A5101578499- Geological and Geochemical Analysis
- Geochemistry and Geologic Mapping
- Ferroptosis and cancer prognosis
- Parasitic Infections and Diagnostics
- earthquake and tectonic studies
- Toxoplasma gondii Research Studies
- Bladder and Urothelial Cancer Treatments
- High-pressure geophysics and materials
- Hydrocarbon exploration and reservoir analysis
- Herpesvirus Infections and Treatments
- Land Use and Ecosystem Services
- Geochemistry and Geochronology of Asian Mineral Deposits
- Cancer Immunotherapy and Biomarkers
- Renal cell carcinoma treatment
- RNA modifications and cancer
- Cancer, Lipids, and Metabolism
- Wheat and Barley Genetics and Pathology
- Cytomegalovirus and herpesvirus research
- Alzheimer's disease research and treatments
- Plant Water Relations and Carbon Dynamics
- Geological and Geophysical Studies
- Atmospheric and Environmental Gas Dynamics
- Rabies epidemiology and control
- Monoclonal and Polyclonal Antibodies Research
- Cancer-related molecular mechanisms research
Sichuan University of Science and Engineering
2015-2025
Zhengzhou Children's Hospital
2025
Zhengzhou University
2023-2025
Sun Yat-sen University
2020-2024
Henan Agricultural University
2024
The First Affiliated Hospital, Sun Yat-sen University
2020-2024
Fujian Agriculture and Forestry University
2024
Henan Normal University
2024
Kunming University of Science and Technology
2024
Sinosteel (China)
2024
Clear cell renal carcinoma (ccRCC) is a highly invasive and metastatic subtype of kidney malignancy correlated with metabolic reprogramming for adaptation to the tumor microenvironment comprising infiltrated immune cells immunomodulatory molecules. The role in (TME) their association abnormal fatty acids metabolism ccRCC remains poorly understood. RNA-seq clinical data KIRC from Cancer Genome Atlas (TCGA) E-MTAB-1980 ArrayExpress dataset. Nivolumab group Everolimus CheckMate 025 study,...
We report results of laser ablation inductively coupled plasma-mass spectrometry-based dating, as well the analysis bulk-rock major and trace elements, Sr–Nd isotopes to address genesis tectonic settings Yanshanian granitoids in neighbouring sections Zhejiang, Jiangxi, Anhui provinces (the WZG region) within Yangtze block. Geochronological indicate that intense magmatic activity took place during Jurassic Cretaceous time region. Three episodes can be clearly distinguished by their...
Background and aims: Macrophages play a critical role in the development of liver diseases. As an NAD+-dependent histone deacetylase, SIRT1 inhibits inflammation fibrosis, but mechanisms are not fully understood. Our aim was to investigate molecular mechanism macrophages fibrosis. Methods: We employed CCl4-induced hepatic fibrosis rat models cultured murine RAW 264.7 vitro explore anti-fibrosis effect SIRT1. The content cytokines measured with ELISA. expression proteins associated NF-κB...
Toxoplasma gondii (T. gondii)Rhoptry proteins (TgROPs) are the major targets as key molecules for immunodiagnosis well immunoprophylaxis because of their initial presentation to host immune system. In this work, it was aimed evaluating protection effect TgROP21 DNA vaccine on experimental mice subjected T. challenge. The gene sequence encoding inserted into eukaryotic expression vector pVAX I, and western blotting indicate lysate BHK cells transfected with pVAX-TgROP21 specifically...
Agricultural practices significantly impact environmental sustainability, making the enhancement of Ecological Efficiency (AEE) crucial for China’s sustainable agricultural development. However, spatial-temporal evolution patterns and underlying driving forces AEE remain insufficiently understood in context rapid transformation. To address this research gap, we analyzed across 30 Chinese provinces from 2000 to 2021, identifying spatial key influencing factors. Employing a Super-Efficiency...
Trichomonas vaginalis (TV) is a protozoan parasite that causes trichomoniasis, sexually transmitted disease, worldwide. In this study, we investigated the prevalence and genetic characterization of T. contrasted most prevalent strains isolated from Xinxiang City, Henan Province, China. September 2015 to 2017, total 267 (1.64%, 95% confidence interval, CI: 1.45–1.85) clinical vaginalis-positive samples vaginal secretions were observed by wet mount microscopy 16,294 women with some symptoms...
Most localized human renal clear cell carcinoma (ccRCC)-related deaths result from cancer recurrence and metastasis. However, the precise molecular mechanisms largely remain unknown. In recent years, an increasing number of long noncoding RNAs (lncRNAs) have been shown to be vital regulators tumorigenesis. this study, we characterized a lncRNA DUXAP9 upregulation was analyzed by quantitative real-time PCR in 112 pairs ccRCC tumor tissues compared with adjacent normal tissues. Kaplan–Meier...
Abstract Background Active surveillance (AS) with delayed intervention has gained acceptance as a management strategy for small renal masses (SRMs). However, during AS, there is risk of tumor growth. Thus, we aim to investigate whether growth in patients SRMs leads progress. Methods In this study, enrolled 16,070 from the Surveillance, Epidemiology, and End Results database T1a cell carcinoma (RCC) between 2004 2017. The were divided into three groups: 10,526 partial nephrectomy (PN) group,...
As one of the 10 most common cancers in men, incidence renal cell carcinoma (RCC) has been increasing recent years. Clear (ccRCC) is pathological type RCC, counting for 80%-90% cases. Immunotherapy becoming increasingly important treatment advanced RCC. Tumor mutation burden (TMB) a potent marker predicting response to immune checkpoint blockade (ICB) treatment. Here, we analyzed somatic data ccRCC from The Cancer Genome Atlas datasets. We found that frequently mutated gene SYNE1 associated...
Abstract Tomatoes are frequently challenged by various pathogens , among which Phytophthora capsici ( P. ) is a destructive soil‐borne pathogen that seriously threatens the safe production of tomatoes. Plant growth‐promoting rhizobacteria (PGPR) positively induced plant resistance against multiple pathogens. However, little known about role and regulatory mechanism PGPR in tomato to . Here, we identified new strain Serratia plymuthica S. ), HK9‐3, has significant antibacterial effect on...
Toxocariasis is a zoonotic disease that poses threat to public health worldwide. In the present study, we investigated seroprevalence of Toxocara infection among primary school children in Henan province, central China, which was previously unknown. Sera from 2451 were collected September 2015 October 2018, and evaluated for anti- antibodies by enzyme-linked immunosorbent assay (ELISA). The overall 5.14% (126/2451). main risk factors related identified this study age children, residence area...
Triggering receptors expressed by myeloid cells-1 (TREM1) is a receptor belonging to the immunoglobulin superfamily and plays an important role in pro-inflammation acute chronic inflammatory disorders. However, understanding of immunomodulatory roles TREM1 tumor microenvironment remains incomplete.The expression patterns mRNA tumors adjacent normal tissues were compared analyzing data obtained from Genotype-Tissue Expression The Cancer Genome Atlas datasets. Survival analysis was performed...
The growth of the network data is beyond processing capacity existing IT infrastructure. At same time, "big data" also a major influence on consumer's behavior. C2C e-commerce consumption pattern experiencing vigorous development time electronic commerce in China. Because its low threshold setting up shop which occupying less money, operating costs and obvious price advantages, low-income groups are welcome to this pattern. In case, article analyzed from five aspects: consumer behavior...
Toxoplasma gondii (T. gondii) rhoptry proteins (TgROPs) have been considered main targets and indicator molecules for immune diagnosis prophylaxis since they initially present during the process of invasion. In this study, effect intramuscularly injecting genetic vaccine pVAX-ROP22 was evaluated, made by inserting TgROP22 sequence into eukaryotic expression vector pVAX I, BALB/c mice. The levels IgG, IgG1, IgG2a in vaccinated animals were integrally increased. It uncovered cytokine profile...
Rabbits ( Oryctolagus cuniculus ) are frequently reared for meat production in China. The aim of this study was to assess the seroprevalence Toxoplasma gondii and Encephalitozoon cuniculi , risk factors infection domestic rabbits raised Henan province, central 1,213 serum samples were collected tested anti- T. E. antibodies using a modified agglutination test (MAT) an enzyme-linked immunosorbent assay (ELISA), respectively. positive rates 128/1,213 (10.55%) 235/1,213 (19.37%), Co-infection...
The trace element compositions of zircons from four granitoids/metagranitoids in the Xiaoqinling area TransNorth China Orogen North Craton were determined by in-situ laser ablation (LA) ICP-MS. results used to compute zircon Ce anomaly, Ti-in-zircon temperature, and magma oxygen fugacity. Generally, anomalies with La-Pr interpolation are prone be underestimated due influence tiny inclusions or analytical errors. This underestimation can markedly data processing generate unrealistically low...
The eastern segment of the Central Asian Orogenic Belt is traditionally called Xing'an Mongolia (XMOB). Ordovician intrusive rocks exposed in XMOB, from north to south, are Abaga-East Ujimqin Qi-Duobaoshan belt, Sonid Zuoqi-West Qi and Damaoqi-Baimaimiao-Tulinkai respectively. Zircon U–Pb dating geochemical data presented for East West Qi, Inner Mongolia. consist gabbro, diorite, granodiorite. LA-MC-ICP-MS zircon ages range 446 461 Ma. Geochemical suggest that gabbros diorites a tholeiitic...