A5100647742- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Exercise and Physiological Responses
- Adipokines, Inflammation, and Metabolic Diseases
- Muscle Physiology and Disorders
- Inflammasome and immune disorders
- Adipose Tissue and Metabolism
- Peripheral Artery Disease Management
- Endoplasmic Reticulum Stress and Disease
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Adenosine and Purinergic Signaling
- Child and Adolescent Psychosocial and Emotional Development
- Cardiovascular and exercise physiology
- Atherosclerosis and Cardiovascular Diseases
- Physical Activity and Health
- Cardiac Health and Mental Health
- Bullying, Victimization, and Aggression
- Neurological Complications and Syndromes
- Early Childhood Education and Development
- Sports injuries and prevention
- Cancer-related cognitive impairment studies
- Nitric Oxide and Endothelin Effects
- Musculoskeletal pain and rehabilitation
- Angiogenesis and VEGF in Cancer
University of Houston
2016-2025
Google (United States)
2017
University of Missouri
2012-2017
Cardiovascular Research Center
2015
Texas Tech University
2012
Children's Defense Fund
2012
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2010
University of Maryland, College Park
2006-2007
Knowledge of child rearing and development is relevant to parenting the well-being children. Using a sociodemographically heterogeneous sample 268 European American mothers 2-year-olds, we assessed state mothers' knowledge; compared knowledge in groups who varied terms parenthood social status; identified principal sources factors, supports, formal classes. On whole, demonstrated fair but less than complete basic age, education, rated helpfulness written materials each uniquely contributed...
Cross-language phonological and orthographic relationship in the biliteracy acquisition of children learning to read Korean English was investigated this study. Forty-five Korean-English bilingual were tested first-language (L1; Korean) 2nd-language (L2; English) reading skills focusing on 2 processes--phonological processing. The authors found that L1 L2 strongly correlated, explained a unique amount variance pseudoword beyond skills. However, there limited skill transfer between systems....
Objectives Inflammatory cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), are individually considered important contributors to endothelial dysfunction in obesity type 2 diabetes (T2D). However, their interactions coronary arteriole uncertain. Therefore, this study aimed determine the effects of TNF-α IL-6 on experimental T2D. Methods The studies used wild (WT), diabetic mice (db/db), db/db null for TNF (dbTNF-/dbTNF-), treated with neutralizing antibody...
The study's purpose was to investigate if physical activity initiated with the start of high-fat feeding would oppose development endothelial dysfunction, and it does, then determine some potential mechanisms. C57BL/6 female mice were randomly divided into three groups: (1) control low-fat diet (LF-SED; 15% calories from fat), (2) (HF-SED; 45% (3) HF given access a voluntary running wheel (HF-RUN). Our hypothesis that HF-RUN differ in multiple markers dysfunction HF-SED after 10 weeks...
Abstract Endoplasmic reticulum (ER) stress and uncoupling protein-2 (UCP2) activation are opposing modulators of endothelial dysfunction in atherosclerosis. Exercise reduces atherosclerosis plaques enhances function. Our aim was to understand how exercise affects ER UCP2 activation, that relates an atherosclerotic murine model. Wild type (C57BL/6, WT) apolipoprotein-E-knockout (ApoE tm1Unc , ApoE KO) mice underwent treadmill training (EX) or remained sedentary for 12 weeks. Acetylcholine...
ABSTRACT Background The cellular prion protein (PrP C ), a glycoprotein encoded by the PRNP gene, is known to modulate muscle mass and exercise capacity. However, role of PrP in maintenance regeneration skeletal during ageing remains unclear. Methods This study investigated change expression formation using C2C12 cells evaluated function Prnp wild‐type (WT) knock‐out (KO) mice at different ages (1, 9 15 months). To determine homeostasis ageing, we conducted experiments via cardiotoxin...
Weightlessness during spaceflight leads to functional changes in resistance arteries and loss of cancellous bone, which may be potentiated by radiation exposure. The purpose this study was assess the effects hindlimb unloading (HU) total-body irradiation (TBI) on vasomotor responses skeletal muscle arteries. Male C57BL/6 mice were assigned control, HU (13–16 days), TBI (1 Gy 56Fe, 600 MeV, 10 cGy/min) HU-TBI groups. Gastrocnemius feed isolated for vitro study. Endothelium-dependent...
Cerebrovascular dysfunction is a critical risk factor for the pathogenesis of Alzheimer's disease (AD). The purinergic P2Y2 receptor and endoplasmic reticulum (ER) stress are tightly associated with vascular AD. However, protective effects exercise training on receptor- ER stress-associated cerebrovascular in AD mostly unknown. Control (C57BL/6, CON) (APP/PS1dE9, AD) mice underwent treadmill (EX). 2-MeS-ATP-induced dose-dependent vasoreactivity was determined by using pressurized posterior...
This paper presents a new approach for the optimal long-range generation planning. A completely analytical production costing model and reliability measure is developed under assumption of Gaussian probabilistic distribution random load fluctuations plant outages. The investment problem formulated as an control to determine optimally annual in capacity. Hamiltonian minimization performed by using version gradient projection method.
Skeletal muscle atrophy is a debilitating complication of many chronic diseases, disuse conditions, and ageing. Genome-wide gene expression analyses have identified that elevated levels microRNAs encoded by the H19X locus are among most significant changes in skeletal muscles wide scope human cachectic conditions. We previously reported important for establishment striated fate during embryogenesis. However, role H19X-encoded regulating mass adults unknown.We created transgenic mouse strain...
We address three long-standing fundamental questions about early human development and parental caregiving within a specificity framework using data from 796 infant–mother dyads 11 societies worldwide. Adopting cross-society view opens vista on universal biological origins of, contextual influences on, infant behaviours parenting practices. asked: how do practices vary across societies? How relate to other behaviours, parent practices? Are related one another? Behaviours of firstborn...
Abstract Endoplasmic reticulum (ER) stress is closely associated with atherosclerosis, but the effects of exercise on ER stress-mediated endothelial dysfunction in atherosclerosis not yet fully understood. We assessed endothelium-dependent vasodilation isolated mesenteric arteries from wild type (WT), WT (WT-EX), ApoE knockout (ApoE KO), and KO mice KO-EX). Vasodilation to acetylcholine (ACh) was elicited presence inhibitors stress, eNOS, caspase-1, UCP-2 (Tudca, L-NAME, AC-YVARD-cmk,...
Activation of the nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome mediates release pro-inflammatory cytokine interleukin (IL)-1β and thereby plays a pivotal role in inflammatory response vascular pathology. An active lifestyle has beneficial effects on inflammation-associated dysfunction obesity. However, it remains unclear how physical activity regulates NLRP3 inflammasome-mediated Therefore, we explored protective effect...
ABSTRACT Purpose The nodlike receptor family pyrin domain containing 3 (NLRP3) inflammasome is a critical player in vascular pathology as it regulates caspase-1-mediated interleukin (IL)-1β processing. Physical activity ameliorates obesity-induced inflammation and dysfunction, but the mechanisms responsible for these positive changes are incompletely understood. Here, protective effect of physical on inflammasome-associated dysfunction obesity its putative were investigated. Methods Mice fed...
A high prevalence of metabolic syndrome (MS) and cardiovascular disease among low-income individuals has often been reported. However, there is still a lack research on the relationship between basic livelihood security (BLS) MS. This study investigated MS according to activity type, dietary habits, nutrient intake characteristics receiving BLS. Data from 14,803 men 20,299 women were analyzed assess association BLS The associations various factors separately in by logistic regression...
Accelerated skeletal muscle wasting is a shared trait among many pathologies and aging. Acupuncture has been used as therapeutic intervention to control pain; however, little known about its effects on atrophy function. The study's purpose was compare the of acupuncture, electro-acupuncture, electrical stimulation cast-induced atrophy.Forty female Sprague Dawley rats were randomly divided into groups: Control, casted (CAST), CAST+Acupuncture (CAST-A), 4) CAST+Electro-acupuncture (CAST-EA),...
Depression is a substantial global health problem, affecting >300 million people and resulting in 12.7% of all deaths. causes various physical cognitive problems, leading to 5-year 10-year decrease life expectancy compared with the general population. Physical activity known be an effective, evidence-based treatment for depression. However, generally have difficulties participating owing limitations time accessibility.To address this issue, study aimed contribute development alternative...