- Advanced biosensing and bioanalysis techniques
- Gold and Silver Nanoparticles Synthesis and Applications
- Biosensors and Analytical Detection
- Electrochemical sensors and biosensors
- Conducting polymers and applications
- Advanced Nanomaterials in Catalysis
- Electrochemical Analysis and Applications
- Molecular Sensors and Ion Detection
- Supercapacitor Materials and Fabrication
- Plant biochemistry and biosynthesis
- Nanocluster Synthesis and Applications
- Analytical Chemistry and Sensors
- Luminescence and Fluorescent Materials
- Spectroscopy Techniques in Biomedical and Chemical Research
- Advanced Photocatalysis Techniques
- Nanomaterials for catalytic reactions
- Advancements in Battery Materials
- Nerve injury and regeneration
- Graphene research and applications
- Traditional Chinese Medicine Analysis
- Advanced Sensor and Energy Harvesting Materials
- Quantum Dots Synthesis And Properties
- Advanced Fluorescence Microscopy Techniques
- Analytical chemistry methods development
- Covalent Organic Framework Applications
South China University of Technology
2017-2025
Cell Technology (China)
2020-2025
China Academy of Chinese Medical Sciences
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2023
Shaanxi Normal University
2011-2023
China Agricultural University
2022
Chengdu University of Traditional Chinese Medicine
2022
National Research Center for Rehabilitation Technical Aids
2021-2022
Taizhou People's Hospital
2021
Nantong University
2021
Abstract Tanshinones are the bioactive nor -diterpenoid constituents of Chinese medicinal herb Danshen ( Salvia miltiorrhiza ). These groups chemicals have characteristic furan D-ring, which differentiates them from phenolic abietane-type diterpenoids frequently found in Lamiaceae family. However, how 14,16-epoxy is formed has not been elucidated. Here, we report an improved genome assembly using a highly homozygous genotype. We identify cytochrome P450 (CYP71D) tandem gene array through...
Monodisperse silica particles (SiPs) were surface-modified with a newly designed reversible addition–fragmentation chain transfer (RAFT) agent having triethoxysilane moiety, 6-(triethoxysilyl) 2-(((methylthio)carbonothioyl)thio)-2-phenylacetate (EHT). Surface-initiated RAFT polymerization of styrene was carried out the EHT-modified SiPs in presence free agent. The proceeded living manner, producing coated well-defined polystyrene target molecular weight graft density as high 0.3 chains/nm2....
A novel graphene-based electrochemical filter with carbon nanotubes as conductive binders was developed for water purification.
A promising hydrous cerium oxide modified graphene (GNP-HCO) adsorbent with rapid adsorption kinetics and excellent adsorbing capacity towards arsenic removal.
It is of technical interest to develop low-cost, high-quality and scalable photosensitizers that could efficiently harvest visible light. Here we design an efficient photoelectrocatalyst by integrating a recently developed gold nanocluster (AuNC, as photosensitizer) into two types highly ordered TiO2 nanotube arrays (TNAs, substrates host the photosensitizers). The TNA electrodes used in this study are short (∼0.5 µm length, synthesized anodic oxidation aqueous hydrofluoric (HF) acid...
Peripheral nerve injury (PNI) is a common surgical disease. In recent years, with the development of tissue engineering materials, guidance conduit (NGC) expected to replace autologous transplantation and become new method for treatment PNI. this work, we developed multifunctional silk fibroin (SF)/gelatin-tyramine (GT) composite hydrogel flexible adjustable size by using diffusion-driven cross-linking method. Furthermore, ZIF-8 nanoparticles loaded miR-29a ([email protected]) delivery...
As an effective ECL emitter, tetraphenylethene (TPE)-based molecules have recently been reported with aggregation-induced electrochemiluminescence (AIECL) property, while it is still a big challenge to control its aggregation states and obtain uniform aggregates intense emission. In this study, we develop three TPE derivatives carrying pyridinium group, alkyl chain, quaternary ammonium group via the Menschutkin reaction. The resulting exhibit significantly red-shifted FL enhanced emissions...
Superresolution microscopy based on stimulated Raman scattering (SRS) is appealing for label-free quantitative imaging of biological and biomedical systems with higher resolution than conventional SRS microscopy, which diffraction-limited. This study experimentally demonstrates a saturated (SSRS) technique to break the diffraction limit vibrational samples, such as chloroplasts Hela cells. The holds great promise studying living
Here, we investigate the role of SmERF73, a group VII ETHYLENE RESPONSE FACTOR stress response transcription factor, in regulation post-modification skeleton precursors diterpene tanshinones Salvia miltiorrhiza. Most genes found to be involved tanshinone biosynthesis are located on chromosome 6, and five these comprise large gene cluster S. We that SmERF73 overexpression miltiorrhiza coordinately up-regulated seven biosynthetic genes, four which were cluster, consequently increasing...
Three novel LS(2)-type dimeric-cholesteryl derivatives (1-3), where S is a steroidal residue and L stands for linker connecting the two residues contains three benzene rings amide carbamate groups, were designed prepared. The compounds can gel wide variety of organic solvents via different ways, including mixing at room temperature, heating-cooling cycle, ultrasound treatment. SEM measurements revealed that structures concentrations gelators, nature solvent, preparation method employed have...
Low mass transfer efficiency and unavoidable matrix effects seriously limit the development of rapid accurate determination biosensing systems. Herein, we have successfully constructed an ultra-rapid nanoconfinement-enhanced fluorescence clinical detection platform based on machine learning (ML) DNA xerogel "probe", which was performed by detecting neutrophil gelatinase-associated lipocalin (NGAL, protein biomarker acute kidney injury). By regulating pore sizes xerogels, NGAL in xerogels can...
Cytochrome P450 enzymes play a crucial role as catalysts in the biosynthesis of numerous plant natural products (PNPs). Enhancing catalytic activity P450s host microorganisms is essential for efficient production PNPs through synthetic biology. In this study, we engineered
Luminol is a well-known electrochemiluminescence (ECL) fluorophore that applied in various sensing fields as an ECL reporter. Regulating the signal off/on transition of offers great opportunities for sensors' design; however, such attempts on luminol are extremely scarce it was regarded to lack promising modification sites. In this study, we developed four derivatives with at amine site and enol systematically explored possible caging strategies regulate emission. The electrochemical...
Metallic nanoparticles (NPs) coated with stimuli-responsive polymers (SRPs) exhibit tunable optical properties responding to external stimuli and show promising sensing applications. We present a new CO2-responsive polymer, poly(N-(3-amidino)-aniline) (PNAAN), gold NPs (AuNPs) synthesized by directly reducing HAuCl4 monomer N-(3-amidino)-aniline (NAAN). The amidine group of PNAAN can be protonated into hydrophilic amidinium dissolved CO2 (dCO2). This induces the swell detach from AuNP...