Based on the importance of metal-centered complexes that can interact with DNA, this research focused synthesis a new Ho(iii) complex. This complex was isolated and characterized via elemental analysis, FT-IR, fluorescence, UV-vis spectroscopy. Additional confirmation structure obtained single-crystal X-ray diffraction. DNA interaction studies were carried out circular dichroism (CD) spectroscopy, absorption viscosity measurements emission spectroscopy; it proposed metal acts as an effective...

Water contamination with antibiotics promotes environmental antibiotic resistance. Tetracycline)TC), commonly used in agriculture, pollutes water and enables bacteria to develop resistance genes. Mg-Al-layered double hydroxides/Activated carbon (Mg-Al-LDH/AC) nanocomposite effectively removes tetracycline from this study. The synthesized adsorbent was characterized using Brunauer–Emmett–Teller (BET), Fourier-transform Infrared Spectroscopy (FT-IR), Field Emission Scanning Electron Microscopy...

Based on the potential anticancer properties of lanthanide complexes, activity Sm(iii) complex containing a 2,2'-bipyridine ligand (bpy) and its interaction with FS-DNA (Fish-Salmon DNA) BSA (Bovine Serum Albumin) were examined experimentally by molecular docking in this paper. Absorption fluorescence spectroscopic methods used to define thermodynamic parameters, binding constant (K b), probable mechanism. It was concluded that Sm interacts through minor groove K b 105 M-1. Also, for at 298...

Agarose gel electrophoresis, absorption, fluorescence, viscosity, and circular dichroism (CD) have been used in exploring the interaction of terbium(III) complex, [Tb(bpy)2Cl3(OH2)] where bipy is 2,2'-bipyridine, with Fish salmon DNA. electrophoresis assay, along absorption fluorescence studies, reveal between corresponding complex FS-DNA. Also, binding constants (Kb) Stern-Volmer quenching (Ksv) Tb(III) FS-DNA were determined. The calculated thermodynamic parameters suggested that mentioned...

In this study, the interactions of a novel metal complex [Dy(bpy)2Cl3.OH2] (bpy is 2,2'-bipyridine) with fish salmon DNA (FS-DNA) and bovine serum albumin (BSA) were investigated by experimental theoretical methods. All results suggested significant binding between Dy(III) FS-DNA BSA. The constants (Kb), Stern-Volmer quenching (KSV) Dy(III)-complex BSA at various temperatures as well thermodynamic parameters using Van’t Hoff equation obtained. from absorption, ionic strength, iodide ion...

Bipyridine derivatives have shown different applications in chemistry such as electron transfer, catalysis, biological systems and artificial photosynthesis. Two cobalt(II) complexes with formula [Co(5,5′-dmbipy)2(NCS)2]1 [Co(5,5′-dmbipy)3] [Co(NCS)4]2 were prepared. The metal 1 2 characterized through FT-IR, electronic absorption, elemental analysis 1H-NMR. interaction of FS-DNA was investigated by fluorescence, UV–Vis gel electrophoresis. antibacterial properties been studied vitro against...

In the article presented herein, a deoxyribonucleic acid (DNA) biosensor is introduced for Vincristine determination in pharmaceutical preparations based on modification of screen printed electrode (SPE) with double-stranded DNA (ds-DNA), polypyrrole (PP), peony-like CuO:Tb 3+ nanostructure (P-L NS). The developed sensor indicated wide linear response to concentration ranged from 1.0 nM 400.0 μM limit detection as low .21 nM. intercalation guanine led response. optimized parameters...

In this work, the terbium(III), dysprosium(III), and ytterbium(III) complexes containing 2, 2′-bipyridine (bpy) ligand have been synthesized characterized using CHN elemental analysis, FT-IR, UV–Vis 1H-NMR techniques their binding behavior with human serum albumin (HSA) was studied by UV–Vis, fluorescence molecular docking examinations. The experimental data indicated that all three lanthanide high affinity to HSA effective quenching of via static mechanism. parameters, type interaction,...

The new complexes of Cu (II) and Ni a tridentate Schiff base ligand derived from 9,10‐phenanthrenequinone p‐toluic hydrazide have been synthesized characterized by elemental analysis, electrical conductometry, FT‐IR, Mass, NMR UV–Vis. DFT calculations were carried out at B3LYP/6‐31G*(d) level for the determination optimized structure its complexes. as‐synthesized compounds screened their antimicrobial activity. Also, binding behavior with fish salmon‐DNA (FS‐DNA) human serum albumin (HSA)...

In order to estimate the biological potential of a synthesized complex [Yb(bpy)2Cl3.OH2] where bpy is 2,2'-bipyridine, its binding behavior with fish salmon-DNA (FS-DNA) and bovine serum albumin (BSA) were studied by different kinds spectroscopy molecular modeling methods. This was selected for antibacterial antifungal activities as well DNA cleavage examined agarose gel electrophoresis. The analyses fluorescence data at four temperatures done in evaluate thermodynamic parameters interaction...

To determine the chemotherapeutic and pharmacokinetic aspects of an ytterbium complex containing 2,9-dimethyl-1,10-phenanthroline (Me2Phen), in vitro binding studies were carried out with FS-DNA/BSA by employing multiple biophysical methods a molecular modeling study. There are different techniques including absorption spectroscopy, fluorescence circular dichroism studies, viscosity experiments (only case DNA), competitive used to interaction mode between DNA/BSA ytterbium-complex. The...

The present research utilized a simplified procedure for developing novel electro-chemical DNA biosensor based on carbon paste electrode (CPE) modified with three-dimensional (3D) cubic Eu3+/Cu2O nanostructures clover-like faces (Eu3+/Cu2O CLFNs). was applied to monitor interactions between dsDNA and cytarabine the first time. Then, decreased oxidation signal of guanine following as an indicator selectively determining using differential pulse voltammetry (DPV). According findings, peak...

To learn more about the chemotherapeutic and pharmacokinetic properties of a neodymium complex containing 1,10-phenanthroline (dafone), In vitro binding was investigated with bovine serum albumin fish-salmon DNA, using variety molecular modeling research biophysical approaches. A spectroscopic techniques including fluorescence absorption were used to investigate interplay between DNA/BSA complex. The findings revealed that Nd had high affinity for BSA DNA interplays through van der Waals...

To investigate the chemotherapeutic and pharmacokinetic aspects of two lanthanide complexes (Tb(III) La(III) containing 2,2′-bipyridine ligand), in vitro binding studies were carried out with BSA by employing multiple biophysical methods molecular modeling study. There are different techniques fluorescence, absorption spectroscopy competitive experiments to determine interaction mode between these complexes. These efficiently quenched emission through a static procedure. The results showed...

Abstract The current work aimed to fabricate a new cocaine sensor of octahedral palladium‐doped cobaltite composite (Oh‐Pd 2+ : Co 3 O 4 ‐C) using simple hydrothermal protocol. As‐fabricated sensing approach was validated by various methods. Energy dispersive X‐ray analysis, diffraction and scanning electron microscopy were recruited characterize our charged modified composite. electrode could sensitively detect cocaine, with lengthy linear range (0.01 μM–900.0 μM) limit detection (1.3 nM)....

In this work, the interaction of two synthesized complexes [Tb(phen)2Cl3.OH2] and [Yb(phen)2Cl3.OH2] (phen is 1,10-phenanthroline) with bovine serum albumin (BSA) were studied by UV-Vis, fluorescence, molecular docking examinations. The experimental data indicated that these lanthanide have a high binding affinity BSA effectively quenched fluorescence via static mechanism. parameters, type interaction, value resonance energy transfer, distance between estimated from analysis measurements...

In this study, the 4,9 diazafluoren-9-one ligand and [Y(Daf)

The electro-oxidation of venlafaxine (VEN) was investigated at a carbon paste electrode, the modified electrode by NiO/graphene reduce (GR) nanocomposite. structure and morphological aspects nanocomposite were approved using FE-SEM, EDAX, FT-IR. reaction process diffusion-controlled one electrochemical oxidation involved two electrons transferring protons participating. Under optimized conditions, peak currents linearly dependent on concentration VEN in range from 1.0- 40.0 μM with limit...