- Mechanical Behavior of Composites
- Textile materials and evaluations
- Structural Analysis and Optimization
- Sports Dynamics and Biomechanics
- Malaria Research and Control
- Infrastructure Maintenance and Monitoring
- Mosquito-borne diseases and control
- Asphalt Pavement Performance Evaluation
- Metal Forming Simulation Techniques
- Manufacturing Process and Optimization
- Geotechnical Engineering and Underground Structures
- Optical measurement and interference techniques
- Structural Health Monitoring Techniques
- Sports Performance and Training
- Tree Root and Stability Studies
- Sports Analytics and Performance
- Aerospace Engineering and Energy Systems
- Experimental and Theoretical Physics Studies
- Additive Manufacturing and 3D Printing Technologies
- Structural Analysis of Composite Materials
- Cellular and Composite Structures
- Vibration and Dynamic Analysis
- Viral Infections and Vectors
- Mechanical Engineering and Vibrations Research
- Fluid Dynamics and Vibration Analysis
University of Massachusetts Lowell
2016-2025
University of Massachusetts Boston
2021
William James College
2021
AstraZeneca (Brazil)
2021
New York State Department of Health
2018-2020
University of Central Florida
2020
University of York
2018
Federal Highway Administration
1995-2012
Turner-Fairbank Highway Research Center
1998-2004
United States Army Medical Research Directorate - Africa
1988-1995
Human platelet thrombospondin adsorbed on plastic promotes attachment and spreading of human G361 melanoma cells. Attachment is rapid, maximal by 90 min with 60-90% the attached cells spread. In contrast, but not C32 cells, which attach spread only laminin substrates. The specificity these interactions regions molecule involved in were examined using proteolytic fragments inhibition studies. sulfated fucan, fucoidan, monoclonal antibody A2.5, directed against heparin-binding domain...
We have investigated the expression of a strain-specific malarial antigen on surface erythrocytes infected with knobless (K-) variants knob-positive (K+) strains Plasmodium falciparum. Aotus blood K+ or K- parasites derived from two independent geographical isolates (Malayan camp and Santa Lucia) was iodinated by lactoperoxidase method. Infected uninfected were then separated new procedure involving equilibrium density sedimentation Percoll gradient containing sorbitol. Strain-specific...
Abstract The compressive‐stress strain response of polyurethane foam under uniaxial compressive impact loading has been studied. development a constitutive model from rate controlled compression tests is detailed. Density and temperature functions have added to the integral power proposed by Schwaber, Meincke, Nagy. assumes that effects density, temperature, on stress are separable functions. correlated well with actual static was used successfully predict energy absorbing loading.
The increasing demand for wind power has led to a significant increase in the number and size of turbine blades manufactured globally. As physical turbines deployed grow, probability manufacturing defects being present composite also increases. capital blade costs operational maintenance expenses ever larger systems, need inspection structural health large-scale during operation critically One method locating quantifying defects, while allowing situ measurement blades, is monitoring...
We have compared the surface radio-iodinated proteins of uninfected and Plasmodium falciparum-infected erythrocytes from natural infections human patients. Cryopreserved infected blood Gambian children with falciparum malaria was thawed, cultured to middle trophozoite stage, radio-iodinated. Trophozoite-infected cells were enriched about 10-fold on a Percoll gradient newly designed separate based their differential permeability sorbitol. Infected fraction in parasitized same sample obtained...
The research presented in this article focuses on a 9-m CX-100 wind turbine blade, designed by team led Sandia National Laboratories and manufactured TPI Composites Inc. key difference between the blade baseline blades is that contains fabric wave defects of controlled geometry inserted at specified locations along length. defect was tested Wind Technology Center Renewable Energy Laboratory using schedule cycles increasing load level until failure detected. Researchers used digital image...
The efficacy of an oral 8-aminoquinoline (8-[[6-(diethylamino)hexyl]amino]-6-methoxy-4-methylquinoline) (WR6026) in the treatment 16 patients with kala azar was evaluated. first 8 received therapy for 2 weeks at a dosage 0.75–1.00 mg/(kg · d); 1 patient cured, and regard to other 7, 1-logarithm decrease number splenic parasites clinical improvement were noted. next 4 same daily (1 mg/[kg d]); 4, 1- 2-1og decreases (in weight, liver spleen size, hemoglobin level, leukocyte count) associated...
The profound changes in the morphology, antigenicity, and functional properties of host erythrocyte membrane induced by intraerythrocytic parasites human malaria Plasmodium falciparum are poorly understood at molecular level. We have used mouse mAbs to identify a very large malarial protein (Mr approximately 300,000) that is exported from parasite deposited on cytoplasmic face membrane. This denoted P. 2 (Pf EMP 2). did not react with surface intact infected erythrocytes, nor was Pf...
To identify vaccine relevant T cell epitopes on the circumsporozoite (CS) protein of Plasmodium falciparum, lymphocyte proliferative responses to 10 CS derived peptides were studied in 28 adult Kenyans, and correlated with resistance malaria. Eight peptides, six which not overlapping, induced proliferation lymphocytes from one five volunteers, suggesting either genetic restriction response each epitopes, or dominance some sites immunizing sporozoites. The volunteers radically cured malaria...
Parachute suspension lines shed vortices during descent, and these develop oscillating aerodynamic forces that can induce forced parasitic vibrations of the have an adverse impact on parachute system. Understanding line’s mechanical behavior assist in comprehending are experienced by lines. A well calibrated structural model line could be used to help identify how braid’s architecture contributes its explore if a designed mitigate vibrations. In current study, mesomechanical finite element...
Solvents have long been recognized as one of the principal sources waste from chemical industry, particularly fine manufacturing.1,2 While neoteric solvents with minimal atmospheric impact such supercritical fluids and ionic liquids show promise for some applications, most processes remain dependent on organic solvents. As a result, last two decades seen rapid increase in development deployment bio-derived biodegradable “green” solvents.3 Design pay close attention to...
Parachute suspension lines shed vortices during descent, and these develop oscillating aerodynamic forces that can induce forced parasitic vibrations of the lines, which have an adverse impact on parachute system. Understanding line’s mechanical behavior assist in studying experienced by lines. A well-calibrated structural model line could be used to help identify how braid’s architecture contributes its explore if a designed mitigate vibrations. In current study, mesomechanical finite...