A5013252301- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Pleural and Pulmonary Diseases
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Cancer Diagnosis and Treatment
- Cardiac tumors and thrombi
- Salivary Gland Tumors Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Bacterial Identification and Susceptibility Testing
- Medical Imaging Techniques and Applications
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Lung Cancer Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Soft tissue tumor case studies
- Airway Management and Intubation Techniques
- Congenital Diaphragmatic Hernia Studies
- Occupational and environmental lung diseases
- Asthma and respiratory diseases
- Gastrointestinal disorders and treatments
- Trauma Management and Diagnosis
- Esophageal and GI Pathology
- Oral and Maxillofacial Pathology
- Transplantation: Methods and Outcomes
- Radiomics and Machine Learning in Medical Imaging
Seirei Mikatabara General Hospital
2016-2025
Tokyo Metropolitan University
2023
Osaka Metropolitan University
2023
Osaka City University
2012-2022
Osaka City University Hospital
2019-2020
Creative Commons
2020
Committee on Publication Ethics
2020
Toneyama National Hospital
2017
Sapporo City General Hospital
2017
Tokyo National Hospital
2017
Cigarette smoking-induced oxidative stress is known to be a key mechanism in COPD pathogenesis. Nuclear factor erythroid 2-related 2 (Nrf2) central transcription that regulates the antioxidant defense system. The aim of this study was compare Nrf2 expression subjects and control subjects, determine role protecting against stress-induced apoptosis. We enrolled 8 7 study. performed bronchial brushing by bronchoscopy obtained epithelial cells from airways. evaluated real-time PCR Western...
Postoperative recurrence is a significant problem in patients with early-stage non-small cell lung cancer (NSCLC), rates of 35% for stage IB and 50% IIA. This study aimed to evaluate the efficacy tegafur-uracil (UFT) as an adjuvant therapy NSCLC poor prognostic factors. A retrospective analysis was conducted 330 IB/IIA who underwent resection between 2000 2019. Patients were divided into two groups based on presence factors (vascular, lymphatic, or pleural invasion high pathological grade)....
Secondary pneumothorax with interstitial lung disease (ILD) is often difficult to treat in comparison primary pneumothorax. The purpose of this study was analyze the actual management and outcome, find most effective treatment.Among 180 patients caused by ILD, who were managed between January 2000 April 2021, 129 included. Fifty-one observation only excluded. In present study, a patient considered be cured if their chest tube could removed.The managements included drainage alone (n=41),...
Objective Hemorrhagic pneumonia due to Stenotrophomonas maltophilia (SM) in severely immunocompromised patients has a very poor prognosis. However, the risk factors for hemorrhagic are not clear. Methods This study assessed predictive of caused by SM. The medical records admitted Osaka City University Hospital with SM bacteremia between January 2008 and December 2017 were retrospectively reviewed. Patients All who had positive blood cultures included this study. They categorized into two...
To plan a surgical approach and predict the operative time or bleeding volume, it is important to determine presence of pleural adhesions before surgery. Dynamic chest radiography (DCR) new modality that can dynamically capture X-rays, we assessed utility DCR for detecting preoperatively.The subjects this study were those who underwent surgery from January 2020 May 2022. The preoperative evaluation was performed by three imaging analysis modes, adhesion defined as spreading more than 20%...
The present study compared the utility of fluorodeoxyglucose-positron emission tomography (FDG-PET) and computed (CT) for predicting pathological response prognosis following neoadjuvant therapy locally advanced non-small-cell lung cancer (NSCLC).This retrospective analysis included 72 patients in whom adjacent structures showed involvement and/or cN2 NSCLC who received induction chemoradiotherapy (ICRT) subsequent surgery at our hospital from 2008 to 2019. FDG-PET CT were performed all...
We report a 75-year-old man with multiple recurrent black papules involving his entire body. In the course of 3 years, 20 lesions were resected, which histologically confirmed as intravascular papillary endothelial hyperplasia (IPEH). A similar vascular lesion was found on tibia. The occurrence IPEH affecting skin and bone is extremely rare. patient's medical history included hepatitis C, hepatoma associated coagulopathy. suggest that this induced by microthrombus formation due to liver dysfunction.
A 72-year-old Japanese man who had undergone resection of a left upper lung carcinoma developed chronic empyema with bronchopleural fistula and destroyed 12 years after surgery. Open-window thoracotomy bronchial occlusion an endoscopic Watanabe spigot (EWS) were performed to control infection. However, the EWS was easily dislodged due remarkable deformation, he experienced repeated episodes pneumonia. We extensive filling N-butyl-2-cyanoacrylate. Stable achieved, there no recurrence...
Objective Baloxavir marboxil is a novel anti-influenza drug reported to have an early antiviral effect, although it also causes the appearance of variant viruses with reduced susceptibility baloxavir. In Japan, four neuraminidase inhibitors (NAIs) been commonly used treat patients influenza. clinical practice, differences in effects baloxavir and NAIs not sufficiently examined. Our objective was clarify efficacy between NAIs. Methods A multicenter, observational study conducted using...
With the advent of high-resolution chest imaging, number patients diagnosed with multiple primary lung cancers is increasing. For treatment cancers, a surgical procedure that preserves pulmonary function while ensuring curability required.The study population included 85 synchronous cancer who received resection between January 2010 and September 2020. Patients within same lobe were excluded, only ≥2 involved lobes included. The postoperative was examined at 3-6 months after...
Bronchiolar adenoma (BA)/ciliated muconodular papillary tumor (CMPT) is defined as a benign composed of epithelial and basal cells. Recently, some cases with driver mutations or malignant transformation have been observed. Thus, whether BA/CMPT remains controversial. We herein report an extremely rare case 68-year-old woman CMPT accompanied by adenocarcinoma in situ (AIS). existed inside the AIS. The component did not show any mutations; however, AIS had EGFR mutation exon 19. accumulation...
Micronodular thymoma with lymphoid stroma is a rare subtype of thymoma. Here we report case micronodular that was completely resected after incomplete resection 10 years earlier. A 70-year-old Japanese woman who had undergone for thymic cyst earlier found to have solid nodule multilocular lesion at the site previous operation. We suspected tumor malignant and performed trans-sternal radical thymectomy diagnosed as pathologically. When reassessed been earlier, few lesions were in wall. Based...
Left sleeve pneumonectomy is a challenging operation that requires individualized approaches. Here, we present new minimally invasive combined thoracoscopic approach.A 61-year-old woman was diagnosed with tracheobronchial adenoid cystic carcinoma. The tumor originated from the left main stem bronchus, and carinal involvement observed. We judged complete resection would be possible via pneumonectomy. However, because esophagus descending aorta suspected, evaluation of resectability in advance...
Good's syndrome (GS) is characterized by immunodeficiency, and can lead to severe infection, which the most significant complication. Although Mycobacterium rarely causes infection in patients with GS, disseminated nontuberculous mycobacterial (NTM) frequently occurs GS that are also positive for human immunodeficiency virus (HIV) or anti-interferon (IFN)-γ autoantibodies. Here, we report a rare case of NTM without HIV IFN-γ A 57-year-old Japanese male myasthenia gravis (treated prednisolone...
Abstract Background Solitary fibrous tumor of the pleura (SFTP) is a mesenchymal tumor, and computed tomography typically shows SFTPs as well-defined lobulated masses. We herein report case SFTP with cystic degeneration entire tumor. Case presentation The patient was 67-year-old Japanese man who referred to our hospital for an abnormal shadow on chest X-ray. Computed showed 9-cm in lower left lobe, small nodules aggregated cyst. Pulmonary aspergillosis suspected, basal segmentectomy...
Pulvinotomy was performed on 42 cases with intractable pain. 19 survived for more than 1 year, the results were classified as follows: 4 excellent, good, 5 fair, and poor. The effects of operation are discussed based disease. 2 cases, who suffered from pain due to infiltration or metastasis cancer, they died 22 14 months after operation, respectively, but had no during year before death. underwent CVD year. Results 3 excellent; These followed up 3-10 years average about years. After atypical...
Abstract Background After the A/H1N1 influenza pandemic in 2009, two new drugs against virus, laninamivir and peramivir, were released 2010 Japan. We investigated current usage effectiveness of medications factors related to time taken alleviate fever. Methods Patients diagnosed with during 2012‐2013 season Osaka Prefecture answered a postcard questionnaire that collected data regarding their demographic characteristics, flu vaccination status, symptoms, prescribed drugs, drug‐related...