A5102773605- Plant Parasitism and Resistance
- Drug-Induced Hepatotoxicity and Protection
- Plant and animal studies
- Metabolomics and Mass Spectrometry Studies
- Mass Spectrometry Techniques and Applications
- Natural Compounds in Disease Treatment
- Plant Diversity and Evolution
- Drug Transport and Resistance Mechanisms
- Cardiovascular Effects of Exercise
- Plant Disease Resistance and Genetics
- Cardiomyopathy and Myosin Studies
- Natural product bioactivities and synthesis
- Advanced biosensing and bioanalysis techniques
- Acupuncture Treatment Research Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Autism Spectrum Disorder Research
- Remote Sensing and Land Use
- Plant Reproductive Biology
- Advanced Proteomics Techniques and Applications
- Metabolism and Genetic Disorders
- Parkinson's Disease Mechanisms and Treatments
- Stress Responses and Cortisol
- HIV, Drug Use, Sexual Risk
- Liver Diseases and Immunity
- HIV/AIDS Research and Interventions
Beijing Chao-Yang Hospital
2019-2022
Capital Medical University
2013-2022
Beijing Institute of Technology
2021
University of North Carolina at Charlotte
2021
Southwest Forestry University
2020
Chinese Academy of Medical Sciences & Peking Union Medical College
2019
Beijing Botanical Garden
2011
South China Botanical Garden
2011
Nanfang Hospital
2005
Southern Medical University
2005
Currently, antidepressants are the dominative treatment for depression, but they have limitations in efficacy and may even produce troublesome side effects. Electroacupuncture (EA) has been reported to therapeutic benefits of depressive disorders. The present study was conducted determine whether EA could enhance antidepressant a low dose citalopram (an SSRI antidepressant) chronic unpredictable stress-induced depression model rats. Here, we show that combined with 2 Hz 5 mg/kg three weeks...
Background Many insects feed on pollen surface lipids and contents accessible through the germination pores. Pollen walls, however, are not broken down because they consist of sporopollenin highly resistant to physical enzymatic damage. Here we report that certain Microlepidoptera chemically dissolve grains with exudates from their mouthparts. Methodology/Principal Findings Field observations experiments in tropical China revealed two species Deltophora (Gelechioidea) exclusive pollinators...
Many genetic variants have been linked to familial or sporadic Parkinson's disease (PD), among which those identified in PARK16, BST1, SNCA, LRRK2, GBA and MAPT genes demonstrated be the most common risk factors worldwide. Moreover, complex gene-gene gene-environment interactions highlighted PD pathogenesis. Compared studies focusing on predisposing effects of genes, there is a relative lack research investigating how these their influence clinical profiles PD. In cohort consisting 2,011...
Amino acid analysis or metabonomics requires large-scale sample collection, which makes storage a critical consideration. However, functional amino acids are often neglected in metabolite stability studies because of the difficulty detecting and accurately quantifying them with most methods. Here, we investigated related amines human serum following different preprocessing pre-storage procedures. Serum samples were collected subjected to three conditions; cold (4°C), room temperature (22°C),...
Abstract Arrhythmogenic cardiomyopathy (ACM) is a familial featured by fibrofatty replacement of cardiomyocytes. Responsible genetic factors are not discernible in approximately one‐third ACM probands. To investigate this further, we performed whole genome sequencing 14 mutation‐negative probands who underwent cardiac transplantation, and identified one proband with rare homozygous missense variant PNPLA2 (c.245G > A, p.G82D), rate‐limiting enzyme that hydrolyzes triglycerides into fatty...
Background: Machine learning has the potential to help researchers better understand and close gap in HIV care delivery large metropolitan regions such as Mecklenburg County, North Carolina, USA. Objectives: We aim identify important risk factors associated with delayed linkage for patients novel machine models high-risk of delay. Methods: Deidentified 2013–2017 County surveillance data eHARS format were requested. Both univariate analyses random forest model (developed R 3.5.0) applied...
We aimed to explore novel biomarkers involved in alterations of metabolism and gene expression related the hepatotoxic effects Tripterygium glycosides tablet (TGT) rats. Rats were randomly divided into groups based on oral administration TGTs for 6 weeks: control, low-dose (9.5 mg/kg), high-dose (18.9 mg/kg). Serum samples total liver RNA subjected metabonomic transcriptomic analyses. Thirteen metabolites significantly up-regulated by injury induced glycosides. Five potential more sensitive...
Background: Many insects feed on pollen surface lipids and contents accessible through the germination pores. Pollen walls, however, are not broken down because they consist of sporopollenin highly resistant to physical enzymatic damage. Here we report that certain Microlepidoptera chemically dissolve grains with exudates from their mouthparts. Methodology/Principal Findings: Field observations experiments in tropical China revealed two species Deltophora (Gelechioidea) exclusive...
Abstract Amino acids analysis or metabonomics requires abundant serum/plasma samples collection and storage has become inevitable given the limited capacity for immediate analysis. Currently, most of existing studies on metabolites stability during sample focused long-term short-term stability, while many functional amino might be ignored due to poor sensitivity detection methods. Here, we attempted elucidate related amines as comprehensive possible in human serum following different...
Abstract Simao pine is one of primary economic tree species for resin and timber production in southwest China, the exploitation utilization are constrained by relatively lacking genetic information. Construction a fine linkage map detecting QTLs growth-related traits an important section molecular breeding program Pine. In our study, high-resolution employing specific locus amplified fragment sequencing (SLAF-seq) with F 1 population has been constructed. There were 11,544 SNPs assigned to...