- Bee Products Chemical Analysis
- Insect and Pesticide Research
- Gut microbiota and health
- Nanoparticle-Based Drug Delivery
- Heme Oxygenase-1 and Carbon Monoxide
- Glioma Diagnosis and Treatment
- MicroRNA in disease regulation
- Plant tissue culture and regeneration
- Cell death mechanisms and regulation
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Genomics, phytochemicals, and oxidative stress
- Genetic and phenotypic traits in livestock
- Multiple Myeloma Research and Treatments
- Plant Molecular Biology Research
- Advanced Drug Delivery Systems
- Exercise and Physiological Responses
- Nanoplatforms for cancer theranostics
- Alcohol Consumption and Health Effects
- Radiomics and Machine Learning in Medical Imaging
- Multimodal Machine Learning Applications
- Sulfur Compounds in Biology
- Plant Genetic and Mutation Studies
- Climate Change Policy and Economics
- Traditional Chinese Medicine Analysis
Beijing University of Chinese Medicine
2021-2025
Huazhong University of Science and Technology
2019-2025
Philadelphia College of Osteopathic Medicine
2014-2024
Wuhan University of Technology
2018-2024
The University of Adelaide
2020-2024
Shandong Agricultural University
2014-2024
Wuhan University
2024
Ji Hua Laboratory
2024
China Institute of Atomic Energy
2024
Xi'an Technological University
2024
Visual Question Answering (VQA) methods have made incredible progress, but suffer from a failure to generalize. This is visible in the fact that they are vulnerable learning coincidental correlations data rather than deeper relations between image content and ideas expressed language. We present dataset takes step towards addressing this problem it contains questions two languages, an evaluation process co-opts well understood image-based metric reflect method’s ability reason. Measuring...
Sustained release of therapeutic agents into tumor cells is a potential approach to improve efficacy, decrease side effects, and the drug administration frequency. Herein, we used modified double-emulsion solvent evaporation (DSE) method prepare novel morphological paclitaxel (PTX) loaded poly(lactide-co-glycolide) (PLGA) microspheres (MS). The prepared rough PTX-PLGA-MS possessed microporous surface highly porous internal structures, which significantly influenced entrapment behaviors. MS...
Abstract The nonalcoholic fatty liver disease (NAFLD) is a progressive that affects the health of people in an increasing rate. In current research, we investigated beneficial effect novel probiotic strain L. paracasei Jlus66 (Jlus66) on rats with high‐fat diet (HFD)‐induced NAFLD. intestinal flora was analyzed based V3‐V4 region 16S rDNA sequencing. Moreover, measured oxidative stress and inflammation factors using commercial ELISA kit, lipopolysaccharide (LPS) serum chromogenic end‐point...
Abstract The pharmacokinetic profiles of caffeic acid phenethyl ester (CAPE) and its catechol‐ring fluorinated derivative (FCAPE) were determined in rats after intravenous administration 5, 10 or 20 mg/kg for CAPE FCAPE, respectively. plasma concentrations FCAPE measured using a validated liquid chromatography tandem mass spectrometric method. parameters estimated non compartmental analysis (NCA) biexponential fit. results showed that the area under concentration‐time curve treatment...
Effectively delivering therapeutics for treating brain tumors is hindered by the physical and biological barriers in brain. Even with compromised blood-brain barrier highly angiogenic blood-tumor seen glioblastoma (GBM), most drugs, including nanomaterial-based formulations, hardly reach intracranial tumors. This work investigates sub-5 nm ultrafine iron oxide nanoparticles (uIONP) 3.5 core diameter as a carrier DNA topoisomerase inhibitor 7-ethyl-10-hydroxyl camptothecin (SN38) to treat...
Neuroinflammation is a significant driving force in the pathogenesis and progression of central nervous system (CNS) disorders. Polymethoxylated flavones (PMFs), key lipid-soluble constituents Citri Reticulatae Pericarpium (CRP), exhibit excellent blood-brain barrier permeability anti-inflammatory properties, holding therapeutic potential for CNS However, specific bioactive components effects PMFs treating disorders are not well understood. This study employed comprehensive sequential...
The aim of this study was to examine the effect ACS14, a hydrogen sulfide (H(2)S)-releasing derivative aspirin (Asp), on Asp-induced gastric injury. Gastric hemorrhagic lesions were induced by intragastric administration Asp (200 mg/kg, suspended in 0.5% carboxymethyl cellulose solutions) volume 1 ml/100 g body weight. ACS14 (1, 5 or 10 mg/kg) given 30 min before administration. total area erosions, H(2)S concentration and oxidative stress tissues measured three hours after Asp. Treatment...
Previous studies suggested that probiotics intervention may be one of the methods for preventing and/or treating gastric ulcer.The aim study was to compare preventive effects a spaceflight mutant Lactobacillus reuteri F-9-35 and its wild type on ethanol-induced injury in rats.Forty rats were randomly allocated into five groups: normal group (NOR), ethanol (EtOH), skim milk (MILK), L. (F935) wild-type (WT). The NOR EtOH groups received 1 ml distilled water by daily gavage 14 days. MILK alone,...