A5100664651- Meat and Animal Product Quality
- Phytochemicals and Antioxidant Activities
- Gout, Hyperuricemia, Uric Acid
- Protein Hydrolysis and Bioactive Peptides
- Polyamine Metabolism and Applications
- Aquaculture disease management and microbiota
- Proteins in Food Systems
- Chromatography in Natural Products
- Collagen: Extraction and Characterization
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Biochemical Analysis and Sensing Techniques
- Biochemical effects in animals
- Gold and Silver Nanoparticles Synthesis and Applications
- Natural product bioactivities and synthesis
- Fermentation and Sensory Analysis
- Nanocomposite Films for Food Packaging
- Gastric Cancer Management and Outcomes
- Aquaculture Nutrition and Growth
- Iron Metabolism and Disorders
- Microbial Community Ecology and Physiology
- Pancreatitis Pathology and Treatment
- Polysaccharides Composition and Applications
- Pancreatic and Hepatic Oncology Research
- PI3K/AKT/mTOR signaling in cancer
Second Affiliated Hospital of Fujian Medical University
2025
Fujian Medical University
2025
Ningbo University
2014-2025
Zhejiang Chinese Medical University
2022-2024
Key Laboratory of Guangdong Province
2024
Baotou Medical College
2023
Zhengzhou University
2018-2021
Committee on Publication Ethics
2019
Creative Commons
2019
National Natural Science Foundation of China
2019
The gelling and structural properties of microbial transglutaminase (MTGase) pectin modified fish gelatin were compared to investigate their performances on altering properties. Our results showed that within a certain concentration, both MTGase had positive effects the gelation point, melting gel strength, textural, swelling gelatin. Particularly, low content (0.5%, w/v) could give gels highest values temperature, hardness. Meantime, flow behavior increase viscosity without changing its...
Hyperuricemia is linked to a variety of disorders that can have serious consequences for human health. Peptides inhibit xanthine oxidase (XO) are expected be safe and effective functional ingredient the treatment or relief hyperuricemia. The goal this study was discover whether papain small yellow croaker hydrolysates (SYCHs) potent inhibitory (XOI) activity. results showed compared XOI activity SYCHs (IC50 = 33.40 ± 0.26 mg/mL), peptides with molecular weight (MW) less than 3 kDa (UF-3)...
Hyperuricemia arises from imbalanced uric acid metabolism, contributing to gout and related chronic diseases. When traditional drugs are used treat hyperuricemia, side effects inevitable, which promotes the exploration of new bioactive compounds. Protein hydrolysates peptides gradually showing potential in treatment hyperuricemia. This study investigated inhibitory activity extracted Trachurus japonicus using silico vitro methods. We employed virtual enzymolysis experimental validation...
Background MicroRNAs (miRNAs) represent a class of noncoding small RNAs and are implicated in many diseases. However, the role miRNA obstructive sleep apnea (OSA)-induced white adipose tissue (WAT) dysfunction remains to be fully elucidated. Using sequencing (miRNA-seq), we uncovered expression profiles chronic intermittent hypoxia (CIH)-induced WAT mice. Methods We established an apolipoprotein-deficient (ApoE−/−) CIH mouse model identified differentially expressed miRNAs (DEmiRs) using...
ABSTRACT The effects of six cooking styles, including boiling, steaming, microwaving, grilling, pan-frying and deep-frying, on the lipid oxidation fatty acid composition grass carp (Ctenopharyngodon idellus) fillets were investigated. All treatments reduced moisture contents increased relative ratio protein. Compared with raw samples, proportions polar fractions all samples increased, while free amino significantly decreased. Peroxide values decreased during but remained constant in...
Extractable and unextractable proanthocyanidins (EPAs UEPAs) from leaves of bayberry were characterized. Both EPAs UEPAs analyzed by acid catalysis in the presence excess phloroglucinol. The main cleavage product, epigallocatechin-3-O-gallate-(4β→2)-phloroglucinol, was successfully identified. prodelphinidin type. In fact, epigallocatechin-3-O-gallate (EGCG) traces epigallocatechin (EGC) detected as extension units, but only EGCG present terminal units. All compounds exhibited a 2,3-cis...
Background: Morin, one of the most widely distributed flavonoids in plants, has been identified as a potent antihyperuricemic agent. Its poor water solubility and fast vivo clearance, however, have limited its application treatment hyperuricemia. In this study, novel amphiphilic polymer (hydroxyethyl starch-deoxycholic acid [HES-DOCA]) was synthesized to overcome these limitations. Methods: HES-DOCA conjugates with various substitution degrees were prepared by chemical grafting DOCA HES...
High-fat (HF) diets and low-grade chronic inflammation contribute to the development of insulin resistance type 2 diabetes (T2D), whereas n-3 polyunsaturated fatty acids (PUFAs), due their anti-inflammatory effects, protect against resistance. Interleukin (IL)-1β is implicated in resistance, yet how PUFAs modulate IL-1β secretion attenuate HF diet-induced remains elusive. In this study, a diet activated NLRP3 inflammasome via inducing reactive oxygen species (ROS) generation promoted...
Summary This study was carried out to investigate the changes in ten biogenic amines and chemical properties stinky tofu brine during conventional production. Results show that free amino acid nitrogen positively correlated with fermentation time except primary (0–24 h) tofu. Of analysed, putrescine, cadaverine, spermidine, spermine agmatine were detected tofu, cadaverine spermidine brine, only putrescine exhibited a significant positive correlation ( P < 0.05) both sample types extended...
Abstract Objectives This study aimed to compare the biodistribution and hypouricemic efficacy of morin morin-phospholipid complex loaded self-nanoemulsifying drug delivery systems (MPC-SNEDDS), as well explore their therapeutic mechanisms. Methods We studied MPC-SNEDDS after they were orally administered rats. The mechanisms evaluated using potassium oxonate-induced hyperuricemic model in Key findings With enhanced concentration liver kidney, oral exhibited significantly stronger...