- Sleep and related disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Biological and pharmacological studies of plants
- Essential Oils and Antimicrobial Activity
- Anesthesia and Neurotoxicity Research
- Pharmacological Effects and Toxicity Studies
- Sleep and Wakefulness Research
- Biochemical Analysis and Sensing Techniques
- Family and Patient Care in Intensive Care Units
- Pregnancy and Medication Impact
- Drug-Induced Hepatotoxicity and Protection
- Reproductive System and Pregnancy
- Antioxidant Activity and Oxidative Stress
- Plant Genetic and Mutation Studies
- Cancer Immunotherapy and Biomarkers
- Pelvic floor disorders treatments
- Traditional Chinese Medicine Studies
- Respiratory Support and Mechanisms
- Traditional Chinese Medicine Analysis
- Phytochemistry and Biological Activities
- Bioactive natural compounds
- FOXO transcription factor regulation
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cancer, Stress, Anesthesia, and Immune Response
- Dermatology and Skin Diseases
University of South China
2019-2025
Hefei University of Technology
2025
Hunan Provincial Maternal and Child Health Hospital
2018-2022
Hainan General Hospital
2016
Context: Lutein (LU) is a major carotenoid with various pharmacological activities including anti-inflammatory, antioxidant and anti-apoptosis. Objective: The cardioprotective efficacy of LU was determined by evaluating the biochemical histopathological changes in isoproterenol (ISO) induced myocardial infarction (MI) rat model. Materials methods: Healthy male albino rats (n = 40) were segregated into 4 equal groups. Group I (control) administered olive oil, II orally pre-treated only 40 mg...
Objective This study aims to define the prioritisation of needs for an intelligent robot’s functions in intensive care unit (ICU) from a clinical perspective. Design introduces nominal group technique. Setting uses national setting. Participants includes total 851 respondents 34 provinces China who participated survey. A 12 members was organised by research group; there were seven experts with background critical care, two junior attending physicians and three experienced nurses. Results 50...
Allergic contact dermatitis (ACD) is a common irritability skin disease, which can be cured by using the Chinese patent medicine. To explore pharmacological effect of total flavonoids Fructus Kochiae (FK) on ACD, we used dinitrochlorobenzene‐ (DNCB‐) induced ACD rats. Five groups were in our experiments. The normal group and DNCB treated with 0.5% CMC‐Na; + hFK was high dose FK (200 mg/kg); lFK low (100 Pre prednisolone acetate (2.5 mg/kg). results showed that treatment had significantly...
To study the mechanism of protection provided by dexmedetomidine against COPD-induced lung injury.COPD rat model was determined measuring function, and comparing HE staining between two different groups. We got tissue cells from control COPD The were divided into three groups: group, blank drug groups that rats. Cell apoptosis, relative gene expression TNF-α IL-1β nutrient solution measured.The TV, PEF, EF50, FEV0.3 FEV0.3/FVC in group significantly lower than (1.26±0.17 vs 2.65±0.21;...
Safety of drug use during pregnancy attracts attentions from clinicians, pregnant woman, and even the total society. However, studies about medication followed birth defects (BDs) are rare in Chinese. To study condition BDs Hunan province China, here a cross-sectional was carried out. All women using delivering fetuses with province, 2016 to 2019 were employed this study. The descriptive analysis out Excel 2010, data analyses performed by Chi-Squared test SPSS 16.0. After filtering, 752...
Introduction In this study, we aimed to study the potential role of H2S and application dietary methionine restriction (DMR) in treatment cognitive dysfunction sleep deprived rat models. Material methods The groups were established as a Control group, deprivation (SD) SD + NaSH group DMR group. Behavioral data was studied via Morris water maze test. TUNEL assay, real-time PCR, immunohistochemistry (IHC) enzyme-linked immunosorbent assay (ELISA) performed differences impairment related genes...
Insomnia is a common clinical condition. The Shangxia Liangji formula (SXLJF) classic prescription for treating insomnia. However, the mechanism underlying anti-insomnia effects SXLJF remains unclear. This study aimed to reveal of action through comprehensive approach combining metabolomics, network pharmacology (NP), and experimental verification. First, para-chlorophenylalanine-induced mouse insomnia model was established. Thereafter, differential metabolites were identified using serum...