Bi Ma

ORCID: 0000-0002-3596-8949
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About
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Research Areas
  • Chromosomal and Genetic Variations
  • Plant Virus Research Studies
  • Plant Molecular Biology Research
  • Plant Disease Resistance and Genetics
  • Plant Gene Expression Analysis
  • Genomics and Phylogenetic Studies
  • Plant-Microbe Interactions and Immunity
  • Plant biochemistry and biosynthesis
  • Silkworms and Sericulture Research
  • Plant Reproductive Biology
  • Studies on Chitinases and Chitosanases
  • Plant Stress Responses and Tolerance
  • Insect-Plant Interactions and Control
  • Plant Pathogens and Fungal Diseases
  • Silk-based biomaterials and applications
  • Higher Education and Teaching Methods
  • Industrial Technology and Control Systems
  • Environmental and Agricultural Sciences
  • Legume Nitrogen Fixing Symbiosis
  • Plant and Fungal Interactions Research
  • Plant pathogens and resistance mechanisms
  • Japanese History and Culture
  • Bioactive natural compounds
  • English Language Learning and Teaching
  • Ginseng Biological Effects and Applications

Southwest University
2015-2024

Sichuan Academy of Agricultural Sciences
2024

Sericultural Research Institute
2024

RMIT University
2024

State Key Laboratory of Silkworm Genomic Biology
2014-2023

Jiangsu University of Science and Technology
2015

Xinjiang Industry Technical College
2015

Institute of Technology of Cambodia
2015

Chongqing University
2015

China Academy of Engineering Physics
2014

Human utilization of the mulberry–silkworm interaction started at least 5,000 years ago and greatly influenced world history through Silk Road. Complementing silkworm genome sequence, here we describe a mulberry species Morus notabilis. In 330-Mb assembly, identify 128 Mb repetitive sequences 29,338 genes, 60.8% which are supported by transcriptome sequencing. Mulberry gene appear to evolve ~3 times faster than other Rosales, perhaps facilitating species' spread worldwide. The tree is among...

10.1038/ncomms3445 article EN cc-by-nc-sa Nature Communications 2013-09-19

Flavonoids are widely distributed in mulberry leaves and have been recognized for their beneficial physiological effects on the human health. Here, we analyzed variations 44 flavonoid compounds among 91 resources. Metabolic profiling revealed that O-rhamnosylated flavonols malonylated flavonol glycosides, including rutin quercetin 3-O-(6″-O-malonylglucoside) (Q3MG), were absent from Morus notabilis multiple (Morus alba L.) Transcriptome phylogenetic analyses of flavonoid-related...

10.1021/acs.jafc.9b06931 article EN Journal of Agricultural and Food Chemistry 2020-01-09

Abstract Mulberry is a fundamental component of the global sericulture industry, and its positive impact on our health environment cannot be overstated. However, mulberry reference genomes reported previously remained unassembled or unplaced sequences. Here, we report assembly analysis telomere-to-telomere gap-free genome species, Morus notabilis, which has emerged as an important in gene function research genetic improvement. The produced here provides unprecedented opportunity for us to...

10.1093/hr/uhad111 article EN cc-by Horticulture Research 2023-05-31

Cytochrome P450s play critical roles in the biosynthesis of physiologically important compounds plants. These often act as defense toxins to prevent herbivory. In present study, a total 174 P450 genes mulberry (Morus notabilis C.K.Schn) were identified based on bioinformatics analyses. divided into nine clans and 47 families found be expressed tissue-preferential manner. compared Arabidopsis thaliana. Families CYP80, CYP92, CYP728, CYP733, CYP736, CYP749 exist mulberry, they may secondary...

10.1111/jipb.12141 article EN Journal of Integrative Plant Biology 2013-12-04

Mulberry (Morus spp.) is an economically important plant as the main food used for rearing domesticated silkworm and it has multiple uses in traditional Chinese medicine. Two basic chromosome numbers notabilis, n = 7, Morus alba, 14) have been reported genus Morus, but evolutionary history relationship between them remain unclear. In present study, a 335-Mb high-quality chromosome-scale genome was assembled wild mulberry species M. notabilis. Comparative genomic analyses indicated high...

10.1093/hr/uhab030 article EN cc-by Horticulture Research 2022-01-01

miRNAs are a class of non-coding endogenous small RNAs. They play vital roles in plant growth, development, and response to biotic abiotic stress by negatively regulating genes. Mulberry trees economically important species with multiple uses. However, date, little is known about mulberry their target In the present study, three RNA libraries were constructed sequenced using high-throughput sequencing technology. Results showed 85 conserved belonging 31 miRNA families 262 novel at 371 loci....

10.1371/journal.pone.0104409 article EN cc-by PLoS ONE 2014-08-13

Proanthocyanidins (PAs) are major defense-related phenolics in mulberry, but the mechanism underlying their biosynthesis remains uncharacterized. In this study, relationship between expression of genes encoding anthocyanidin reductase (ANR) or leucoanthocyanidin (LAR) and PA was investigated white red mulberry fruits. ripening fruits, MnANR MnLAR transcription levels tended to decrease, whereas catechin epicatechin contents initially increased then decreased. contrast, content exhibited a...

10.1016/j.plantsci.2020.110473 article EN cc-by-nc-nd Plant Science 2020-03-19

Abstract DNA ‐based molecular markers play a significant role in gene mapping, genetic diversity analysis, germplasm evaluation and marker‐assisted selection. A combination of desirable marker characteristics such as abundant polymorphism, good stability, ease production high efficiency is difficult to achieve when utilizing traditional systems. Micro RNA s are type endogenous non‐coding prevalent the genomes many organisms. The conservation mi pre‐mi sequences provides an opportunity...

10.1111/pbr.12069 article EN Plant Breeding 2013-04-28

Abstract DNA methylation has been proposed to regulate plant stress resistance. However, the dynamic changes in woody plants and their correlations with pathogenic responses are not fully understood. Here, we present single-base maps of methylomes mulberry ( Morus notabilis ) leaves that were subjected a mock treatment or inoculation Botrytis cinerea . Compared former, latter showed decreased mCG mCHG levels increased mCHH levels. inhibitors reduced resistance gene enhanced resistance,...

10.1038/s41438-021-00588-x article EN cc-by Horticulture Research 2021-07-01

Abstract As the prevalence of diabetes continues to increase, number individuals living with complications will reach an unprecedented magnitude. Continuous use some synthetic agents reduce blood glucose levels causes severe side effects, and thus, demand for nontoxic, affordable drugs persists. Naturally occurring compounds, such as iminosugars derived from mulberry (Morus spp.), have been shown levels. In mulberry, 1-deoxynojirimycin (DNJ) is predominant iminosugar. However, mechanism...

10.1093/plphys/kiad065 article EN PLANT PHYSIOLOGY 2023-02-04

Mulberry has been used as an economically important food crop for the domesticated silkworm thousands of years, resulting in one oldest and well-known plant-herbivore interactions. The genome Morus notabilis now sequenced there is opportunity to mine transposable element (TE) data. To better understand roles TEs structural, functional evolutionary dynamics mulberry genome, a specific, comprehensive user-friendly web-based database, MnTEdb, was constructed. It built based on detailed accurate...

10.1093/database/bav004 article EN cc-by Database 2015-01-01

Type III polyketide synthases are important for the biosynthesis of flavonoids and various plant polyphenols. Mulberry plants have abundant polyphenols, but very little is known about mulberry type synthase genes. An analysis these genes may provide new targets genetic improvement to increase relevant secondary metabolites enhance tolerance biotic abiotic stresses. Eighteen encoding were identified, including six chalcone (CHS), ten stilbene (STS), two (PKS). Functional characterization four...

10.1186/s12864-016-2843-7 article EN cc-by BMC Genomics 2016-08-04

Miniature inverted-repeat transposable elements (MITEs) are common in eukaryotic genomes, and important for genomic evolution. In the present study, identification of MITEs mulberry genome revealed 286,122 MITE-related sequences, including 90,789 full-length elements. The amplification influence on evolution were analyzed. timing MITE amplifications varied considerably among various families. Fifty-one families have undergone a single round amplification, while other developed from multiple...

10.1186/s13100-019-0169-0 article EN cc-by Mobile DNA 2019-06-25

Abstract Mulberry is an important economic crop plant and traditional medicine. It contains a huge array of bioactive metabolites such as flavonoids, amino acids, alkaloids vitamins. Consequently, mulberry has received increasing attention in recent years. MMHub (version 1.0) the first open public repository mass spectra small chemical compounds (<1000 Da) leaves. The database 936 electrospray ionization tandem spectrometry (ESI-MS2) data lists specific distribution 91 resources with...

10.1093/database/baaa011 article EN cc-by Database 2020-01-01

Genes from the plant specific Lateral Organ Boundaries Domain (LBD) family encode transcriptional regulators that have a variety of functions in various physiological and developmental processes. In present study, 31 LBD genes were identified mulberry genome. The genome features all MnLBD phylogenetic studies with Arabidopsis protein sequences, accompanied by expression analysis each Morus provide insights into functional prediction LBDs. genome-wide surveys current resulted identification...

10.1016/j.mgene.2014.04.004 article EN cc-by-nc-nd Meta Gene 2016-03-02

The vegetative phase transition is a prerequisite for flowering in angiosperm plants. Mulberry miR156 has been confirmed to be crucial factor the Arabidopsis thaliana. over-expression of transgenic Populus × canadensis dramatically prolongs juvenile phase. Here, we find that expression mno-miR156 decreases with age all tissues mulberry, which led us study hierarchical action mulberry. Utilizing degradome sequencing and dual-luciferase reporter assays, nine MnSPLs were shown directly...

10.3390/ijms22115550 article EN International Journal of Molecular Sciences 2021-05-24

Scleromitrula shiraiana is a necrotrophic fungus with narrow host range, and one of the main causal pathogens mulberry sclerotial disease. However, its molecular mechanisms pathogenesis are unclear. Here, we report 39.0 Mb high-quality genome sequence for S. strain SX-001. The contains 11,327 protein-coding genes. number genes size similar to most other Ascomycetes. cross-similarities differences closely related Sclerotinia sclerotiorum Botrytis cinerea indicated that differentiated earlier...

10.3389/fmicb.2020.603927 article EN cc-by Frontiers in Microbiology 2021-01-14

Abstract The silkworm Bombyx mori is a domesticated insect that serves as an animal model for research and agriculture. super-pan-genome dataset, which we published last year, unique resource the study of global genomic diversity phenotype-genotype association. Here present SilkMeta (http://silkmeta.org.cn), comprehensive database covering available pan-genome multi-omics data. contains 1082 short-read genomes, 546 long-read assembled 1168 transcriptomes, 294 phenotype characterizations...

10.1093/nar/gkad956 article EN cc-by-nc Nucleic Acids Research 2023-11-06

Abstract Although many studies have shown that transposable element ( TE ) activation is induced by hybridisation and polyploidisation in plants, much less known on how different types of respond to hybridisation, the impact ‐associated sequences gene function. We investigated frequency regularity putative transposon for , determined sequence variation genome during allopolyploidisation. designed primers adopted I nter‐ R etrotransposon A mplified P olymorphism IRAP method detect process...

10.1111/plb.12121 article EN Plant Biology 2013-10-31

Mulberry (Morus spp.), in family Moraceae, is a plant with important economic value. Many polyploid levels of mulberry have been determined. In the present study, fluorescence situ hybridization (FISH) technique was applied Morus notabilis, using four single-copy sequences, telomere repeats, and 5S 25S rDNAs as probes. All mitotic chromosomes were clearly identified grouped into seven pairs homologous chromosomes. Three dot chromosome distinguished by FISH patterns rDNA probe simple sequence...

10.1038/s41598-017-10079-6 article EN cc-by Scientific Reports 2017-08-21

SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) genes, as unique plant transcription factors, play important roles in developmental regulation and stress response adaptation. Although mulberry is a commercially valuable tree species, there have been few systematic studies on SPL genes. In this work, we identified 15 full-length genes the genome, which were distributed 4 Morus notabilis chromosomes. Phylogenetic analysis clustered from five plants (Malus × domestica Borkh, Populus trichocarpa,...

10.3390/ijms23031141 article EN International Journal of Molecular Sciences 2022-01-20

The evolutionary dynamics of long terminal repeat (LTR) retrotransposons in tree genomes has remained largely unknown. availability the complete genome sequences mulberry (Morus notabilis) offered an unprecedented opportunity for us to characterize these retrotransposon elements. We investigated 202 and 114 families Copia Gypsy superfamilies, respectively, comprising 2916 intact elements genome. tRNAMet was most frequently used type tRNA both superfamilies. Phylogenetic analysis suggested...

10.3390/genes10040285 article EN Genes 2019-04-09

Abstract The acquisition of new metabolic activities is a major force driving evolution. We explored, from the perspectives gene family expansion and evolutionary adaptability proteins, how functions have arisen in which terpene synthases diverged. Monoterpenoids are diverse natural compounds that can be divided into cyclic acyclic skeleton forms according to their chemical structure. demonstrate, through phylogenetic reconstructions genome synteny analyses, (E)-β-ocimene synthases,...

10.1093/jxb/eraa353 article EN Journal of Experimental Botany 2020-07-23
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