A5100382096- Advanced Polymer Synthesis and Characterization
- Catalytic C–H Functionalization Methods
- Radical Photochemical Reactions
- Carbohydrate Chemistry and Synthesis
- Chemical Synthesis and Reactions
- Innovative Microfluidic and Catalytic Techniques Innovation
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Synthetic Organic Chemistry Methods
- Fluorine in Organic Chemistry
- Machine Learning in Materials Science
- Polymer Surface Interaction Studies
- Radioactive element chemistry and processing
- Click Chemistry and Applications
- Synthesis and Catalytic Reactions
- Photopolymerization techniques and applications
- Organoboron and organosilicon chemistry
- Glycosylation and Glycoproteins Research
- Medicinal Plant Pharmacodynamics Research
- Inorganic and Organometallic Chemistry
- Proteoglycans and glycosaminoglycans research
- Luminescence and Fluorescent Materials
- Catalytic Cross-Coupling Reactions
- Asymmetric Hydrogenation and Catalysis
- Cyclopropane Reaction Mechanisms
Wuhan University of Technology
2025
University of Chicago
2023-2024
Huazhong University of Science and Technology
2024
Nankai University
2009-2023
Soochow University
2020-2023
State Key Laboratory of Silkworm Genomic Biology
2023
Southwest University
2023
Third People's Hospital of Hangzhou
2022
Tianjin University of Commerce
2022
Tianjin University
2022
A simple and robust method for electrochemical alkyl C–H fluorination is presented. Using a nitrate additive, widely available fluorine source (Selectfluor), carbon-based electrodes, wide variety of activated unactivated bonds are converted into their C–F congeners. The scalability the reaction also demonstrated with 100 gram preparation fluorovaline.
Polymerization-induced self-assembly (PISA) has been established as a powerful strategy for fabrication of polymeric nano-objects in the past decade. However, comparison with traditional method, PISA is unsatisfactory preparation vesicles chemical versatility membrane-forming block tunable membrane properties, which limits further application PISA-based vesicles. Besides stimuli-responsive property, structural integrity another important concern material applications. In situ cross-linking...
Abstract We report the development of photoredox‐catalyzed and copper‐promoted trifluoromethoxylation arenediazonium tetrafluoroborates, with trifluoromethyl arylsulfonate (TFMS) as reagent. This new method takes advantage visible‐light photoredox catalysis to generate aryl radical under mild conditions, combined selective trifluoromethoxylation. The reaction is scalable, tolerates a wide range functional groups, proceeds regioselectively conditions. Furthermore, mechanistic studies...
Significance The combination of two newly emerging methods for chemical synthesis enables access to molecular space that was previously challenging or impossible access. Thus, a C–H activation ubiquitous carboxylic acids followed by their decarboxylative functionalization provides modular difunctionalized carbon frameworks with distinctly controlled stereochemistry. Application this strategy simplify the medicinally important entities and discover potent antimalarial compounds is described.
Polybutylene succinate (PBS) is a biodegradable aliphatic polyester with excellent thermal stability, mechanical properties, and processability. The synthesis of PBS typically employs titanium-based catalysts like tetrabutyl titanate (TBT) to accelerate the reaction. However, TBT acts as homogeneous catalyst non-recyclable. This study aims minimize cost recovering liquid during by using TBT-loaded activated carbon for direct esterification optimizing process conditions. was analyzed...
Abstract Polymerization‐induced self‐assembly has been demonstrated to be a powerful strategy for fabricating polymeric nanoparticles in the last two decades. However, stringent requirements monomers greatly limit chemical versatility of PISA‐based functional and expanding monomer family PISA is still highly desirable. Herein, camptothecin analogue (CPTM) first used as PISA. Prodrug with reduction‐responsive release behavior are fabricated at 10% solid concentration (100 mg g −1 )....
A near-infrared (NIR) light induced controlled cationic polymerization is presented here. The halide abstraction reaction between the cyclopentadienyl iron dicarbonyl dimer (Fe2(Cp)2(CO)4) and an organic utilized to generate initial radicals or cations under mild conditions, which can be further combined with both radical reversible addition-fragmentation chain transfer (RAFT) polymerization. Well-defined poly(vinyl ether)s polyacrylates are prepared successfully NIR by this method....
Abstract Polymer molecular weight distribution (MWD) is a key parameter of polymers. Here we present robust method for controlling polymer MWD in controlled cationic polymerizations. A latent mediator strategy was designed and combined with temporal programming to regenerate mediators at different times during polymerization. Both the breadths shapes curves were tuned easily by adjusting an external light source. Bimodal, trimodal, tetramodal distributions obtained, could be varied from 1.06...
Abstract As the prevalence of diabetes continues to increase, number individuals living with complications will reach an unprecedented magnitude. Continuous use some synthetic agents reduce blood glucose levels causes severe side effects, and thus, demand for nontoxic, affordable drugs persists. Naturally occurring compounds, such as iminosugars derived from mulberry (Morus spp.), have been shown levels. In mulberry, 1-deoxynojirimycin (DNJ) is predominant iminosugar. However, mechanism...
Abstract Two photoluminescent coordination polymers, {[Cu 10 (μ 3 ‐Mtta) 4 7 ] · 2H 2 O} n ( 1 ), containing 2‐D wavy motifs with inorganic buckybowl analogues, and [Cu 5 (NH ) , Mtta = 5‐methyl tetrazolate), were obtained by the control of solvents auxiliary complexing agent. The ligand is a likely candidate for construction metal‐organic, fullerene‐like molecules. luminescent properties are discussed. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
The polymer molecular weight distribution (MWD) has a vital impact on material properties. Here, we presented convenient approach for controlling the MWD in batch polymerization by latent initiator strategy, which is realized photocontrolled transformation from to during polymerization. A photoinduced atom transfer radical addition reaction and living cationic were combined this method, was further utilized transform mechanism In addition, strategy also demonstrated be able initiate abundant...
Despite the growing importance of fluorinated organic compounds in pharmaceuticals, agrochemicals, and materials science, introduction fluorine into molecules is still a challenge, no catalytic fluorocarbonylation aryl/alkyl boron has been reported to date. Herein, we present development palladium phosphine synergistic redox catalysis potassium trifluoroborate. Trifluoromethyl arylsulfonate (TFMS), which was used as trifluoromethoxylation reagent, an easily handled bench-scale employed...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of Uridine 5′-diphosphoiduronic Acid: A Potential Substrate for the Chemoenzymatic Synthesis HeparinMichel Weïwer†, Trevor Sherwood†, Dixy E. Green‡, Miao Chen§, Paul L. DeAngelis‡, Jian Liu§, and Robert J. Linhardt*†∥View Author Information Department Chemistry Chemical Biology, Biological Engineering, Rensselaer Polytechnic Institute, 110 Eighth Street, Troy, New York 12180, Biochemistry Molecular University Oklahoma Health Sciences...
The composition and structure of polymers have great influence on their performances.
Comprehensive Summary Polymer dispersity ( Đ ) or molecular weight distribution (MWD) is a basic but vital parameter for the properties of polymeric materials. Developing new methodologies controlling polymer MWD emerging as research hotspot. However, methods to tune in cationic polymerization are still not well explored. Herein, we present simple method control poly(isobutyl vinyl ether) (PIBVE) by mixing two different chain transfer agents batch visible light induced RAFT polymerization. A...
Abstract We report the development of photoredox‐catalyzed and copper‐promoted trifluoromethoxylation arenediazonium tetrafluoroborates, with trifluoromethyl arylsulfonate (TFMS) as reagent. This new method takes advantage visible‐light photoredox catalysis to generate aryl radical under mild conditions, combined selective trifluoromethoxylation. The reaction is scalable, tolerates a wide range functional groups, proceeds regioselectively conditions. Furthermore, mechanistic studies...