The purpose of this study was to investigate the topographic relationship between decreased parapapillary retinal microvasculature as assessed by optical coherence tomography angiography (OCTA) and nerve fiber layer (RNFL) defect in eyes with primary open-angle glaucoma (POAG) a localized RNFL defect.The peripapillary circulation evaluated using OCTA centered on optic head 98 POAG having 45 healthy control eyes. A vascular impairment (VI) identified presence sign indicating microvasculature....

Purpose: To compare the capability of lamina cribrosa depth (LCD) and (LC) curvature in discriminating between eyes with primary open-angle glaucoma (POAG) healthy eyes. Methods: Seventy-seven 77 patients POAG subjects who were matched for age, sex, axial length included. The LCD index (LCCI) measured B-scan images obtained using swept-source optical coherence tomography at seven locations spaced equidistantly across vertical optic disc diameter. mean values measurements made points LC...

Purpose: The purpose of this article was to compare the frequencies parapapillary deep-layer microvasculature dropout (MvD) detected by optical coherence tomography angiography in eyes with primary open-angle glaucoma (POAG) and healthy determine topographic correlation between MvD glaucomatous retinal nerve fiber layer (RNFL) defect POAG eyes. Methods: Microvasculature peripapillary evaluated 150 patients 45 controls using swept-source identify an MvD. Frequencies MvDs were compared control...

To investigate whether the lamina cribrosa (LC) curvature is decreased after trabeculectomy.Thirty-nine eyes of 39 patients with primary open-angle glaucoma who underwent trabeculectomy were included. Optic nerves scanned by using enhanced-depth-imaging spectral-domain optical coherence tomography before and trabeculectomy. The LC was assessed measuring index (LCCI) in seven horizontal B-scan images each eye.The LCCI significantly smaller at postoperative 6 months than preoperative level all...

To characterize the microstructure underlying parapapillary deep-layer microvasculature dropout (MvD) identified by optical coherence tomography (OCT) angiography (OCTA) in eyes with primary open-angle glaucoma (POAG).Parapapillary MvD was defined as a focal sectoral capillary without any visible microvascular network en face images obtained using swept-source OCTA. The peripapillary characterized 188 POAG patients deep layer. Twelve radial optic nerve were OCT to examine structure and...

Purpose: To investigate the choroidal thickness changes after intravitreal bevacizumab injection (IVB), panretinal photocoagulation (PRP) or both for diabetic retinopathy treatment.Materials and Methods: The study included 31 eyes (31 patients) in IVB group, 35 (35 PRP group IVB–PRP group. Enhanced depth imaging optical coherence tomography (EDI-OCT) was performed before 1 month each treatment to measure subfoveal extrafoveal (500 1000 μm) thicknesses. best-corrected visual acuity (BCVA)...

Purpose To investigate the topographic relationship between parapapillary deep-layer microvasculature dropout (MvD) as assessed by optical coherence tomography (OCT) angiography (OCTA) and juxtapapillary choroidal thickness (JPCT) in primary open-angle glaucoma (POAG). Methods A total of 194 eyes (138 POAG 56 control eyes) having atrophy (PPA) were imaged using swept-source OCT OCTA to examine microstructure PPA measure JPCT, determine presence MvD. MvD was defined a focal sectoral capillary...

Precis: Parapapillary choroidal microvasculature dropout (MvD), as observed by optical coherence tomography (OCT) angiography, was useful to detect glaucomatous damage in highly myopic eyes with unreliable OCT results due segmentation errors. Purpose: The purpose of this study evaluate the usefulness angiography (OCTA) imaging peripapillary detecting eyes, cases where evaluating thickness retinal nerve fiber layer (RNFL) is Materials and Methods: Forty-five primary open-angle glaucoma (POAG)...

Background/aims To determine the usefulness of peripapillary retinal vessel density (VD) measured using optical coherence tomography (OCT) angiography (OCTA) in evaluation glaucomatous visual field damage highly myopic eyes with primary open-angle glaucoma (POAG). Methods This cross-sectional observational study enrolled a total 124 POAG consisting 40 showing segmentation error (SE) OCT scans and 84 without an SE. The VD, circumpapillary nerve fibre layer thickness (RNFLT) sensitivity loss...

(1) Background: To compare optic nerve sheath diameter (ONSD) in normal-tension glaucoma (NTG) and healthy eyes to investigate the association between ONSD lamina cribrosa (LC) morphology. (2) Methods: This cross-sectional study included 69 NTG matched for age, axial length, intraocular pressure. The LC curvature index (LCCI) was measured from horizontal Cirrus HD-OCT B-scan images five uniformly divided positions vertically of nerve. average LCCI defined as mean measurements at these...

The optic disc pit (ODP) has been considered a region of localized susceptibility to the damage glaucoma.To determine whether rate retinal nerve fiber layer (RNFL) thinning differs according presence and structural characteristics an ODP in primary open-angle glaucoma.We performed prospective case-control study that included 163 eyes with glaucoma (83 80 without ODP) from Glaucoma Clinic Seoul National University Bundang Hospital. Participants were enrolled ongoing Investigating Progression...

To investigate the retinal nerve fiber layer (RNFL) thickness concordance when measured by spectral domain (SD) and swept source (SS) optical coherence tomography (OCT), to compare glaucoma-discriminating capability.RNFL thicknesses were with scan circle, centered on optic head, in 55 healthy, 41 glaucoma suspected, 87 glaucomatous eyes. The RNFL SD-OCT (sdRNFL thickness) SS-OCT (ssRNFL compared using t-test. Bland-Altman analysis was performed examine their agreement. We areas under...

Purpose: The purpose of this study was to investigate whether the lamina cribrosa (LC) curve changes in response intraocular pressure (IOP) reduction following administration topical ocular hypotensive eye drops eyes with normal tension glaucoma (NTG). Methods: Ninety-three 93 patients treatment naïve NTG at initial examination and ≥20% from baseline IOP were included. Serial horizontal B-scan images optic nerve head (ONH) obtained each using enhanced depth imaging spectral domain optical...

Although normal-tension glaucoma (NTG) is pathogenetically heterogenous, there have been few attempts to subclassify NTG patients according the mechanism and anatomy of optic nerve damage. This cross-sectional study was performed investigate differences in clinical ocular characteristics between patient groups stratified degree posterior lamina cribrosa (LC) curve which assessed by calculating LC curvature index (LCCI). A total 101 eyes treatment naïve were included. The head imaged using...

Abstract Focal lamina cribrosa (LC) defects have been found to play an important role in the development and progression of glaucomatous optic neuropathy. However, mechanism generation focal LC is largely unknown. This cross-sectional study was performed investigate curvature frequency parapapillary choroidal microvascular dropout (MvD) eyes with defects. conducted by a retrospective review patients primary open-angle glaucoma (POAG) included ongoing prospective being at Seoul National...

To determine the factors associated with retinal nerve fiber layer (RNFL) loss in eyes acute primary angle-closure (APAC), particularly focusing on influence of change anterior lamina cribrosa surface depth (LCD).After initial presentation, 30 unilateral APAC were followed up at following specific time points over a 12-month period: 1 week, 1~2 months, 2~3 5~6 and 11~12 months. These follow-ups involved intraocular pressure measurements, enhanced depth-imaging spectral-domain optical...

Given that posterior bowing of the lamina cribrosa (LC) is a principle event in development glaucomatous damage, assessment LC morphology may have clinical utility diagnosing and managing glaucoma patients. curvature has been suggested as an index to evaluate morphology. To apply practice, it necessary know normal profiles healthy population. This study was performed investigate characteristics eyes using enhanced depth imaging spectral-domain optical coherence tomography total 250 125...

To describe the parapapillary choroidal microvasculature dropout (CMvD) in glaucomatous eyes without β-zone atrophy (β-PPA) and compare its characteristics with that of CMvD β-PPA.Peripapillary was evaluated on en face images obtained using optical coherence tomography angiography. defined as a focal sectoral capillary no visible microvascular network identified layer. Peripapillary optic nerve head structures, including presence β-PPA, peripapillary thickness lamina cribrosa curvature index...

Purpose: The purpose of this study was to investigate changes in lamina cribrosa (LC) depth after trabeculectomy myopic eyes using enhanced imaging (EDI) spectral-domain optical coherence tomography (SD-OCT). Methods: Serial horizontal B-scans the optic nerve head 41 with primary open-angle glaucoma (POAG) were obtained before and 3 months EDI SD-OCT. LC depth, defined as distance from opening plane Bruch's membrane level anterior surface, measured at 7 locations spaced equidistantly across...

Purpose: The purpose of this study was to characterize the microstructure deep optic nerve tissues in eyes with superior segmental hypoplasia (SSOH) comparison that primary open-angle glaucoma (POAG). Methods: Thirty-five SSOH, 37 POAG, and 54 healthy control underwent enhanced depth imaging (EDI) volume scanning using spectral-domain optical coherence tomography (SD-OCT). POAG patients were matched SSOH terms thickness neuroretinal rim retinal fiber layer sector. lamina cribrosa (LCT)...

중심장액맥락망막병증에서 다른 눈의 중심와아래 맥락막 두께 이승현⋅정혜원⋅김형찬 건국대학교 의학전문대학원 안과학교실 목적: 중심장액맥락망막병증(CSC)에서 스펙트럼 도메인 빛간섭단층촬영의 Enhanced Depth Imaging (EDI-OCT)을 이용하여 이환되 지 않은 두께를 알아보고자 하였다.대상과 방법: CSC환자 30명, 정상 28명을 대상으로 양안의