Jianyuan Kang

ORCID: 0000-0003-1589-1312
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Digestive system and related health
  • Cancer-related molecular mechanisms research
  • Traditional Chinese Medicine Analysis
  • Flavonoids in Medical Research
  • Eosinophilic Esophagitis
  • Cytokine Signaling Pathways and Interactions
  • Caveolin-1 and cellular processes
  • Ginger and Zingiberaceae research
  • Pharmacological Effects of Natural Compounds
  • Galectins and Cancer Biology
  • Advanced Vision and Imaging
  • Image and Video Quality Assessment
  • Inflammatory Bowel Disease
  • Video Coding and Compression Technologies
  • Gastrointestinal disorders and treatments
  • Natural product bioactivities and synthesis
  • Cancer Mechanisms and Therapy
  • IL-33, ST2, and ILC Pathways

Guangzhou University of Chinese Medicine
2022-2024

Shenzhen Pingle Orthopedic Hospital
2020-2023

North China University of Technology
2020

Kaempferol is a natural polyphenol in lots of Chinese herbs, which has shown promising treatment for gastric cancer (GC). However, the molecular mechanisms its action have not been systematically revealed yet. In this work, network pharmacology approach was used to elucidate potential kaempferol GC.The input into PharmMapper and SwissTargetPrediction database get targets, targets GC were obtained by retrieving Online Mendelian Inheritance Man (OMIM) database, MalaCards Therapeutic Target...

10.1155/2020/5891016 article EN cc-by BioMed Research International 2020-10-21

Spasmolytic polypeptide-expressing metaplasia (SPEM) is characterized by mucus cell morphologies at the base of gastric glands, which considered advanced SPEM when accompanied with an increase in transcripts associated intestinal-type cancer. Weiwei decoction (WWD) was modified from "Si-Jun-Zi Tang," has been used for thousands years China against atrophy and metaplasia.To investigate effects potential mechanisms WWD SPEM.Liquid chromatography-mass spectrometry employed to analyze...

10.1016/j.jep.2023.117062 article EN cc-by-nc-nd Journal of Ethnopharmacology 2023-08-19

Intestinal metaplasia (IM) refers to the replacement of gastric epithelial cells by intestinal cells. This is often accompanied chronic atrophic gastritis (CAG), which a precancerous lesion cancer. The incidence rates CAG and IM are increasing gradually, generates an enormous economic burden individuals society. To explore pathogenesis with IM, we screened out differentially expressed gene olfactomedin 4 (OLFM4) bioinformatics constructed OLFM4-shRNA plasmid chitosan magnetic nanoparticles...

10.1166/jnn.2020.18892 article EN Journal of Nanoscience and Nanotechnology 2020-07-26

Objective. Traditional Chinese medicine (TCM) is an important part of the comprehensive treatment hepatocellular carcinoma (HCC), and materia medica formulas with effect “Yiqi Jianpi” (replenishing qi strengthening spleen) or “Jiedu” (removing toxicity) have been proved to be effective in treating HCC. However, mechanisms these HCC remain unclear. In this paper, our goal explore antitumor activity its molecular Yiqi Jianpi Jiedu (YQJPJD) formula against Methods. The bioactive ingredients...

10.1155/2022/8669993 article EN cc-by Computational and Mathematical Methods in Medicine 2022-10-29

BACKGROUND Gastric intestinal metaplasia (IM) is a precancerous lesion that associated with an elevated risk of gastric carcinogenesis. Weiwei Decoction (WWD) promising traditional Chinese herbal formula widely employed in clinical for treating IM. Previous studies suggested the potential involvement olfactomedin 4 (OLFM4)/nucleotide-binding oligomerization domain 1 (NOD1)/caudal-type homeobox gene 2 (CDX2) signaling pathway IM regulation. AIM To verify regulation OLFM4/NOD1/CDX2 IM,...

10.4251/wjgo.v16.i7.3211 article EN World Journal of Gastrointestinal Oncology 2024-07-11

For the virtual reality 360 [Formula: see text] videos, equirectangular projection (ERP) is a commonly used format. However, its high resolution brings extraordinary huge computational complexity in encoding. In order to speed up intra coding process, fast unit (CU) partitioning algorithm based on regional decision tree proposed this paper. The frame image divided into two regions from statistical point of view, and earlysplit pruned trees are established using light weight sample attributes...

10.1142/s0218001420550241 article EN International Journal of Pattern Recognition and Artificial Intelligence 2020-02-21
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