- Lung Cancer Diagnosis and Treatment
- Organic Light-Emitting Diodes Research
- Luminescence and Fluorescent Materials
- S100 Proteins and Annexins
- Cell Adhesion Molecules Research
- Traumatic Brain Injury Research
- Transcranial Magnetic Stimulation Studies
- Dysphagia Assessment and Management
- Vagus Nerve Stimulation Research
- Medical Imaging and Pathology Studies
- Lung Cancer Treatments and Mutations
- COVID-19 Clinical Research Studies
- Heart Rate Variability and Autonomic Control
- Cardiac Arrest and Resuscitation
- Neuroscience of respiration and sleep
- Acute Ischemic Stroke Management
- Cancer-related molecular mechanisms research
- Tracheal and airway disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Sleep and Wakefulness Research
- Estrogen and related hormone effects
- Organic Electronics and Photovoltaics
- RNA modifications and cancer
- Spinal Cord Injury Research
- RNA Research and Splicing
Nanchang University
2013-2025
Jiangxi Provincial People's Hospital
2025
First Affiliated Hospital of Nanchang University
2013-2024
First Affiliated Hospital of Jiangxi Medical College
2023-2024
Fudan University
2023-2024
San’an Optoelectronics (China)
2023-2024
Huashan Hospital
2023-2024
Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine
2024
Jiangxi Mental Health Center
2024
Shandong Provincial Hospital
2012-2023
Abstract Background: Among discharged COVID-19 patients, the health-related quality of life is poor, and patients suffer from significant physical psychological impairment. This study was designed to investigate effects Liuzijue exercise on rehabilitation patients. Methods: Thirty three eligible with were enrolled in after discharge. All participants practiced once per day for 20 minutes over 4 weeks. Data collected at baseline end intervention. Primary outcomes involved functional capacity...
Background: Traumatic Brain Injury (TBI) has high disability and mortality rate. Oxidative stress ferroptosis are important pathophysiological characteristics after TBI. Orexin-A (OXA) can alleviate neuronal damage in diverse neurological disorders. Nevertheless, the role mechanism of OXA TBI stay unknown. Objectives: The research investigated protection influence on its potential mechanisms. Methods: Male Sprague-Dawley rats were randomly grouped into: sham, TBI, + normal saline (NS)...
Background and Purpose: Pain is one of the most common symptoms in patients after stroke. It a distressing experience that affects patients' quality life, it highly prevalent clinical practice. The pathogenesis mechanisms PSP are not so clear, there currently lack effective medical treatments, hence necessary to establish sufficient understanding this disease. Limited number studies have applied bibliometric methods systematically analyze on post-stroke pain. This study aimed scientific...
Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Oxidative stress, inflammation, apoptosis are vital pathophysiological features post-TBI.Research has shown that vagus nerve stimulation (VNS) can attenuate oxidative stress in various diseases. However, the critical role VNS TBI still not completely understood. This study investigated protective effects potential mechanism on TBI.Male Sprague-Dawley rats were randomized into 3 groups: sham, TBI, + VNS. The...
Traumatic brain injury (TBI) and its resulting complications pose a major challenge to global public health, in increased rates of disability mortality. Cerebrovascular dysfunction is nearly universal TBI cases closely associated with secondary after TBI. Transcranial direct current stimulation (tDCS) shows great potential the treatment TBI; however, exact mechanism remains elusive. In this study, we performed vivo vitro experiments explore effects mechanisms tDCS controlled cortical impact...
Behavioral assessment based on external manifestations of consciousness fails for patients with cognitive motor dissociation (CMD). Functional near-infrared spectroscopy (fNIRS) is an emerging neuroimaging technique that can detect internal brain functional activities. However, the extent to which fNIRS help identify CMD among those disorders (DOC) remains unclear. To DOC using a command-driven hand-open-close imagery task. was used measure hemodynamic responses 70 prolonged patients,...
Abstract Low-intensity focused ultrasound is a type of that primarily relies on cavitation and mechanical effects. It non-invasive, transient, well tolerated. Previous studies have confirmed low-intensity can reduce neuroinflammation after traumatic brain injury exert neuroprotective However, whether it also induce angiogenesis neurogenesis in the brain, as underlying mechanisms, remains unclear. In this preclinical study, rat model was established using controlled cortical impact device....
Orexins, produced in the lateral hypothalamus, are important neuropeptides that participate sleep/wake cycle, and their expression coincides with projection area of vagus nerve brain. Vagus stimulation has been shown to decrease amounts daytime sleep rapid eye movement epilepsy patients traumatic brain injury. In present study, we investigated whether promotes wakefulness affects orexin expression. A rat model injury was established using free fall drop method. stimulated group, rats...
Abstract Background A growing body of evidence has proven that long noncoding ribonucleic acids (lncRNAs) are important epigenetic regulators play crucial parts in the pathogenesis human cancers. Previous studies have shown intergenic nonprotein coding RNA 01116 (LINC01116) is a carcinogen several carcinomas; however, its function lung adenocarcinoma (LUAD) not been clarified. Here, we aimed to investigate role LINC01116 LUAD. Methods The relative expression levels LUAD cell lines and...
The Xpert MTB/XDR assay met the critical need for etiologic diagnosis of tuberculosis and rifampin resistance in previous studies. However, its benefits tailoring treatment regimen improving outcome patients with rifampin-resistant (RR-TB) require further investigation. In this study, was used to determine profile second-line drugs RR-TB two registered multicenter clinical trials, TB-TRUST (NCT03867136) TB-TRUST-plus (NCT04717908), aim testing efficacy all-oral shorter regimens China....
Abstract Background The aim of this study was to analyze the effect paclitaxel on apoptosis esophageal cancer cells in relation MUC20. Methods RT‐qPCR analysis, a CCK‐8 assay, western blotting, and flow cytometry were used anticancer effects treatment or OE‐MUC20 vitro vivo. Results results showed that significantly induced MUC20 upregulation decreased cell viability increased mTOR signaling activation apoptosis. In addition, PKM2, key downstream molecule signaling, similarly significant...
The exact mechanisms associated with secondary brain damage following traumatic injury (TBI) remain unclear; therefore, identifying the critical molecular involved in TBI is essential. mRNA expression microarray GSE2871 was downloaded from Gene Expression Omnibus (GEO) repository. comprises a total of 31 cerebral cortex samples, including two post-TBI time points. features eight control and seven 4 hours post-TBI, samples 24 post-TBI. In this bioinformatics-based study, 109 66 differentially...
Background: Traumatic brain injury (TBI) is a serious hazard to human health and characterized by high rates of disability mortality. It necessary explore new effective treatment methods reduce the impact TBI on individuals society. As an emerging neuromodulation technique, ultrasound used treat some neurological diseases, but neuroprotective mechanism low-intensity focused (LIFUS) in remains unclear. We aimed investigate protective effects potential mechanisms LIFUS TBI. Methods: A rat...
Esophageal squamous cell carcinoma (ESCC) is one of the most common types malignancies globally. Forkhead box M1 (FOXM1) has important functions in cancer progression. However, function FOXM1 signaling ESCC remains unknown. The aim present study was to evaluate expression level and human ESCC. first detected 78 cases primary tissues matched normal tissue samples by immunohistochemistry, western blot analysis reverse transcription-quantitative polymerase chain reaction. Subsequently,...
This study aimed to evaluate the current research hotspots and development tendency of Transcranial Direct Current Stimulation (tDCS) in field neurobiology from a bibliometric perspective by providing visualized information scientists clinicians. Publications related tDCS published between 2000 2022 were retrieved Web Science Core Collection (WOSCC) on May 5, 2022. Bibliometric features including number publications citations, citation frequency, H-index, journal impact factors, reports...
Experiments were performed to determine the effect of roasting whole wheat flours at 80 °C, 100 °C and 120 for 30 min on four forms phenolics, Maillard reaction products (MRPs), DPPH scavenging activity (DSA) 15, 45 days after flowering (15-DAF, 30-DAF, 45-DAF). Roasting increased phenolic content antioxidant flours, which dominant contributions formation products. The highest total (TPC) DSA (TDSA) determined in DAF-15 °C/30 min. exhibited browning index fluorescence free intermediate...