Guillermo Santoscoy‐Ascencio

ORCID: 0000-0003-2044-8788
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About
Contact & Profiles
Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Immunotherapy and Immune Responses
  • Cervical Cancer and HPV Research
  • Hepatitis B Virus Studies
  • Macrophage Migration Inhibitory Factor
  • Genital Health and Disease
  • Vaccine Coverage and Hesitancy

Universidad de Guadalajara
2019-2023

Mexican Social Security Institute
2020

Abstract Background Macrophage migration inhibitory factor (MIF) is a cytokine capable of stimulating inflammatory and matrix metalloproteinase production from macrophages synovial fibroblasts, which leads to persistent inflammation bone degradation, two the major pathological processes in rheumatoid arthritis (RA). The aim this study was evaluate association MIF promoter polymorphisms (−794CATT 5‐8 rs5844572 −173G > C, rs755622 ), circulating levels, mRNA expression with RA...

10.1002/mgg3.1037 article EN cc-by Molecular Genetics & Genomic Medicine 2019-11-07

Understanding the humoral immune response dynamics carried out by B cells in COVID-19 vaccination is little explored; therefore, we analyze changes induced different cellular subpopulations of after with BNT162b2 (Pfizer-BioNTech).This prospective cohort study evaluated thirty-nine immunized health workers (22 prior and 17 without COVID-19) ten subjects not vaccinated against SARS-CoV-2 (control group). cell (transitional, mature, naïve, memory, plasmablasts, early plasmablast,...

10.2147/jir.s374304 article EN cc-by-nc Journal of Inflammation Research 2022-08-01

This study aimed to analyze the dynamics, duration, and production of total neutralizing antibodies induced by BNT162b2 vaccine possible effect gender prior SARS-CoV-2 infection on generation these antibodies. Total were quantified via chemiluminescent microparticle immunoassay (CMIA), using cPass kit. Individuals with a history COVID-19 produced twice as many than vaccinated individuals without infection, an exponential increase observed in just six days. In those history, similar antibody...

10.3390/vaccines11061127 article EN cc-by Vaccines 2023-06-20
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