A5053488524- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Cardiovascular Effects of Exercise
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiovascular and exercise physiology
- Cardiac Valve Diseases and Treatments
- Pulmonary Hypertension Research and Treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Neuroscience and Neural Engineering
- Cardiac electrophysiology and arrhythmias
- Medical and Biological Ozone Research
- Mitochondrial Function and Pathology
- Nerve Injury and Rehabilitation
- Muscle Physiology and Disorders
- Congenital Anomalies and Fetal Surgery
- Cardiovascular Syncope and Autonomic Disorders
- Metabolism and Genetic Disorders
- Tissue Engineering and Regenerative Medicine
- Genetic Neurodegenerative Diseases
- Cardiac Structural Anomalies and Repair
- Cardiomyopathy and Myosin Studies
- Cardiovascular Conditions and Treatments
- Neurogenetic and Muscular Disorders Research
- Muscle activation and electromyography studies
Wilhelmina Children's Hospital
2007-2017
University Medical Center Utrecht
2009-2017
Boston Children's Hospital
2009-2014
Utrecht University
2009-2012
The oxygen uptake efficiency slope (OUES) has been proposed as an independent and objective alternative to the peak (VO2peak), which does not require maximal exercise. aim of this study was investigate construct group validity OUES in children with congenital heart disease (CHD). Thirty-one patients CHD, 16 (mean age ± SD 11.2 2.7 years) a Fontan repair 15 13.2 3.6 surgical tetralogy Fallot (ToF) completed symptom-limited cardiopulmonary exercise test. calculated normalized for body surface...
The management of patients with isolated congenital complete atrioventricular block (CCAVB) has changed during the last decades. current policy is to pace majority based on a variety criteria, among which limited exercise capacity. Data regarding capacity in this population stems from previous publications reporting small case series unpaced patients. Therefore, we have investigated group contemporary children CCAVB. Sixteen (mean age 11.5 ± 4; seven boys, nine girls) CCAVB were tested. In...
In Brief Purpose: To determine exercise response during cardiopulmonary testing in children and adolescents with dystrophinopathies. Methods: Exercise on the test (CPET) was compared a standard care protocol. Results: Nine boys (aged 10.8 ± 4.7 years) Becker muscular dystrophy (n = 6) Duchenne 3) were included. The feasibility of CPET similar to protocol, no serious adverse events occurred. 67% subjects normal or only mildly impaired functional capacity, could be used detect moderate severe...
Cardiopulmonary exercise testing (CPET) in pediatric patients differs many aspects from the tests as performed adults. Childrens cardiopulmonary responses during present different characteristics, particularly indices of respiratory gas exchange (e.g. oxygen uptake, ventilation and ventilatory efficiency), which are essential interpreting hemodynamic data. Diseases that associated with myocardial ischemia very rare children. Important indications for CPET children evaluation capacity...
Genetics and cardiac arrhythmias 247Group C: Patients with pathogenic mutation related to BrS in the SCN5A gene, but without type 1 ECG pattern.The endpoint of study was occurrence a first LAE during follow-up.Clinical course determined Kaplan Meier method.Results: Overall, n=131 patients (73% males; age at visit 8±0.4 years) were included followed-up for 5.4±0.4years.GROUP A comprised n=35 (77% males, 80% spontaneous pattern, 10±0.9 years): one patient presented medical attention after an...