A5050222436- CAR-T cell therapy research
- Virus-based gene therapy research
- Ferroptosis and cancer prognosis
- CRISPR and Genetic Engineering
- Glioma Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- RNA modifications and cancer
- Misinformation and Its Impacts
- Mental Health via Writing
- Hate Speech and Cyberbullying Detection
- Herpesvirus Infections and Treatments
- Mental Health Research Topics
- Counseling, Therapy, and Family Dynamics
- Posttraumatic Stress Disorder Research
- Sleep and related disorders
- Cancer Immunotherapy and Biomarkers
- Health Literacy and Information Accessibility
Twin Cities Orthopedics
2024
University of Minnesota
2024
Minneapolis VA Health Care System
2024
Nationwide Children's Hospital
2019-2023
The Ohio State University
2023
Dartmouth College
2022
Research primarily in civilian samples supports bidirectional relations between daytime factors and trauma-related nightmare (TRN) reports. This study tested the of negative affect event-related stress with nightly occurrence characteristics TRNs a sample Veterans without posttraumatic disorder (PTSD). We studied 27 U.S. combat-exposed who completed prompts across seven days an ecological momentary assessment protocol, assessing stress. Each morning they also reported whether had TRN and, if...
Reddit is a popular social media platform that has faced scrutiny for inflammatory language against those with obesity, yet there been no comprehensive analysis of its obesity-related content.We aimed to quantify the presence 4 types content on (misinformation, facts, stigma, and positivity) identify psycholinguistic features may be enriched within each one.All sentences (N=764,179) containing "obese" or "obesity" from top-level comments (n=689,447) made non-age-restricted subreddits (ie,...
Supplementary Figure from Immune Activity and Response Differences of Oncolytic Viral Therapy in Recurrent Glioblastoma: Gene Expression Analyses a Phase IB Study
<div>AbstractPurpose:<p>Previously, clinical trials of experimental virotherapy for recurrent glioblastoma multiforme (GBM) demonstrated that inoculation with a conditionally replication–competent Δγ<sub>1</sub>34.5 oncolytic herpes simplex virus (oHSV), G207, was safe. Following the initial safety study, phase Ib trial enrolled 6 adult patients diagnosed GBM recurrence from which tumor tissue banked future studies.</p>Patients and Methods:<p>Here, we...
Supplementary Figure from Immune Activity and Response Differences of Oncolytic Viral Therapy in Recurrent Glioblastoma: Gene Expression Analyses a Phase IB Study
Supplementary Figure from Immune Activity and Response Differences of Oncolytic Viral Therapy in Recurrent Glioblastoma: Gene Expression Analyses a Phase IB Study
<div>Abstract<p>Despite some success in secondary brain metastases, targeted or immune-based therapies have shown limited efficacy against primary malignancies such as glioblastoma (GBM). Although the intratumoral heterogeneity of GBM is implicated treatment resistance, it remains unclear whether this diversity observed within metastases and to what extent cancer cell–intrinsic sculpts local immune microenvironment. Here, we profiled immunogenomic state 93 spatially distinct...
Cancer treatment strategies targeting the tumor microenvironment and corresponding immune cell infiltrate (i.e., immunotherapy) have recently proven effective against many solid tumors. In pediatric brain cancers, there is little known about microenvironment. We aim to characterize populations of tumors, which will better inform us infiltration in different cancer subtypes may indicate potential for patient response immunotherapy. The Institute Genomic Medicine at Nationwide Children's...
<sec> <title>BACKGROUND</title> Reddit is a popular social media platform that has faced scrutiny for inflammatory language against those with obesity, yet there been no comprehensive analysis of its obesity-related content. </sec> <title>OBJECTIVE</title> To quantify the presence four types content on (misinformation, stigma, positivity, and facts) identify psycholinguistic features may be enriched within each one. <title>METHODS</title> All sentences (n = 764,179) containing “obese” or...