- Electroconvulsive Therapy Studies
- Treatment of Major Depression
- Hemoglobinopathies and Related Disorders
- Diagnosis and Treatment of Venous Diseases
- Infant Development and Preterm Care
- Bipolar Disorder and Treatment
- Breastfeeding Practices and Influences
- Mobile Health and mHealth Applications
- Iron Metabolism and Disorders
- Neonatal Respiratory Health Research
- Child and Adolescent Psychosocial and Emotional Development
- Infant Nutrition and Health
- Diabetes Management and Education
- Food Security and Health in Diverse Populations
- Healthcare Policy and Management
- Health disparities and outcomes
- Renal Transplantation Outcomes and Treatments
- Bone and Joint Diseases
- Healthcare professionals’ stress and burnout
- COVID-19 Impact on Reproduction
- Pressure Ulcer Prevention and Management
- Dementia and Cognitive Impairment Research
- Global Cancer Incidence and Screening
- Medication Adherence and Compliance
- Vaccine Coverage and Hesitancy
Medical University of South Carolina
2016-2025
Yale University
2025
Technology Applications (United States)
2013-2023
RELX Group (Netherlands)
2022
National Center for Advancing Translational Sciences
2017-2022
National Institutes of Health
2017-2022
National Institute of Nursing Research
2017-2022
Florida College
2021
University of Florida
2013-2021
University of South Carolina
2011-2021
Objective To compare the relative efficacy of electroconvulsive therapy (ECT) in psychotic and nonpsychotic patients with unipolar major depression. Methods The outcome an acute ECT course 253 (n = 176) 77) depression was assessed first phase ongoing National Institute Mental Health-supported four-hospital collaborative study continuation treatments after successful courses. administered bilateral electrode placement at 50% above titrated seizure threshold. remission criteria were rigorous:...
<h3>Background</h3> Although electroconvulsive therapy (ECT) has been shown to be extremely effective for the acute treatment of major depression, it never systematically assessed as a strategy relapse prevention. <h3>Objective</h3> To evaluate comparative efficacy continuation ECT (C-ECT) and combination lithium carbonate plus nortriptyline hydrochloride (C-Pharm) in prevention depressive relapse. <h3>Design</h3> Multisite, randomized, parallel design, 6-month trial performed from 1997...
Article Abstract Background: Remission of illness in patients with major depressive disorder (MDD) is achieved less than half initially treated medication. Electroconvulsive therapy (ECT) another treatment option. We report the speed response and remission rates a cohort depressed who received course acute-phase ECT initial phase an ongoing multicenter randomized trial continuation versus pharmacotherapy. Method: Patients MDD according to DSM-IV criteria bilateral 3 times weekly. Prior each...
Background Electroconvulsive therapy (ECT) is an effective treatment for major depression. Optimising efficacy and minimising cognitive impairment are goals of ongoing technical refinements. Aims To compare the effects a novel electrode placement, bifrontal, with two standard placements, bitemporal right unilateral in ECT. Method This multicentre randomised, double-blind, controlled trial (NCT00069407) was carried out from 2001 to 2006. A total 230 individuals depression, bipolar unipolar,...
The Prolonging Remission in Depressed Elderly (PRIDE) study evaluated the efficacy of right unilateral ultrabrief pulse electroconvulsive therapy (ECT) combined with venlafaxine for treatment geriatric depression.PRIDE was a two-phase multisite study. Phase 1 an acute course ECT, open-label at seven academic medical centers. In phase 2 (reported separately), patients who had remitted were randomly assigned to receive pharmacotherapy (venlafaxine plus lithium) or continuation ECT. 1,...
The randomized phase (phase 2) of the Prolonging Remission in Depressed Elderly (PRIDE) study evaluated efficacy and tolerability continuation ECT plus medication compared with alone depressed geriatric patients after a successful course 1).PRIDE was two-phase multisite study. Phase 1 an acute right unilateral ultrabrief pulse ECT, augmented venlafaxine. 2 two treatment arms: only arm (venlafaxine lithium, over 24 weeks) (four treatments month, additional as needed, using Symptom-Titrated,...
OBJECTIVE: This study assessed the incidence, severity, and course of expressed suicidal intent in depressed patients who were treated with ECT. The data are from first phase an ongoing, collaborative multicenter study, overall aim which was to compare continuation ECT pharmacotherapy prevention relapse after a successful METHOD: Suicidal intent, as by during interview, scored at baseline before each session item 3 on 24-item Hamilton Depression Rating Scale 444 unipolar depression. RESULTS:...
Objective . Current generation smartphones' video camera technologies enable photoplethysmographic (PPG) acquisition and heart rate (HR) measurement. The study objective was to develop an Android application compare HRs derived from a Motorola Droid electrocardiograph (ECG) Nonin 9560BT pulse oximeter readings during various movement-free tasks. Materials Methods were collected simultaneously 14 subjects, ages 20 58, healthy or with clinical conditions, using the 3 devices 5-minute periods...
Mobile phone based remote monitoring of medication adherence and physiological parameters has the potential improving long-term graft outcomes in recipients kidney transplants. This technology is promising as it relatively inexpensive, can include intuitive software may offer ability to conduct close patient a non-intrusive manner. includes optimal management comorbidities such hypertension diabetes. There is, however, lack data assessing attitudes renal transplant toward this technology,...
Feeding breastmilk to premature infants decreases morbidity but is often limited owing an insufficient milk supply and delayed attainment of lactogenesis stage II. Early initiation expression following delivery has been shown increase production in mothers very low-birth-weight (VLBW) infants. Although recommendations for this population include within 6 hours delivery, little evidence exists support these guidelines. This study compared volume timing II VLBW who initiated versus those after...
Background: Mobile phone–based interventions present a means of providing high quality health care to hard-to-reach underserved populations. Migrant farm workers (MFWs) are among the most populations in United States due prevalence chronic diseases yet limited access care. However, it is unknown if MFWs have mobile phone devices used (mHealth) interventions, or they willing use such technologies. Objective: Determine rates ownership and willingness mHealth strategies MFWs. Methods: A...
To determine the relative efficacy of electroconvulsive therapy (ECT) in treatment bipolar (BP) and unipolar (UP) depressive illness clarify its role BP depression.Patients referred for ECT with both UP depressions. [classified by Structured Clinical Interview DSM (SCID-I) criteria history mania] were included a multi-site collaborative, double-masked, randomized controlled trial three electrode placements - right unilateral, bifrontal or bitemporal permutated block randomization scheme.Of...
African Americans and Hispanics have disproportionate rates of uncontrolled essential hypertension (EH) compared to Non-Hispanic Whites. Medication non-adherence (MNA) is the leading modifiable behavior improved blood pressure (BP) control. The Smartphone Adherence Stops Hypertension (SMASH) program was developed using a patient-centered, theory-guided, iterative design process. Electronic medication trays provided reminder signals, Short Message Service [SMS] messaging reminded subjects...
The drivers of trauma disparities are multiple and complex; yet, understanding the causes will direct needed interventions. aims this article to (1) explore how injured patient, his or her social environment, health care system interact contribute examine evidence in support interventions (2) develop a conceptual framework that captures socioecological context disparities. Using scoping review methodology, articles were identified through PubMed CINAHL between 2000 2015. Data extracted on...
Background: In 2019, a deadly virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for disease 2019 (COVID-19), emerged. December 2020, two mRNA-based COVID-19 vaccines were approved use in the United States, which provide immunity to those receiving vaccine. Maternally derived antibodies are key element of infants' immunity. Certain given pregnant and lactating mothers infants through transmission across placenta, umbilical cord (IgG), human milk (IgA)....
BACKGROUND: Low levels of serum 25-hydroxyvitamin D (25[OH]D), a reliable measurement vitamin D, have been implicated in several mood disorders. To date, studies exploring the relationship between and postpartum depression are absent from literature. OBJECTIVES: determine whether exists symptoms associated with to if 25(OH) can predict incidence depression. STUDY DESIGN: An exploratory, descriptive study using convenience sample 97 women attending seven monthly visits. Women provided 25(OH)D...
Objective: We sought to examine the relationship of seizure threshold (ST) age and other demographic characteristics in a large sample where ST was determined by dose titration (DT) method. also compared resulting stimulation levels estimates predicted an age-based formula, half-age (HA) Methods: In multicenter prospective study, patients received standardized course bilateral electroconvulsive therapy for major depression using brief pulse device. The at first treatment fixed algorithm...
Context— Very few patient-centered, theory-guided programs for medication adherence and blood pressure control have been conducted in kidney transplant recipients. Objective— To evaluate preliminary indications of sustainability improved recipients 12 months after completion a 3-month randomized controlled trial mobile health pilot program to improve adherence. Participants Design— A total 18 the 19 participants were contacted all consented inclusion retrospective analysis their medical...