- Pharmacological Effects of Natural Compounds
- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Analysis
- Pharmacogenetics and Drug Metabolism
- Nanoplatforms for cancer theranostics
- Flavonoids in Medical Research
- Phytochemistry and Bioactivity Studies
- Immune cells in cancer
- Cancer Immunotherapy and Biomarkers
Shenzhen Pingle Orthopedic Hospital
2022-2024
Guangzhou University of Chinese Medicine
2022
Li Chang decoction (LCD), a Chinese medicine formula, is commonly used to treat ulcerative colitis (UC) in clinics.This study aimed identify the major components LCD and its prototype metabolic rat biological samples.The chemical constituents were identified by establishing reliable ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry (UPLC-QTOF/MS) method. Afterwards, rats orally administered LCD, samples (plasma, urine, feces) collected...
Objective. Traditional Chinese medicine (TCM) is an important part of the comprehensive treatment hepatocellular carcinoma (HCC), and materia medica formulas with effect “Yiqi Jianpi” (replenishing qi strengthening spleen) or “Jiedu” (removing toxicity) have been proved to be effective in treating HCC. However, mechanisms these HCC remain unclear. In this paper, our goal explore antitumor activity its molecular Yiqi Jianpi Jiedu (YQJPJD) formula against Methods. The bioactive ingredients...