Peter Labib
A5054515294- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Genomics and Diagnostics
- Gastric Cancer Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Genetic factors in colorectal cancer
- Colorectal Cancer Screening and Detection
- Cancer Research and Treatments
- COVID-19 and healthcare impacts
- Pediatric Hepatobiliary Diseases and Treatments
- Nanoplatforms for cancer theranostics
- Esophageal and GI Pathology
- Oral and gingival health research
- Colorectal Cancer Surgical Treatments
- Appendicitis Diagnosis and Management
- Diverticular Disease and Complications
- Climate Change and Health Impacts
- Trauma and Emergency Care Studies
- Neuroendocrine Tumor Research Advances
- Multiple and Secondary Primary Cancers
- Diet and metabolism studies
- Metastasis and carcinoma case studies
University Hospitals Plymouth NHS Trust
2019-2024
University Hospitals Birmingham NHS Foundation Trust
2024
University of Birmingham
2009-2024
Queen Elizabeth Hospital Birmingham
2024
University of Plymouth
2023
The Royal Free Hospital
2017-2022
University College London
2017-2022
Derriford Hospital
2016-2022
Roland Hill (United Kingdom)
2020
Torbay Hospital
2015-2016
Summary Surgery is a carbon‐heavy activity and creates high volume of waste. Surgical teams around the world want to deliver more environmentally sustainable surgery but are unsure what do how create change. There many interventions available, resources time limited. Capital investment into healthcare engagement senior management challenging. However, frontline can change behaviours drive wider Patients have voice here too, as they would like ensure their does not harm local community...
Background: Pancreatoduodenectomy with venous resection (PDVR) may be performed to achieve tumour clearance in patients a pancreatic ductal adenocarcinoma (PDAC) involvement. This study aimed evaluate the impact of PDVR on PDAC outcomes. Methods: In total, 435 either R0 status (n = 322) or R1 within superior mesenteric vein groove 113) were extracted from Recurrence After Whipple’s (RAW) dataset. matched 1:2 ratio standard PD patients. Comparisons then made between two groups (surgical...
Cholangiocarcinoma is a rare and aggressive malignancy of the biliary tract. Complete surgical resection can be curative, but majority patients are diagnosed with advanced disease usually die within year diagnosis. Most deaths attributable to local progression rather than distant metastases, supporting use locoregional therapies. There evidence that therapies provide tumor control resulting in increased survival while avoiding some side effects systemic treatments, increasing potential...
Differentiating hepatic mucinous cystic neoplasms (MCNs) from simple cysts (SCs) preoperatively is a challenging task. Our aim was to determine whether radiological features on ultrasound scan (USS), CT or MRI, cyst fluid tumour markers, multidisciplinary team (MDT) outcomes could differentiate MCN SC.A retrospective review of features, marker levels and MDT in 52 patients performed.There were 13 with MCN, 38 SC one ciliated foregut cyst. MCNs more often solitary (p = 0.006). Although no...
Abstract Background Pancreatoduodenectomy (PD) is associated with significant postoperative morbidity. Surgeons should have a sound understanding of the potential complications for consenting and benchmarking purposes. Furthermore, preoperative identification high-risk patients can guide patient selection potentially allow targeted prehabilitation and/or individualized treatment regimens. Using large multicentre cohort, this study aimed to calculate incidence all PD identify risk factors....
Abstract Aim Young colorectal cancer (CRC) patients are reported to have more aggressive disease, an advanced stage at diagnosis and conflicting survival outcomes. The aim of this study was analyse the demographics, clinicopathological features prognosis young CRC a population‐based level in England. Method This is retrospective review all using data from Public Health England collated regional registries between 2010 2014. Those aged 40 years below were classified as those over older....
5-Aminolevulinic acid (ALA) is a potential contrast agent for fluorescence-guided surgery in pancreatic ductal adenocarcinoma (PDAC). However, factors influencing ALA uptake PDAC have not been adequately assessed. We investigated ALA-induced porphyrin fluorescence cell lines CFPAC-1 and PANC-1 line H6c7 following incubation with 0.25–1.0 mM 4–48 h. Fluorescence was assessed qualitatively by microscopy quantitatively plate reader flow cytometry. Haem biosynthesis enzymes transporters were...
The aim of this study was to describe short- and long-term outcomes patients who underwent pancreatoduodenectomy (PD) at a typical United Kingdom hepatopancreatobiliary unit.A retrospective analysis all PD with histologically-confirmed pancreatic ductal adenocarcinoma (PDAC), ampullary (AA), or distal cholangiocarcinoma (CC) from September 1st, 2006 May 31st, 2015 carried out. following information obtained: demographics, comorbidities, preoperative investigations, neoadjuvant treatment,...
Over 80% of patients with pancreatic ductal adenocarcinoma (PDAC) are diagnosed at a late stage and locally advanced or concurrent metastases. The aggressive phenotype relative chemo- radiotherapeutic resistance PDAC is thought to be mediated largely by its prominent stroma, which supported an extracellular matrix (ECM). Therefore, we investigated the impact tissue-matched human ECM in driving role promoting chemotherapy resistance. Decellularized pancreata livers were recellularized PANC-1...
Aims and Method A questionnaire was distributed to patients in a psychiatric hospital Birmingham, UK, identify the factors that affect their satisfaction with ward round. Results The completed by 42 (53% response rate). Waiting time only variable be significantly correlated total score of patient satisfaction. Regression analysis also identified diagnosis meeting consultant before first round as significant predictors Clinical Implications Reducing waiting ensuring meets would make...
Sciatic hernias are one of the rarest types hernia and often pose diagnostic difficulty to clinicians. We report a case an 80-year-old lady with sciatic who had falsely negative computed tomography (CT) but was found have colonic on ultrasonography. The authors recommend that for patients in which there is high degree clinical suspicion CT, ultrasonography may be considered as useful imaging modality confirm diagnosis.
Current surveillance strategies for duodenal adenomatosis in familial adenomatous polyposis (FAP) miss malignancies and underestimate cancer risk ampullary disease. This study aimed to evaluate the utility of endoscopic ultrasound (EUS) assessment FAP patients with and/or referred surgical intervention.A retrospective analysis undergoing index EUS between December 2006 May 2015 was performed. Follow-up completed January 2018, including review all procedures interventions (median follow-up 6...
Hyperammonaemia is often seen in the context of decompensated liver disease. It may also be triggered by stressful medical conditions adults with partial enzyme deficiencies urea cycle. Occasionally, non-hepatic causes can result hyperammonaemia severe enough to cause symptoms. The authors report case a 52-year-old Turkish woman who presented acute-on-chronic confusion, drowsiness and lethargy. Laboratory investigations revealed which had an unclear cause. Although first thought secondary...