechanisms of DEFB1 gene OSCC terms expression patterns, prognostic values, biological functions, implication for tumor immunity. Methods. pattern regulatory involvement were...

10.1155/2022/2203615 article EN cc-by Computational and Mathematical Methods in Medicine 2022-02-18

Background . Oxidative stress is implicated in the progression of many neurological diseases, which could be induced by various chemicals, such as hydrogen peroxide (H 2 O ) and acrylamide. Triphala a well‐recognized Ayurvedic medicine that possesses different therapeutic properties (e.g., antihistamine, antioxidant, anticancer, anti‐inflammatory, antibacterial, anticariogenic effects). However, little information available regarding neuroprotective effect on oxidative stress. Materials...

10.1155/2021/6674988 article EN cc-by BioMed Research International 2021-01-01

Focused ultrasound (FUS) has become an important non-invasive therapy for prostate tumor ablation

10.3389/fgene.2023.1122758 article EN cc-by Frontiers in Genetics 2023-04-19

Objective . To identify the key genetic and epigenetic mechanisms involved in wound healing process after injury of oral mucosa. Materials Methods Gene expression profiling datasets pertaining to rapid mucosa were identified using Expression Omnibus (GEO) database. Differential gene analysis was performed differentially expressed genes (DEGs) during mucosal healing. Next, functional enrichment biological processes (BPs) signaling pathways relevant these DEGs. A protein‐protein interaction...

10.1155/2021/6695245 article EN cc-by BioMed Research International 2021-01-01

Periodontal disease has been associated with gestational complications and both conditions have a high prevalence in rural populations from developing regions. A cross-sectional study was carried out to explore the relationship between periodontal inflamed surface area (PISA), blood pressure (BP), and, serum uric acid levels (UA) group of North Chinese pregnant women third trimester pregnancy.Three hundred thirty-five aged 20-34 years, normal body mass index (BMI) were examined during their...

10.3389/fcvm.2022.830732 article EN cc-by Frontiers in Cardiovascular Medicine 2022-03-01

Molybdate-Oligosaccharide Nanosystem The powerful molybdate-oligosaccharide nanosystem (CMO) exhibit pH-responsive release Mo2+ and oligosaccharide to enhance mitochondrial function facilitate the transition of macrophages from M1 M2 phenotype. In article 2302256, Xiuhong Huang, Shaohong co-workers show that within an anti-inflammatory microenvironment, CMO promote angiogenesis through activation PI3K/HIF-1α/VEGF pathway. Such a with immunomodulatory properties angiogenesis-...

10.1002/adhm.202470018 article EN Advanced Healthcare Materials 2024-01-01
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