Interleukin (IL)-10 is an essential anti-inflammatory cytokine that plays important roles as a negative regulator of immune responses to microbial antigens. c-Maf has been suggested transcriptional factor for IL-10 production in CD4+ T cells and macrophages. However, it remains unclear whether participates expression B cells. In this study, we investigated the role regulation regulatory cells, well underlying molecular mechanism. We found was constitutively expressed resting upregulated...

Epithelioid haemangioendothelioma (EH) is a rare malignant tumor of vascular origin that usually arises in bone, liver, soft tissue, or lung. EH originating the pleura has been less frequently described. We describe an uncommon case pleural compressing myocardium 39-year-old woman. The patient was diagnosed with confirmed by surgery and immunohistochemistry. She sustained stable disease 14 months after diagnosis her symptoms improved systemic chemotherapy carboplatine etoposide. Complete...

Off-pump coronary artery bypass grafting (OPCAB) is a popular treatment for patients with ischemic heart disease, especially high-risk patients. However, whether OPCAB can lead to better clinical outcomes than on-pump (ONCAB) in enlarged ventricles remains controversial. This prospective randomized study was designed characterize comparison of early outcome and mid-term follow-up following ONCAB versus triple-vessel disease ventricles.Prospective trial treated at The First Affiliated...

The eastern segment of the Central Asian Orogenic Belt is traditionally called Xing'an Mongolia (XMOB). Ordovician intrusive rocks exposed in XMOB, from north to south, are Abaga-East Ujimqin Qi-Duobaoshan belt, Sonid Zuoqi-West Qi and Damaoqi-Baimaimiao-Tulinkai respectively. Zircon U–Pb dating geochemical data presented for East West Qi, Inner Mongolia. consist gabbro, diorite, granodiorite. LA-MC-ICP-MS zircon ages range 446 461 Ma. Geochemical suggest that gabbros diorites a tholeiitic...

Ependymal stem cells (EpSCs) are dormant in the adult spinal cord that proliferate rapidly and migrate to site of injury after (SCI).Although they can differentiate into neurons under appropriate conditions vitro, EpSCs mainly astrocytes vivo.Our previous study confirmed alternatively polarized macrophages (M2) facilitate differentiation towards neurons, but detailed mechanism remains elusive.In present study, we found M2 conditioned medium could upregulate expression Sirtuin 2 (SIRT2) vitro...

To summarize the effect of mild hypothermia on function organs in patients with multiple organ dysfunction syndrome after cardiopulmonary bypass surgery.The were randomly divided into two groups, northermia group (n=71) and (n=89). We immediately began cooling when test results showed syndrome, meanwhile all groups drawn blood to gas, liver kidney function, coagulation evaluated cardiac using echocardiography from 12 36 hours. compared difference intra-aortic balloon pump, extracorporeal...

Acetaminophen (APAP), an antipyretic and analgesic commonly used during pregnancy, has been recognized as a novel environmental contaminant. Preliminary evidence suggests that prenatal acetaminophen exposure (PAcE) could adversely affect offspring's gonadal neurologic development, but there is no systematic investigation on the characteristics of APAP's fetal developmental toxicity. Pregnant mice were treated with 100 or 400 mg/kg∙d APAP in second-trimester, second- third-trimester,...

Maternal exposure to dexamethasone can cause developmental toxicity of long bones in offspring. However, the effect on trans-differentiation growth plate chondrocytes into osteoblasts and its role bone dysplasia fetuses caused by prenatal (PDE) remains unclear. In this study, pregnant mice were treated with different doses, stages, courses according clinical practice reveal phenomenon. Further, vitro clarify phenomenon mechanism. The results showed that PDE fetal female male mice,...

ABSTRACT Introduction Regular physical activity helps improve cardiovascular and cerebrovascular skills. How to evaluate the nervous tension of vessels through sports is a hot topic. Objective The paper discusses influence regular participation in on people’s function blood-related indicators. Methods We select 30 healthy older adults who regularly participate sports, record their ECG changes, blood pressure, heart rate other related indicators, analyze elderly. Detection cell count (RBC),...

To make risk stratification of aged patients with coronary artery disease by deceleration capacity rate (DC) and heart runs (DRs) to investigate the value two detection technologies in warning sudden cardiac death.Two hundrend eighteen diagnosed (CAD) angiography (CAG) were selected as observa-tion group:including 55 latent (LCHD), 56 acute myocardial infarction (AMI), 53 angina pectoris (AP), 54 ischemic failure. Fifty-five healthy controls our hospital at same time (control group). All...

Abstract Maternal exposure to dexamethasone can cause developmental toxicity of long bones in offspring. However, the effect on trans-differentiation growth plate chondrocytes into osteoblasts and its role bone dysplasia fetuses caused by prenatal (PDE) remains unclear. In this study, pregnant mice were treated with different doses, stages, courses according clinical practice reveal phenomenon. Further, vitro clarify phenomenon mechanism. The results showed that PDE fetal female male mice,...

To determine the role of nitric oxide (NO) in intestinal motility dysfunction rats subjected to hemorrhagic shock (HS).Sixteen male Wistar were randomly and equally divided into two groups. The HS model rat was induced by bleeding from femoral artery. After animal models made, different inducers added, duodenum samples harvested for determination contractile response acetylcholine (ACh) vitro, activities inducible synthase (iNOS), contents NO tissue, morphological changes.The spontaneous...

During quantitative real-time polymerase chain reaction (RT-qPCR) data analysis, the selection of optimal housekeeping gene is necessary to ensure accuracy results. It noteworthy that genes commonly used in adult studies may not be applicable for fetus. However, stability analysis fetal kidney has been reported. This study intends screen compound rat kidney. In this study, eight based on literature reports (GAPDH, ACTB, 18S, HPRT, YWHAZ, HMBS, PPIA, and TBP) were selected as research object....