- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Respiratory Support and Mechanisms
- Respiratory and Cough-Related Research
- Delphi Technique in Research
- Nursing Diagnosis and Documentation
- Chronic Disease Management Strategies
- School Health and Nursing Education
- Pediatric health and respiratory diseases
- Travel-related health issues
- Health Promotion and Cardiovascular Prevention
- Inhalation and Respiratory Drug Delivery
- Nursing Roles and Practices
- Pharmaceutical studies and practices
- Emergency and Acute Care Studies
- Vaccine Coverage and Hesitancy
- Scoliosis diagnosis and treatment
- Behavioral Health and Interventions
- Amyotrophic Lateral Sclerosis Research
- Acute Ischemic Stroke Management
- Global Cancer Incidence and Screening
- Health Policy Implementation Science
- Childhood Cancer Survivors' Quality of Life
- Cystic Fibrosis Research Advances
- Healthcare Policy and Management
Norfolk Community Health and Care NHS Trust
2013-2024
Observational & Pragmatic Research Institute
2016-2018
Mount Medical Centre
2017-2018
University of Aberdeen
2005-2016
National University Hospital
2016
University of Southampton
2016
Singapore General Hospital
2016
Johannes Gutenberg University Mainz
2016
NHS England
2016
NHS Digital
2016
The British Thoracic Society (BTS) Home Oxygen Guideline provides detailed evidence-based guidance for the use of home oxygen patients out hospital. Although majority evidence comes from in with chronic obstructive pulmonary disease, scope includes a variety long-term respiratory illnesses and other groups whom is currently ordered, such as those cardiac failure, cancer end-stage cardiorespiratory terminal illness or cluster headache. It explores base different modalities therapy...
Most randomized trials of treatment for asthma study highly selected patients under idealized conditions.We conducted two parallel, multicenter, pragmatic to evaluate the real-world effectiveness a leukotriene-receptor antagonist (LTRA) as compared with either an inhaled glucocorticoid first-line asthma-controller therapy or long-acting beta(2)-agonist (LABA) add-on in already receiving therapy. Eligible primary care 12 80 years age had impaired asthma-related quality life (Mini Asthma...
<i>Background:</i> Symptom-based questionnaires may enhance chronic obstructive pulmonary disease (COPD) screening in primary care. <i>Objectives:</i> We prospectively tested questions to help identify COPD among smokers without prior history of lung disease. <i>Methods:</i> Subjects were recruited via random mailing care practices Aberdeen, UK, and Denver, Colo., USA. Current former aged 40 or older with no respiratory diagnosis medications the past year...
Patterns of health-care use and comorbidities present in patients the period before diagnosis chronic obstructive pulmonary disease (COPD) are unknown. We investigated these factors to inform future case-finding strategies.We did a retrospective analysis clinical cohort UK with data from Jan 1, 1990 Dec 31, 2009 (General Practice Research Database Optimum Patient Care Database). assessed aged 40 years or older who had an electronically coded COPD their primary care records minimum 3...
Purpose: Acute COPD exacerbations account for much of the rising disability and costs associated with COPD, but data on predictive risk factors are limited. The goal current study was to develop a robust, clinically based model predict frequent exacerbation risk. Patients methods: identified from Optimum Patient Care Research Database (OPCRD) diagnostic code forced expiratory volume in 1 second/forced vital capacity ratio <0.7 were included this historical follow-up if they ≥40 years old had...
Many patients with obstructive lung disease (OLD) carry an inaccurate diagnostic label. Symptom-based questionnaires could identify persons likely to need spirometry.We prospectively tested questions derived from a comprehensive literature review and international Delphi panel help chronic OLD (COPD) in prior evidence of OLD.Subjects were recruited via random mailing primary-care practices Aberdeen, Scotland, Denver, Colorado. Persons aged 40 older reporting any diagnosis or respiratory...
Background: Randomized controlled trials indicate that addition of a long-acting muscarinic antagonist (LAMA) such as tiotropium may improve asthma control and reduce exacerbation risk in patients with poorly asthma, but broader clinical studies are needed to investigate the effectiveness LAMA real-life care. Methods: Medical records adults (aged ≥18 years) prescribed were obtained from UK Optimum Patient Care Research Database for period 2001–2013. Patients diagnosed chronic obstructive...
Clinical trials of tiotropium have principally recruited patients from secondary care with more severe chronic obstructive pulmonary disease (COPD), and typically had included limitation concomitant medication. In primary care, which is the most common setting for COPD management, many may milder disease, also take a broad range This randomised, placebo-controlled, parallel-group, 12-week, 44-centre study investigated efficacy (trough forced expiratory volume in 1 second [FEV1] response)...
Price, David; Musgrave, Stanley D.; Shepstone, Lee; Hillyer, Elizabeth V.; Sims, Erika J.; Gilbert, Richard F.T.; Juniper, F.; Ayres, Jon G.; Kemp, Linda; Blyth, Annie; Wilson, Edward C.F.; Wolfe, Stephanie; Freeman, Daryl; Mugford, H. Miranda; Murdoch, Jamie; Harvey, Ian Author Information
Objectives To evaluate, under real-life practice conditions in UK primary care, asthma control and cost-effectiveness of commencing therapy with leukotriene antagonists compared inhaled corticosteroids (ICSs) as initial controller long-acting β2-agonist add-on for patients uncontrolled already receiving ICS. Comparisons were made terms short-term efficacy (2 months) longer-term effectiveness years). Design The study comprised two randomised controlled trials, powered equivalence. Incremental...
Incorrect inhaler technique is a common cause of poor asthma control. This two-phase pragmatic study evaluated mastery and maintenance with DuoResp® (budesonide-formoterol [BF]) Spiromax® compared Symbicort® (BF) Turbuhaler® in patients who were receiving inhaled corticosteroids/long-acting β2-agonists. In the initial cross-sectional phase, randomized to 6-step training protocol empty Spiromax Turbuhaler devices. Patients initially demonstrating ≥1 error their current device, then achieving...
The purpose of the quality standards document is to provide healthcare professionals, commissioners, service providers and patients with a guide care that should be met for home oxygen provision in UK, together measurable markers good practice. Quality statements are based on British Thoracic Society (BTS) Guideline Home Oxygen Use Adults.Development BTS Standards follows process standard production National Institute Health Care Excellence manual development standards.10 have been...