Weidong Zhao

ORCID: 0000-0003-2258-1590
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About
Contact & Profiles
Research Areas
  • Force Microscopy Techniques and Applications
  • Lipid Membrane Structure and Behavior
  • Ovarian cancer diagnosis and treatment
  • Neuroscience and Neural Engineering
  • Photonic Crystals and Applications
  • PARP inhibition in cancer therapy
  • Electrochemical Analysis and Applications
  • Cancer Immunotherapy and Biomarkers
  • Advanced Photocatalysis Techniques
  • Surface and Thin Film Phenomena
  • Liquid Crystal Research Advancements
  • Advanced biosensing and bioanalysis techniques
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Nanoparticle-Based Drug Delivery
  • Photonic and Optical Devices
  • Inflammasome and immune disorders
  • Cancer-related molecular mechanisms research
  • Advanced Materials Characterization Techniques
  • Cancer Genomics and Diagnostics
  • Calcium Carbonate Crystallization and Inhibition
  • Photochromic and Fluorescence Chemistry
  • Supercapacitor Materials and Fabrication
  • Advancements in Battery Materials
  • thermodynamics and calorimetric analyses
  • Nanopore and Nanochannel Transport Studies

Central Hospital of Zibo
2023-2025

Gannan Medical University
2019-2025

Anhui Provincial Hospital
2021-2025

University of Science and Technology of China
2021-2024

Shandong University
2021-2024

Chinese Academy of Sciences
2012-2024

Changchun Institute of Applied Chemistry
2012-2024

Guangxi University
2024

State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2024

Beijing Institute of Technology
2023-2024

<i>In vivo</i> induction of non-neuronal cells into neurons by transcription factors offers potential therapeutic approaches for neural regeneration. Although generation induced neuronal (iN) <i>in vitro</i> and has been reported, whether iN can be fully integrated existing circuits remains unclear. Here we show that expression achaete-scute complex homolog-like 1 (<i>Ascl1</i>) alone is sufficient to convert dorsal midbrain astrocytes mice functional vivo</i>. Specific <i>Ascl1</i> in...

10.1523/jneurosci.3975-14.2015 article EN Journal of Neuroscience 2015-06-24

Importance High-quality colonoscopy reduces the risks of colorectal cancer by increasing adenoma detection rate. Routine use an automatic quality control system (AQCS) to assist in should be considered. Objective To evaluate effect AQCS on rate among colonoscopists who were moderate- and low-level detectors during routine colonoscopy. Design, Setting, Participants This multicenter, single-blind, randomized clinical trial was conducted at 6 centers China from August 1, 2021, September 30,...

10.1001/jamanetworkopen.2024.57241 article EN cc-by-nc-nd JAMA Network Open 2025-01-30

Photonic shape memory (SM) polymers based on liquid crystalline blue phase (BP) films have been fabricated by self-assembly and subsequent photopolymerization of liquid-crystal mixtures. These freestanding BP exhibit narrow photonic band gaps high reflectivity in the visible wavelength range. Multiple blue-shift colors are achieved SM programming process at different mechanical pressures. The can be attributed to a decrease effective pitch along viewing direction caused compressed...

10.1021/acsami.9b14202 article EN ACS Applied Materials & Interfaces 2019-11-12

Abstract Purpose: In patients with platinum-sensitive relapsed (PSR) ovarian cancer, olaparib maintenance monotherapy significantly improves progression-free survival (PFS) versus placebo. However, evidence in the Asian population is lacking. This first study to evaluate efficacy and tolerability exclusively PSR cancer. Patients Methods: Considering limited placebo effect significant clinical benefit of previous trials, rapid approval China, this phase III was designed as an open-label,...

10.1158/1078-0432.ccr-21-3023 article EN cc-by-nc-nd Clinical Cancer Research 2022-02-01

Abstract Magnetic resonance imaging (MRI) contrast agents, such as Magnevist (Gd‐DTPA), are routinely used for detecting tumors at an early stage. However, the rapid clearance by kidney of Gd‐DTPA leads to short blood circulation time, which limits further improvement between tumorous and normal tissue. Inspired deformability red cells, improves their circulation, this work fabricates a novel MRI agent incorporating into deformable mesoporous organosilica nanoparticles (D‐MON). In vivo...

10.1002/adma.202211578 article EN Advanced Materials 2023-03-07

Abstract Lipid rafts are membrane microdomains enriched with cholesterol, glycosphingolipids, and proteins. Although they broadly presumed to play a pivotal role in various cellular functions, there still fierce debates about the composition, even existence of lipid rafts. Here high‐resolution time‐lapse situ atomic force microscopy is used directly confirm native erythrocyte membranes. The results indicate some important aspects rafts: most size range 100–300 nm have irregular shape;...

10.1002/smll.201102183 article EN Small 2012-02-20

The BISA with high-density hot spots as reproducible SERS substrates by combining an opal structure self-assembled monolayer AuNPs is demonstrated.

10.1039/c8nr02669f article EN Nanoscale 2018-01-01

A particle-in-hemispherical honeycomb nanoarray (PIHHN) SERS substrate with ultrahigh sensitivity and polydirectional signal stability was introduced by a multi-step bottom-up method.

10.1039/d0nr02972f article EN Nanoscale 2020-01-01

The cell membrane plays a key role in compartmentalization, nutrient transportation and signal transduction, while the pattern of protein distribution at both cytoplasmic ectoplasmic sides remains elusive. Using combination single-molecule techniques, including atomic force microscopy (AFM), single molecule spectroscopy (SMFS) stochastic optical reconstruction (STORM), to study structure nucleated membranes, we found that (1) proteins side form dense layer (4 nm) on top lipid bilayer; (2)...

10.1371/journal.pone.0091595 article EN cc-by PLoS ONE 2014-05-07

This review presents up-to-date important progress in the field of liquid crystalline blue phase (BP) materials.

10.1039/c9tc04380b article EN Journal of Materials Chemistry C 2019-01-01

Abstract The ternary compound photovoltaic semiconductor Cu 3 BiS thin film‐based photoelectrode demonstrates a quite promising potential for photoelectrochemical hydrogen evolution. presented high onset of 0.9 V RHE attracts much attention and shows that the films are good as an efficient solar water splitting photoelectrode. However, CdS buffer does not fit film: conduction band offset between reaches 0.7 eV, such (CBO) significantly increases interfacial recombination ratio is main reason...

10.1002/advs.202204029 article EN cc-by Advanced Science 2022-10-17

The GeSe-TEG integrated photoelectrode presented a remarkable and record STH efficiency of over 13.5% after brief solar-light-soaking accumulation process for solar energy storage conversion.

10.1039/d2ee03655j article EN Energy & Environmental Science 2023-01-01

Abstract A process accumulated record solar to hydrogen (STH) conversion efficiency of 8% is achieved on the Cu 2 ZnSnS 4 ‐BiVO tandem cell by synergistic coupling effect thermal and photoelectrochemical (PEC) water splitting with dynamic balance energy storage greenhouse system. This first report a high unbiased STH over for due device The acts as cell, which absorbs infrared light illumination time, while thermoelectric (TD) converts into electric power, power also recycled added onto...

10.1002/advs.202205726 article EN cc-by Advanced Science 2022-12-20
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