- Biomedical Ethics and Regulation
- Mesenchymal stem cell research
- Microbial Inactivation Methods
- Health Systems, Economic Evaluations, Quality of Life
- Quantum Dots Synthesis And Properties
- Hormonal and reproductive studies
- IgG4-Related and Inflammatory Diseases
- Chemokine receptors and signaling
- Speech and Audio Processing
- Reproductive System and Pregnancy
- Vasculitis and related conditions
- Electrostatic Discharge in Electronics
- Wound Healing and Treatments
- Ethics and Legal Issues in Pediatric Healthcare
- Hearing Loss and Rehabilitation
- Toxin Mechanisms and Immunotoxins
- Analytical Chemistry and Chromatography
- Endometrial and Cervical Cancer Treatments
- Vestibular and auditory disorders
- Hematopoietic Stem Cell Transplantation
- Phonetics and Phonology Research
- Full-Duplex Wireless Communications
- Neonatal Respiratory Health Research
- Transgenic Plants and Applications
- Hearing, Cochlea, Tinnitus, Genetics
State Research Institute Centre for Innovative Medicine
2014-2025
Gastroenterology faces significant challenges due to the global burden of gastrointestinal (GI) diseases, driven by socio-economic disparities and their wide-ranging impact on health healthcare systems. Advances in molecularly imprinted polymers (MIPs) offer promising opportunities for developing non-invasive, cost-effective diagnostic tools that enhance accuracy accessibility GI disease detection. This research explores potential MIP-based sensors revolutionizing diagnostics improving early...
Calcium electroporation (CaEP) is an innovative approach to treating cancer, involving the internalization of supraphysiological amounts calcium through electroporation, which leads cell death. CaEP enables replacement chemotherapeutics (e.g., bleomycin). Here, we present a standard microsecond (μsCaEP) and novel high-frequency nanosecond protocols for (nsCaEP) elimination carcinoma tumors in C57BL/6J mice. We show efficacy eliminating increasing their survival rates vivo. The antitumor...
Head and neck cancer continues to be among the most prevalent types of globally, yet it can managed with appropriate treatment approaches. Presently, chemotherapy radiotherapy stand as primary modalities for various groups regions affected by head cancer. Nonetheless, these treatments are linked adverse side effects in patients. Moreover, due tumor resistance multiple drugs (both intrinsic extrinsic) radiotherapy, along numerous other factors, recurrences or metastases often occur....
Osteoarthritis (OA) ranks as the prevailing type of arthritis on a global scale, for which no effective treatments are currently available. Arterial hypertension is common comorbidity in OA patients, and antihypertensive drugs, such nifedipine (NIF), may affect course progression. The aim this preclinical study was to determine effect healthy cartilage, depending its route administration. In study, we used destabilization medial meniscus develop mouse model OA. Nifedipine applied per os or...
Background and Objectives: Granulomatosis with Polyangiitis (GPA) is a rare, autoimmune, multisystemic disease characterized by vasculitis necrotizing granuloma that commonly affects the upper lower respiratory tract kidneys. Audiovestibular dysfunction in GPA diseases may have different clinical presentations. The aim of present study was to evaluate hearing function patients compare results healthy control group. Materials Methods: A total 34 individuals participated study. group consisted...
Immunoglobulin G4-related disease (IgG4-RD) is a systemic condition which could present as local infiltration of skull base structures. We report case IgG4-RD with the temporal bone and surrounding structures in patient vasculitis on steroids. A 31-year-old woman presented right-sided facial weakness, headache, right ear hearing loss. On examination, redness retraction tympanic membrane paresis (House-Brackman IV) were noted. Computed tomography imaging showed mastoiditis, lobe stroke, brain...
Background and Objectives: Speech audiometry employs standardized materials, typically in the language spoken by target population. Language-specific nuances, including phonological features, influence speech perception recognition. The material of tests for assessment word recognition comprises lists words that are phonemically or phonetically balanced. As auditory is influenced a variety linguistic it necessary to develop test materials listener’s mother tongue. objective our study was...
Advanced therapy medicinal products – new category of biological pharmaceutical products, which covers somatic cell therapy, gene tissue-engineered and combined advanced products. Regulation (EC) No 1394/2007 defined set up special rules for intended to be placed on the market in Member States prepared industrially or manufactured by a method involving an industrial process. The scope is not applicable are prescribed under exclusive professional responsibility medical practitioner,...