A5010824639- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Stress Responses and Cortisol
- Alcoholism and Thiamine Deficiency
- Botulinum Toxin and Related Neurological Disorders
- SARS-CoV-2 detection and testing
- Cholinesterase and Neurodegenerative Diseases
- SARS-CoV-2 and COVID-19 Research
- Pain Mechanisms and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Cancer Treatment and Pharmacology
- Health disparities and outcomes
- Blood Pressure and Hypertension Studies
- Aging and Gerontology Research
- Nuclear Receptors and Signaling
- COVID-19 Clinical Research Studies
Instituto de Investigaciones Científicas y Servicios de Alta Tecnología
2020-2025
Pennsylvania State University
2024
Alzheimer's Disease and related dementias (ADRD) are an increasing threat to global health initiatives. Efforts prevent the development of ADRD require understanding behaviors that increase decrease risk neurodegeneration cognitive decline, in addition uncovering underlying biological mechanisms behind these effects. Stress exposure alcohol consumption have both been associated with increased for human populations. However, our ability understand causal requires substantial preclinical...
La acumulación irregular de la proteína ?-amiloide (A?), tau hiperfosforilada y neuroinflamación son factores que afectan función neuronal en Enfermedad Alzheimer (EA). asociada a EA podría causar el daño sináptico por sí mismo o exacerbar causado A?. Se ha detectado un aumento citocina CCL1 (I-309) suero sangre periférica personas con Deterioro Cognitivo Leve (DCL) EA, lo se propone puede ser útil como biomarcador diagnóstico del DCL EA. El objetivo general este estudio fue evaluar efecto...
Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of ongoing disease 2019 (COVID-19) pandemic, which has reached 28 million cases worldwide in 1 year. The serological detection antibodies against virus will play a pivotal role complementing molecular tests to improve diagnostic accuracy, contact tracing, vaccine efficacy testing, and seroprevalence surveillance. Here, we aimed first evaluate lateral flow assay's ability identify specific IgM IgG...
There is a dearth of research in Latin America regarding risk and protective factors affecting older adults’ cognition. This study aimed to investigate the mediating association between occupational complexity late-life cognition daily function sample Hispanic adults. Participants ( n = 588) aged 65 years underwent clinical, functional, cognitive assessments. Mediation analyses revealed that depressive symptoms mediated relationship as well functional outcomes. Results provide evidence...