A5100747278- Cardiac Ischemia and Reperfusion
- Monoclonal and Polyclonal Antibodies Research
- Cardiomyopathy and Myosin Studies
- Natural product bioactivities and synthesis
- Chemokine receptors and signaling
- Advanced Chemical Sensor Technologies
- Magnetic and Electromagnetic Effects
- Pain Mechanisms and Treatments
- Orthopedic Surgery and Rehabilitation
- Pancreatitis Pathology and Treatment
- Cholesterol and Lipid Metabolism
- Health and Wellbeing Research
- Nasal Surgery and Airway Studies
- Reconstructive Facial Surgery Techniques
- Bacteriophages and microbial interactions
- Cerebral Venous Sinus Thrombosis
- Muscle and Compartmental Disorders
- Insect Utilization and Effects
- Trigeminal Neuralgia and Treatments
- Osteoarthritis Treatment and Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Nigella sativa pharmacological applications
- Healthcare and Venom Research
- Natural Compounds in Disease Treatment
- Viral Infections and Immunology Research
China Tobacco
2024
Taian City Central Hospital
2015-2021
Beijing Institute of Technology
2021
Sun Yat-sen University
2020
Jiangxi University of Traditional Chinese Medicine
2020
Shanghai Changzheng Hospital
2010-2014
University of California, San Diego
2013
General Hospital of Guangzhou Military Command
2010
Second Military Medical University
2010
Fudan University
2010
Nemaline myopathy (NM) is a congenital with an estimated incidence of 1∶50.000 live births, caused by mutations in thin filament components, including nebulin, accounting for about 50% the cases. The identification NM cases nonsense resulting loss extreme C-terminal SH3 domain nebulin suggests important role domain, which further supported recent demonstration its IGF-1-induced sarcomeric actin formation through targeting N-WASP to Z-line. To provide insights into functional significance...
Liver X receptors (LXRs) are nuclear that function as ligand-activated transcription factors regulating lipid metabolism and inflammation. Recent discoveries found LXRs could regulate tumor growth in a variety of cancer cell lines. In this study, we investigated the effect LXR activation on melanoma proliferation apoptosis both vitro vivo. Treatment B16F10 A-375 cells with synthetic agonist T0901317 significantly inhibited vitro. Meanwhile, induced dose-dependent manner. Furthermore, western...
Background . Oxidative stress is implicated in the progression of many neurological diseases, which could be induced by various chemicals, such as hydrogen peroxide (H 2 O ) and acrylamide. Triphala a well‐recognized Ayurvedic medicine that possesses different therapeutic properties (e.g., antihistamine, antioxidant, anticancer, anti‐inflammatory, antibacterial, anticariogenic effects). However, little information available regarding neuroprotective effect on oxidative stress. Materials...
Abstract The detection of autoantibodies is critical for diagnosis autoimmune diseases. However, the sensitivity often limited by properties antigens and systems such as enzyme‐linked immunosorbent assay (ELISA). Here, employing multidisplay ability ferritin, a highly sensitive nanocage‐based capture‐detection system designed, which 100–1000‐fold higher than that conventional ELISA methods. capture nanocages are constructed displaying primary Sjögren's syndrome (pSS)‐related antigenic...
Background: On May 12, 2008, an earthquake of magnitude 8.0 on Richter scale struck Sichuan Province China and destroyed Wenchuan County. Two days later, a field hospital from the Second Military Medical University (Shanghai, China) arrived at Anxian County near epicenter as reinforcement before rehabilitation local medical facilities. Surgical services in were supplied by general, orthopedic, plastic, anesthetic, obstetrical surgeons, two physicians. The plastic surgeons responsible for...
Object . Cerebral venous sinus thrombosis (CVST) mainly affects middle‐aged individuals. However, the association between age or prevention strategy with functional outcome remains poorly investigated. Method We identified adult CVST patients in our centers. Functional and were extracted from medical records. Modified Rankin Scale (mRS) ≤ 1 is considered a good outcome. Results A total of 113 identified. The most common presenting symptoms headache (86.72%) nausea/vomiting (56.63%); top two...
Although high density lipoprotein (HDL) improves the functions of endothelial progenitor cells (EPCs), effect HDL ApoAI mimetic peptide reverse-D-4F (Rev-D4F) on EPC mobilization and repair dysfunctions remains to be studied. In this study, we investigated effects Rev-D4F peripheral blood cell subpopulations in C57 mice treated with a fat diet mechanism improving function EPCs impaired by tumor necrosis factor-α (TNF-α). The significantly decreased number EPCs, migratory functions,...
Traditional tobacco feeder is equipped with multiple types of sensors, a large number. Due to the lack effective technical solutions detect sensor status and provide early warnings, feeding process has many drawbacks such as high failure rate serious impact on product quality improvement. This article proposes design an intelligent system based self-diagnosis technology. Firstly, all information collected, analyzed, processed. Then, self-diagnostic algorithms are used detect, judge, alert...
Topical administration of triptolide (TP) is effective in the treatment rheumatoid arthritis (RA), but it can also induce skin irritation. Previous studies have used data mining strategies to analyze application <em>Tripterygium wilfordii</em> RA and shown that TP ferulic acid (FA) be combination due their component compatibility. The aims present study were investigate mechanisms underlying effects identify its on metabolism oxidative damage skin. MTT assay results suggested HaCaT cell...
风蚀是沙区生态建设工程的重要危害形式。分析不同植物种生长对风蚀的响应和适应策略, 确定其耐风蚀阈值, 是优良耐风蚀生态建设植物种筛选的重要理论基础。本文以塔克拉玛干沙漠腹地纵向复合沙垄上栽植的头状沙拐枣人工林为研究对象, 对不同风蚀深度植株的部分枝条节上和全株光合器官生长状况进行了观测和分析。结果表明, 随风蚀强度增加, 头状沙拐枣植株光合器官的单节同化枝数量、单节同化枝总长度和单根同化枝平均长度、单根同化枝平均重量、单株光合器官鲜重、单株同化枝表面积呈降低趋势, 光合器官生长均与风蚀深度呈线性负相关。当风蚀深度小于40 cm时, 头状沙拐枣的单节同化枝数量、单根同化枝长度、单节同化枝总长度降低幅度较小, 但当风蚀深度大于40 cm后, 单节同化枝数量、单根同化枝长度、单节同化枝总长度都大幅降低, 全株光合器官的重量和表面积也大幅下降, 而过强的风蚀可使植株死亡。头状沙拐枣光合器官对风蚀的适应方式是数量和形态变化, 同化枝数量、长度、直径、表面积降低。对风蚀的适应策略是有限资源重点配置, 即植株把能量主要分配在有限的节上, 节上保持一定数量的光合器官生长,...
Objective To explore the antineoplastic effect in vitro of earthworm coelomic fluid (ECF) on growth inhibition and its mechanism for tumor cell lines Siha, SW480, Colo205 PC12.Methods MTT colorimetric assay, flow cytometry morphological ananlysis were used to test antitumor activity normal line Cos7 vitro. Results ECF can inhibit Colo205, PC12 Cos7. But different showed sensitivity. Conclusion EFC significantly proliferation cells by inducing apoptosis. Key words: Oligochaeta; ...
Objective To study the self-rated health on aged chronic kidney disease for outpatients.Methods The evaluation sale(SRHMS V1.0) was used to measure for50 outpatients and 50 common population (retired people). Results significant difference noted in daily physical activities, mobility, total score of subscale,positive emotion,cognitive function, psychosocial subscale, role activity, social resource contact, subscale SRHMS V1.0 between senior nephritis patient population( P ＜0.05) ;but no...