A5101804415- Infection Control and Ventilation
- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- COVID-19 and healthcare impacts
- Head and Neck Surgical Oncology
- Vestibular and auditory disorders
- Advanced Neuroimaging Techniques and Applications
- Hearing, Cochlea, Tinnitus, Genetics
- Childhood Cancer Survivors' Quality of Life
- Cancer survivorship and care
- Cancer-related cognitive impairment studies
- Nasal Surgery and Airway Studies
- COVID-19 epidemiological studies
- Infrared Thermography in Medicine
- Neurobiology of Language and Bilingualism
- Ophthalmology and Eye Disorders
- Fetal and Pediatric Neurological Disorders
- AI in cancer detection
- Inhalation and Respiratory Drug Delivery
- Ion channel regulation and function
- Brain Metastases and Treatment
- Genetic Neurodegenerative Diseases
- Traumatic Brain Injury Research
- Diet and metabolism studies
- Psychotherapy Techniques and Applications
Queen Elizabeth University Hospital
2018-2024
University of Edinburgh
2020-2023
Edinburgh College
2023
University of Glasgow
2018-2022
Great Ormond Street Hospital
2021
University College London
2021
University of Auckland
2010
The SARS-CoV-2 virus is primarily transmitted through virus-laden fluid particles ejected from the mouth of infected people. Face covers can mitigate risk transmission but their outward effectiveness not fully ascertained. Objective: by using a background oriented schlieren technique, we aim to investigate air flow person while quietly and heavily breathing, coughing, with different face covers. Results: found that all without an outlet valve reduce front at least 63% perhaps as high 86% if...
Respiratory droplets are the primary transmission route for SARS-CoV-2, a principle which drives social distancing guidelines. Evidence suggests that virus can be reduced by face coverings, but robust evidence how mask usage might affect safe parameters is lacking. Accordingly, we set out to quantify effects of coverings on respiratory tract droplet deposition. We tested an anatomically realistic manikin head ejected fluorescent water and human volunteers, in speaking coughing conditions...
Abstract Supplementary motor area (SMA) syndrome is characterised by transient disturbance in volitional movement and speech production which classically occurs after injury to the medial premotor area. We present two cases of SMA following isolated surgical frontal aslant tract (FAT) with intact. The first case occurred resection a left operculum tumour. second transcortical approach ventricular neurocytoma. clinical picture fMRI activation patterns during recovery were typical for support...
Abstract Purpose Posterior fossa tumour surgery in children entails a high risk for severe speech and language impairments, but few studies have investigated the effect of on prior to surgery. The current crosslinguistic study addresses this gap. We prevalence preoperative word-finding difficulties, examined associations with medical demographic characteristics, analysed lexical errors. Methods included 148 aged 5–17 years posterior tumour. Word-finding ability was assessed by means...
Abstract Respiratory droplets are the primary transmission route for SARS-CoV-2. Evidence suggests that virus can be reduced by face coverings, but robust evidence how mask usage might affect safe distancing parameters is lacking. Accordingly, we investigate effectiveness of surgical masks and single-layer cotton on mitigating dispersion large respiratory (i.e. non aerosol). We tested a manikin ejecting fluorescent human volunteers in speaking coughing conditions. quantified number flight...
Abstract Background There are no effective treatments for brain tumor-related fatigue. We studied the feasibility of two novel lifestyle coaching interventions in fatigued tumor patients. Methods This phase I/feasibility multi-center RCT recruited patients with a clinically stable primary and significant fatigue (mean Brief Fatigue Inventory [BFI] score ≥ 4/10). Participants were randomized 1–1–1 allocation ratio to: Control (usual care); Health Coaching (“HC”, an eight-week program...
Background: Brain tumours are the most common childhood tumours. Half of them in posterior fossa, where surgical removal is complicated by postoperative speech impairment (POSI) up to 25% patients. POSI manifests within days surgery, while improvement takes weeks or months. The approach midline tumours, mostly undertaken transvermian telovelar routes, has been proposed influence risk POSI. We investigated developing POSI, time course its resolution and association with other clinical...
Abstract BACKGROUND Seizures are common in brain tumours (BTs). With no fixed guidelines to guide anti-epileptics (AEDs) discontinuation BTs, we evaluated factors influencing the decision discontinue AEDs and its outcome. MATERIAL AND METHODS Retrospective study on single regional centre for neuro-oncological service from April 2018 2023. Eligible BT patients were seizure free ≥ 1 year post surgery, had histologically confirmed gliomas (WHO grade I-IV) underwent gross total resection. We...
Respiratory droplets are the primary transmission route for SARS-CoV-2, a principle which drives social distancing guidelines Evidence suggests that virus can be reduced by face coverings, but robust evidence how mask usage might affect safe parameters is lacking Accordingly, we set out to quantify effects of coverings on respiratory tract droplet deposition We tested an anatomically realistic manikin head ejected fluorescent water and human volunteers, in speaking coughing conditions...