- Molecular Sensors and Ion Detection
- Chemical synthesis and alkaloids
- Essential Oils and Antimicrobial Activity
- Asymmetric Synthesis and Catalysis
- Analytical Chemistry and Sensors
- Sesquiterpenes and Asteraceae Studies
- Phytochemistry and Biological Activities
- Cyclopropane Reaction Mechanisms
- Electrochemical Analysis and Applications
- Neuroscience and Neuropharmacology Research
- Phytochemicals and Antioxidant Activities
- Plant biochemistry and biosynthesis
- Coordination Chemistry and Organometallics
- Pharmacological Receptor Mechanisms and Effects
- Plant and animal studies
- Synthesis and Reactivity of Heterocycles
- Synthesis of Organic Compounds
- Synthesis and Properties of Aromatic Compounds
- Analytical chemistry methods development
- Phenothiazines and Benzothiazines Synthesis and Activities
- Bioactive Compounds and Antitumor Agents
- Chemical Reactions and Mechanisms
- X-ray Diffraction in Crystallography
- Catalytic C–H Functionalization Methods
- Carbohydrate Chemistry and Synthesis
University of Crete
2009-2024
Crete University Press
2015-2024
Université de Montpellier
2007
National and Kapodistrian University of Athens
2004
Foundation for Research and Technology Hellas
1994
New York University
1986
The synthesis and spectral profile of a "turn-on" fluorescent sensor selective for Hg2+ ions in aqueous media is described.
The present work is the first report on ingredients of P. × commixta hybrid, a plant genus Phlomis. So far, thirty substances have been isolated by various chromatographic techniques and identified spectroscopic methods, such as UV/Vis, NMR, GC-MS LC-MS. compounds are classified flavonoids: naringenin, eriodyctiol, eriodyctiol-7-O-β-D-glucoside, luteolin, luteolin-7-O-β-D-glucoside, apigenin, apigenin-7-O-β-D-glucoside, diosmetin-7-O-β-D-glucoside, quercetin, hesperetin...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereocontrolled total synthesis of lipoxins AK. C. Nicolaou, A. Veale, S. E. Webber, and H. KaterinopoulosCite this: J. Am. Chem. Soc. 1985, 107, 25, 7515–7518Publication Date (Print):December 1, 1985Publication History Published online1 May 2002Published inissue 1 December 1985https://pubs.acs.org/doi/10.1021/ja00311a048https://doi.org/10.1021/ja00311a048research-articleACS PublicationsRequest reuse permissionsArticle...
The elaboration of novel techniques for flavonoid intracellular tracing would elucidate the compounds' absorption and bioavailability assist molecular pharmacological approaches, as they are promising candidates drug development. This study exploited properties quercetin (3,3',4',5,7-pentahydroxyflavone), found in high concentrations majority edible plants. Through use UV−vis spectroscopy, confocal microscopy, HPLC-ESI-MS, native quercetin, at physiologically relevant concentrations, was to...
BNN27, a C17-spiroepoxy derivative of DHEA, was shown to have antiapoptotic properties via mechanisms involving the nerve growth factor receptors (tropomyosin-related kinase A [TrkA]/neurotrophin receptor p75 [p75NTR]). In this study, we examined effects BNN27 on neural/glial cell function, apoptosis, and inflammation in experimental rat streptozotocin (STZ) model diabetic retinopathy (DR). The ability activate TrkA regulate p75NTR expression investigated. (2,10, 50 mg/kg i.p. for 7 days)...
Total syntheses and spectral properties of fluorescent Pb2+ indicators are reported.
Ceratonia siliqua L., commonly known as the carob tree, appears in most Mediterranean countries, often cultivated for collection of its fruits to be used food humans and animals. This study was aimed at phytochemical characterization two common Cretan C. cultivars biological evaluation deseeded pod seed extracts regarding their putative use cosmetics. Gas liquid chromatographic techniques were assess essential oil, fatty acid, carbohydrate profiles. Cell-free assays, including free-radical...
A series of coumarin analogs, designed and synthesised as potential fluorescent zinc probes were evaluated for their biological activity anti-inflammatory antioxidant agents. The effect the compounds on inflammation, using carrageenin-induced rat paw oedema model, was studied. In general, found to be potent agents (26.5–64%). Compound 5 interact significantly with 1,1-diphenyl-2-picryl-hydrazyl stable free radical (DPPH) whereas remainder inactive in this assay. inhibit general soybean...
Costic acid has been isolated from the plant Dittrichia viscosa and its efficacy against Varroa destructor, a parasite of Apis mellifera, European honey bee, studied. exhibited potent in vivo acaricidal activity parasite. Initial experiments showed that compound is not toxic for human umbilical vein endothelial cells (HUVEC) at concentrations up to 230 micromolar (μM), indicating costic could be used as safe, low-cost efficient agent controlling varroosis bee colonies.
The synthesis and spectral profile of a cyclam-type “turn on” fluorescent sensor selective for Hg2+ ions in aqueous media is described. Its properties are compared to those second probe with an N-deprotected cyclam system. vast difference ion selectivity between the two sensors reveals influence functional group modifications on probes.
ABSTRACT The chemical composition of the essential oil leaves Cistus creticus L., (Fam. Cistaceae), was investigated by GC/MS. Among 49 components identified, (representing 76.56% composition) diterpenes (59.59%) predominated. major were manoyl oxide (19.61%) and 13-epi-manoyl (13.44%). C. found to exhibit a strong antibacterial activity against Gram + bacteria.
Abstract A coumarin derivative with a malonate unit has been synthesized and used for the preparation of fullerene–coumarin dyad through Bingel cyclopropanation method. The newly is soluble in organic solvents fully characterized traditional spectroscopic techniques. Electronic interactions between two components were probed aid UV/Vis spectroscopy, fluorescence emission, electrochemistry measurements. Our studies clearly show presence electronic C 60 modified ground state; efficient...