A5100392356- Gas Sensing Nanomaterials and Sensors
- Analytical Chemistry and Sensors
- Cancer-related molecular mechanisms research
- Advanced Chemical Sensor Technologies
- Cancer, Hypoxia, and Metabolism
- Organic Light-Emitting Diodes Research
- Ubiquitin and proteasome pathways
- Cancer, Lipids, and Metabolism
- Quantum optics and atomic interactions
- Alzheimer's disease research and treatments
- Cancer-related gene regulation
- Organic Electronics and Photovoltaics
- RNA modifications and cancer
- Salivary Gland Disorders and Functions
- Natural product bioactivities and synthesis
- Luminescence and Fluorescent Materials
- Conducting polymers and applications
- Quantum Information and Cryptography
- Estrogen and related hormone effects
- Bone Tissue Engineering Materials
- Circular RNAs in diseases
- Mycobacterium research and diagnosis
- Medicinal Plant Pharmacodynamics Research
- Traditional Chinese Medicine Analysis
- Graphene and Nanomaterials Applications
Smith-Kettlewell Eye Research Institute
2025
Stanford University
2024-2025
Guangzhou Medical University
2020-2024
State Key Laboratory on Integrated Optoelectronics
2005-2024
Jilin University
2013-2024
Stomatology Hospital
2006-2023
Kingmed Diagnostics
2023
University of Pittsburgh
2023
Monash University Malaysia
2022-2023
Guiyang Medical University
2023
Abstract Background Scar formation is a common consequence of skin wound healing, and no effective treatment exists. Umbilical cord blood mesenchymal stem cells (UCB-MSCs) can improve healing; however, the role UCB-MSCs remains unclear whether they ameliorate scar has not been fully elucidated. Methods To determine function UCB-MSCs, we examined compared therapeutic effects UCB-MSC-derived exosomes (UCB-MSC-exo) on healing in rats. Moreover, UCB-MSC-exo-specific miRNAs were identified their...
Wnt/β-catenin signaling has an important role in the angiogenic activity of endothelial cells (ECs). Bach1 is a transcription factor and expressed ECs, but whether regulates angiogenesis unknown. This study evaluated signaling. Hind-limb ischemia was surgically induced Bach1(-/-) mice their wild-type littermates C57BL/6J treated with adenoviruses coding for or GFP. Lack expression associated significant increases perfusion vascular density proangiogenic cytokines ischemic hindlimb mice,...
Abstract Background Long non-coding RNAs (lncRNAs) are tumor-associated biological molecules and have been found to be implicated in the progression of colorectal cancer (CRC). This study aims examine effects lncRNA RP11-468E2.5 its target genes (STAT5 STAT6) on activities CRC cells via Janus kinase-signal transducer activator transcription (JAK/STAT) signaling pathway. Methods We initially screened GEO database for differentially expressed lncRNAs related then made a prediction genes. Then...
Despite the availability of several therapeutic options, a safer and more effective modality is urgently needed for treatment bladder cancer. Costunolide, member sesquiterpene lactone family, possesses potent anticancer properties. In this study, first time we investigated effects costunolide on cell viability apoptosis in human cancer T24 cells. Treatment cells with resulted dose-dependent inhibition induction which was associated generation ROS disruption mitochondrial membrane potential...
Adult wound healing often results in fibrotic scarring that is caused by myofibroblast aggregation. Human amniotic fluid stem cells (hAFSCs) exhibit significantly anti-fibrotic properties during healing. However, it little known whether hAFSCs directly or indirectly (paracrine) contribute to this process. Using the full-thickness skin-wounded rats, we investigated therapeutic potential of hAFSC-derived exosomes (hAFSC-exo). Our showed hAFSC-exo accelerated rate and improved regeneration hair...
By investigating the third-order nonlinearity of a four-level ladder-type atomic system, it is found that, with spontaneously generated coherence (SGC) present, nonlinear absorption or refraction can be significantly enhanced vanishing linear absorption. We attribute enhancement mainly to quantum interference in two decay pathways from upper closely lying levels. With standing-wave trigger field, phase grating, which effectively diffracts weak probe into high-order direction, induced by...
A scheme of two-dimensional (2D) atom localization based on the interference double-dark resonances is proposed, in which N-type interacts with two orthogonal standing-wave fields. Because spatial-dependent atom–field interaction, 2D can be realized via measuring upper state population or probe absorption. We obtain that maximum probability finding an at a particular position wavelength domain (λ1×λ2) 1/2 when localized intersection antinodes quadrants I and III plane. This shows more...
A scheme for two-dimensional (2D) subwavelength atom localization is proposed, in which the a four-level tripod configuration and driven by two orthogonal standing-wave lasers. Because of spatial dependence atom-field interaction, spontaneously emitted photon carries information about position fields. We exploit this fact to 2D conditioned on measurement at particular frequency, obtain high precision resolution probability distribution. Moreover, an improvement factor 2 detecting can be...
Isoalantolactone, a medicinal plant-derived natural compound, is known to induce apoptosis in various cancer cell lines. However, its effect on prostate cells has not been addressed. Thus, we examined the effects of isoalantolactone cells. It was found that inhibits growth both androgen-sensitive (LNCaP) as well androgen-independent (PC3 and DU-145) dose-dependent manner. Furthermore, our results indicate isoalantolactone-induced PC3 associated with generation ROS dissipation mitochondrial...
Chemotherapy as a conventional cancer treatment suffers from critical systemic side effects, which is generally considered the consequence of reactive oxygen species (ROS). Fullerenes have been widely studied for their excellent performance in radicals scavenging. In present study, we report solid-liquid reaction to synthesize fullerenols and application ROS scavengers chemotherapy protection. The carried out without catalyst suitable mass production. novel [60]/[70] show high stability...
Background: Pulmonary fibrosis (PF) is a terminal pathological change in variety of lung diseases characterized by excessive deposition extracellular matrix, for which effective treatment lacking. Tangeretin (Tan), flavonoid derived from citrus, has been shown to have wide range pharmacological effects. This study aimed investigate the role and potential mechanisms Tan on pulmonary fibrosis. Methods: A model was established administering bleomycin through tracheal drip, followed or...