- Advanced biosensing and bioanalysis techniques
- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Analytical Chemistry and Sensors
- Biosensors and Analytical Detection
- Advanced Chemical Sensor Technologies
- Advanced Biosensing Techniques and Applications
- Monoclonal and Polyclonal Antibodies Research
- RNA Interference and Gene Delivery
- MicroRNA in disease regulation
- Conducting polymers and applications
- Food Allergy and Anaphylaxis Research
- Pharmacological Effects and Assays
- Molecular Junctions and Nanostructures
- RNA modifications and cancer
- Advanced Nanomaterials in Catalysis
- Biotin and Related Studies
- Biochemical Analysis and Sensing Techniques
- Analytical Chemistry and Chromatography
- Water Quality Monitoring and Analysis
- Allergic Rhinitis and Sensitization
- Analytical chemistry methods development
- Pesticide Residue Analysis and Safety
- Identification and Quantification in Food
- Microfluidic and Capillary Electrophoresis Applications
Universidad Complutense de Madrid
2016-2025
Unidad Funcional de Investigación de Enfermedades Crónicas
2024
Instituto de Salud Carlos III
2024
Faculty (United Kingdom)
2014-2021
IMDEA Nanoscience
2012-2020
Universidad Europea
2019
Madrid Institute for Advanced Studies
2013
GTx (United States)
2010
Universitat Autònoma de Barcelona
2008
Centro de Investigaciones Biológicas Margarita Salas
2008
Novel core-shell Fe3O4@poly(dopamine) magnetic nanoparticles were prepared through an in situ self-polymerization method. The hybrid nanomaterial showed average core diameter of 11 ± 3 nm and a polymer thin film thickness 1.8 0.2 nm. employed as solid supports for the covalent immobilization horseradish peroxidase (HRP), resulting biofunctionalized to construct amperometric biosensor H2O2. enzyme high sensitivity 442.14 mA M-1 cm-2, low limit detection 182 nM, wide linear range from 6.0 ×...
Nanoparticles composed of Prussian Blue, PB, and the cyanometalate structural analogues, CuFe, FeCoFe, FeCo, are examined as inorganic clusters that mimic functions peroxidases. PB acts a superior catalyst for oxidation dopamine to aminochrome by H2O2. The H2O2 in presence is 6-fold faster than CuFe. cluster FeCo does not catalyze aminochrome. most efficient generation chemiluminescence luminol is, however, lacks any catalytic activity toward chemiluminescence. order catalyzed ≫ CuFe >...
MicroRNAs (miRs) have emerged as important clinical biomarkers with both diagnostic and prognostic value for relevant diseases, such cancer. MiRs pose unique challenges detection are currently detected by northern blotting, real-time PCR, microarray techniques. These expensive, complicated, time-consuming techniques not feasible on-site miR determination. In this study, amperometric magnetobiosensors involving RNA-binding viral protein p19 a selective biorecognition element were developed...
A perspective review of recent strategies involving the use nano/microvehicles to address key challenges associated with delivery and (bio)sensing at cellular level is presented.
We report herein the design of a smart delivery system in which cargo from capped mesoporous silica (MS) nanoparticles is controlled by an integrated enzyme-based "control unit". The consists Janus-type having opposing Au and MS faces, functionalized with pH-responsive β-cyclodextrin-based supramolecular nanovalve on surface two effectors, glucose oxidase esterase, immobilized face. nanodevice behaves as enzymatic logical OR operator selectively fueled presence D-glucose ethyl butyrate.