François Lefèvre

ORCID: 0000-0003-2242-7251
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About
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Research Areas
  • Bioenergy crop production and management
  • Forest Management and Policy
  • Classical Antiquity Studies
  • Agriculture and Rural Development Research
  • Forest ecology and management
  • French Urban and Social Studies
  • Ancient Mediterranean Archaeology and History
  • Ecology and Vegetation Dynamics Studies
  • Forest Insect Ecology and Management
  • Forest Ecology and Biodiversity Studies
  • Genetic diversity and population structure
  • African Botany and Ecology Studies
  • Plant Molecular Biology Research
  • Plant and animal studies
  • Botany and Plant Ecology Studies
  • Horticultural and Viticultural Research
  • Yeasts and Rust Fungi Studies
  • Mediterranean and Iberian flora and fauna
  • Byzantine Studies and History
  • Historical, Religious, and Philosophical Studies
  • Plant and Fungal Interactions Research
  • Genetically Modified Organisms Research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Plant Water Relations and Carbon Dynamics
  • Plant Parasitism and Resistance

Écologie des Forêts Méditerranéennes
2015-2024

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2015-2024

Sorbonne Université
2022

Sorbonne Paris Cité
2022

Virologie et Immunologie Moléculaires
2006-2021

Institut National de la Recherche Agronomique
1994-2019

Académie de Paris
2017

Hôpitaux Universitaires de Strasbourg
2017

Institut National de la Recherche Agronomique du Niger
2005-2014

Soil Science Research Unit
2012

Summary Rapid climate change both imposes strong selective pressures on natural populations – potentially reducing their growth rate and causing genetic evolution affects the physiology development of individual organisms. Understanding predicting fates under global change, including extinctions geographical range shifts, requires analysing interplay these processes, which has long been a grey area in evolutionary biology. We review recent theory interaction phenotypic plasticity, demography...

10.1111/j.1365-2435.2012.02043.x article EN Functional Ecology 2012-08-24

Current strategies to prevent or treat human papillomavirus type 16 (HPV-16) infection are promising, but remain costly. More economical efficient vaccines thus needed. In this study, we evaluated the protective effects of mucosally coadministered live Lactococcus lactis strains expressing cell wall-anchored E7 Ag and a secreted form IL-12 HPV-16-induced tumors in murine model. When challenged with lethal levels tumor line TC-1 E7, immunized mice showed full prevention TC-1-induced tumors,...

10.4049/jimmunol.175.11.7297 article EN The Journal of Immunology 2005-12-01

The sustainability of agro-ecosystems depends on their ability to deliver an entire package multiple ecosystem services, rather than provisioning services alone. New social and ecological dimensions agricultural management must be explored in landscapes, foster this ability. We propose a social–ecological framework for the service-based agro-ecosystems, specified through explicit symmetric representation system, dynamic links between them. It highlights how practices, with effects, could...

10.1016/j.cosust.2015.04.001 article EN cc-by-nc-nd Current Opinion in Environmental Sustainability 2015-04-17
Tong Qiu Robert A. Andrus Marie‐Claire Aravena Acuña Davide Ascoli Yves Bergeron and 95 more Roberta Berretti Daniel Berveiller Michał Bogdziewicz Thomas Boivin Raúl Bonal Don C. Bragg Thomas Caignard Rafael Calama J. Julio Camarero Chia‐Hao Chang‐Yang Natalie L. Cleavitt Benoı̂t Courbaud François Courbet T. Curt Adrian J. Das Evangelia N. Daskalakou Hendrik Davi Nicolas Delpierre Sylvain Delzon Michael C. Dietze Sergio Donoso Calderón Laurent Dormont Josep María Espelta Timothy J. Fahey William Farfán-Ríos Catherine A. Gehring Gregory S. Gilbert Georg Gratzer Cathryn H. Greenberg Qinfeng Guo Andrew Hacket‐Pain Arndt Hampe Qingmin Han Janneke Hille Ris Lambers Kazuhiko Hoshizaki Inés Ibáñez Jill F. Johnstone Valentin Journé Daisuke Kabeya Christopher L. Kilner Thomas Kitzberger Johannes M. H. Knops Richard K. Kobe Georges Künstler Jonathan G. A. Lageard Jalene M. LaMontagne Mateusz Ledwoń François Lefèvre Theodor D. Leininger Jean‐Marc Limousin James A. Lutz Diana Macias Eliot J. B. McIntire Christopher M. Moore Emily Moran Renzo Motta Jonathan A. Myers Thomas A. Nagel Kyotaro Noguchi Jean‐Marc Ourcival Robert Parmenter Ian S. Pearse Ignacio Manuel Pérez-Ramos Łukasz Piechnik John R. Poulsen Renata Poulton‐Kamakura Miranda D. Redmond Chantal D. Reid Kyle C. Rodman Francisco Rodríguez‐Sánchez Javier Sanguinetti C. Lane Scher William H. Schlesinger Harald Schmidt Van Marle Barbara Seget Shubhi Sharma Miles R. Silman Michael A. Steele Nathan L. Stephenson Jacob N. Straub I‐Fang Sun Samantha Sutton Jennifer J. Swenson Margaret Swift Peter A. Thomas María Uriarte Giorgio Vacchiano Thomas T. Veblen Amy V. Whipple Thomas G. Whitham Andreas P. Wion Boyd R. Wright S. Joseph Wright‬ Kai Zhu Jess K. Zimmerman

Abstract The relationships that control seed production in trees are fundamental to understanding the evolution of forest species and their capacity recover from increasing losses drought, fire, harvest. A synthesis fecundity data 714 worldwide allowed us examine hypotheses central quantifying reproduction, a foundation for assessing fitness trees. Four major findings emerged. First, is not constrained by strict trade-off between size numbers. Instead, numbers vary over ten orders magnitude,...

10.1038/s41467-022-30037-9 article EN cc-by Nature Communications 2022-05-02

We have characterized a new gene, SWI1, involved in sister chromatid cohesion during both male and female meiosis Arabidopsis thaliana. A first allele, swi1.1, was obtained as T-DNA tagged mutant described previously abnormal exclusively meiosis. isolated swi1.2, which is defective for In swi1.2 meiosis, the classical steps of prophase were not observed, especially because homologs do synapse. Chromatid arms centromeres lost their stepwise manner before metaphase I, 20 chromatids instead...

10.1101/gad.203201 article EN Genes & Development 2001-07-15

Summary 1 We used genetic markers to study gene flow of the riparian pioneer tree species Populus nigra along Drôme river (France). This dioecious is supposed have more efficient dispersal mechanisms for pollen (wind) and seeds (wind water) than other trees. 2 Seedlings belonging same reproduction/migration event were sampled in 22 forest fragments their diversity assessed through six nuclear microsatellites. 3 found a high level significant differentiation among populations. The isolation...

10.1046/j.1365-2745.2003.00772.x article EN Journal of Ecology 2003-05-14

Managing forests under climate change requires adaptation. The adaptive capacity of forest tree populations is huge but not limitless. Integrating evolutionary considerations into forestry practice will enhance the managed to respond climate-driven changes. Focusing on natural regeneration systems, we propose a general framework that can be used in various and complex local situations by managers, combination with their own expertise, integrate decision making for emergence an...

10.1007/s13595-013-0272-1 article EN cc-by Annals of Forest Science 2013-03-07

Abstract Dynamic conservation of forest genetic resources (FGR) means maintaining the diversity trees within an evolutionary process and allowing generation turnover in forest. We assessed network forests areas managed for dynamic FGR (conservation units) across Europe (33 countries). On basis information available European Information System on (EUFGIS Portal), species distribution maps, environmental stratification continent, we developed ecogeographic indicators, a marginality index,...

10.1111/j.1523-1739.2012.01961.x article EN Conservation Biology 2012-12-12
Tong Qiu Marie‐Claire Aravena Acuña Davide Ascoli Yves Bergeron Michał Bogdziewicz and 90 more Thomas Boivin Raúl Bonal Thomas Caignard Maxime Cailleret Rafael Calama Sergio Donoso Calderón J. Julio Camarero Chia‐Hao Chang‐Yang Jérôme Chave Francesco Chianucci Benoı̂t Courbaud Andrea Cutini Adrian J. Das Nicolas Delpierre Sylvain Delzon Michael C. Dietze Laurent Dormont Josep María Espelta Timothy J. Fahey William Farfán-Ríos Jerry F. Franklin Catherine A. Gehring Gregory S. Gilbert Georg Gratzer Cathryn H. Greenberg Arthur Guignabert Qinfeng Guo Andrew Hacket‐Pain Arndt Hampe Qingmin Han Jan Holík Kazuhiko Hoshizaki Inés Ibáñez Jill F. Johnstone Valentin Journé Thomas Kitzberger Johannes M. H. Knops Georges Künstler Hiroko Kurokawa Jonathan G. A. Lageard Jalene M. LaMontagne François Lefèvre Theodor D. Leininger Jean‐Marc Limousin James A. Lutz Diana Macias Anders Mårell Eliot J. B. McIntire Christopher M. Moore Emily Moran Renzo Motta Jonathan A. Myers Thomas A. Nagel Shoji Naoe Mahoko Noguchi Michio Oguro Robert Parmenter Ian S. Pearse Ignacio Manuel Pérez-Ramos Łukasz Piechnik Tomasz Podgórski John R. Poulsen Miranda D. Redmond Chantal D. Reid Kyle C. Rodman Francisco Rodríguez‐Sánchez Pavel Šamonil Javier Sanguinetti C. Lane Scher Barbara Seget Shubhi Sharma Mitsue Shibata Miles R. Silman Michael A. Steele Nathan L. Stephenson Jacob N. Straub Samantha Sutton Jennifer J. Swenson Margaret Swift Peter A. Thomas María Uriarte Giorgio Vacchiano Amy V. Whipple Thomas G. Whitham Andreas P. Wion S. Joseph Wright‬ Kai Zhu Jess K. Zimmerman Magdalena Żywiec James S. Clark

10.1038/s41477-023-01446-5 article EN Nature Plants 2023-06-29

Summary. Antiviral activities present in uterine flushings from pregnant Large White, White 'hyperprolific', and prolific Meishan gilts, between Days 8 20 of gestation were compared. Flushings (20 ml) all gilts 14 positive an in-vitro interferon (IFN) assay using vesicular stomatitis virus as a challenge infection. Highest antiviral (of up to 400 000–1 200 000 total Units/flushing) obtained at Day 16 gestation, i.e. clearly after the beginning attachment. There was no major difference breeds...

10.1530/jrf.0.0910469 article EN Reproduction 1991-03-01

Low stringency screening of day 14-15 pig conceptus cDNA library using an interferon (IFN)-omega probe has led to the isolation a novel type one (type I) IFN gene physiologically expressed by trophoblast during period implantation in uterus. It encodes 170-amino acid preprotein with two potential N-glycosylation sites and predicted N-terminal signal peptide 21 residues. This protein was shorter richer Cys residues than other I IFNs distantly related all them including IFN-tau, ruminants,...

10.1016/s0021-9258(19)36579-2 article EN cc-by Journal of Biological Chemistry 1993-09-01

Abstract There is an increasing recognition that long distance dispersal (LDD) plays a key role in establishing spatial genetic structure during colonization. Recent works, focused on short dispersal, demonstrated neutral mutation arising at the colonization front can either ‘surf’ with wave and reach high frequencies or stay near its place of origin low frequencies. Here, we examine how LDD, more generally shape kernel, modifies this phenomenon width corridor affects fate mutation. We...

10.1111/j.1420-9101.2009.01832.x article EN Journal of Evolutionary Biology 2009-09-07

A transnational network of genetic conservation units for forest trees was recently documented in Europe aiming at the evolutionary processes and adaptive potential natural or man-made tree populations. In this study, we quantified vulnerability individual whole to climate change using favourability models estimated velocity change. Compared overall niche analysed target species populations warm dry end are underrepresented network. However, by 2100, 33-65 % units, mostly located southern...

10.1111/gcb.12476 article EN Global Change Biology 2013-11-24

Abstract Purpose of Review Recognizing that in the context global change, tree genetic diversity represents a crucial resource for future forest adaptation, we review and highlight major genetics research achievements past decades biodiversity-rich countries Mediterranean region. For this, conducted bibliometric analysis scientific literature spanning thirty years (1991–2020). Putting together representative regionwide expertise our co-authorship, propose perspectives next decade. Recent...

10.1007/s40725-022-00169-8 article EN cc-by Current Forestry Reports 2022-07-25

As drought-induced mortality increases globally in forest biomes, it becomes necessary for foresters to have access reliable predictors of species vulnerability drought and risk under different climatic scenarios. On the one hand, there exist several "operational" indicators resistance, which are based on observations, expert knowledge bioclimate (e.g. Ellenberg, Rameau, ClimEssences). other as traits can now be measured at high throughput, functional (such plant hydraulic traits) been...

10.1101/2025.02.06.636586 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2025-02-08
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