Ruben Bellotti
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatitis Pathology and Treatment
- Neuroendocrine Tumor Research Advances
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Complement system in diseases
- Palliative Care and End-of-Life Issues
- Cancer Cells and Metastasis
- Transplantation: Methods and Outcomes
- Biliary and Gastrointestinal Fistulas
- Metabolism, Diabetes, and Cancer
- Cancer, Stress, Anesthesia, and Immune Response
- Intestinal Malrotation and Obstruction Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Surgical Treatments
- Organ Transplantation Techniques and Outcomes
- Medical Imaging and Pathology Studies
- Renal cell carcinoma treatment
- Intestinal and Peritoneal Adhesions
- Salivary Gland Tumors Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
Universität Innsbruck
2021-2024
Innsbruck Medical University
2021-2024
University Hospitals Birmingham NHS Foundation Trust
2023
Queen Elizabeth Hospital Birmingham
2023
University of Hull
2023
Objective: The aim of the present study was to compare long-term post-resection oncological outcomes between A-IPMN and PDAC. Summary Background Data: Knowledge long term (e.g recurrence survival data) comparing adenocarcinoma arising from intraductal papillary mucinous neoplasms (A-IPMN) pancreatic ductal (PDAC) is scarce. Methods: Patients undergoing resection (2010-2020) for were identified retrospectively 18 academic centres compared with PDAC patients same time-period. Propensity-score...
Abstract Background The clinical impact of adjuvant chemotherapy after resection for adenocarcinoma arising from intraductal papillary mucinous neoplasia is unclear. aim this study was to identify factors related receipt and its on recurrence survival. Methods This a multicentre retrospective patients undergoing pancreatic between January 2010 December 2020 at 18 centres. Recurrence survival outcomes who did not receive were compared using propensity score matching. Results Of 459 underwent...
Background: Pancreatoduodenectomy with venous resection (PDVR) may be performed to achieve tumour clearance in patients a pancreatic ductal adenocarcinoma (PDAC) involvement. This study aimed evaluate the impact of PDVR on PDAC outcomes. Methods: In total, 435 either R0 status (n = 322) or R1 within superior mesenteric vein groove 113) were extracted from Recurrence After Whipple’s (RAW) dataset. matched 1:2 ratio standard PD patients. Comparisons then made between two groups (surgical...
<h2>Summary</h2> Liver transplantation (LT) was originally described by Starzl as a promising strategy to treat primary malignancies of the liver. Confronted with high recurrence rates, indications drifted towards non-oncologic liver diseases LT finally evolving from high-risk surgery an almost routine surgical procedure. Continuously improving outcomes following and oncological treatment strategies have driven renewed interest in transplant oncology. This is not only reflected constant...
Acinar cell carcinomas (ACC) belong to the exocrine pancreatic malignancies. Due their rarity, there is no consensus regarding treatment strategies for resectable ACC.This a retrospective multicentric study of radically resected pure ACC. Primary endpoints were overall survival (OS) and disease-free (DFS). Further oncologic outcomes related tumor stage therapeutic protocols.59 patients (44 men) with median age 64 years included. The size was 45.0 mm. 61.0% pT3 (n = 36), nodal positivity rate...
Objective: This international multicentre cohort study aims to identify recurrence patterns and treatment of first second in a large patients after pancreatic resection for adenocarcinoma arising from IPMN. Summary Background Data: Recurrence post IPMN are poorly explored. Method: Patients undergoing between January 2010 December 2020 at 18 centres were identified. Survival analysis was performed by the Kaplan-Meier log rank test multivariable logistic regression Cox-Proportional Hazards...
Abstract Background Pancreatoduodenectomy (PD) is associated with significant postoperative morbidity. Surgeons should have a sound understanding of the potential complications for consenting and benchmarking purposes. Furthermore, preoperative identification high-risk patients can guide patient selection potentially allow targeted prehabilitation and/or individualized treatment regimens. Using large multicentre cohort, this study aimed to calculate incidence all PD identify risk factors....
Abstract Background The clinico-oncological outcomes of precursor epithelial subtypes adenocarcinoma arising from intraductal papillary mucinous neoplasms (A-IPMN) are limited to small cohort studies. Differences in recurrence patterns and response adjuvant chemotherapy between A-IPMN unknown. Methods Clincopathological features, long-term patients undergoing pancreatic resection (2010–2020) for were reported 18 academic centres worldwide. Precursor subtype groups compared using uni-...
This study analyzed the prevalence and factors influencing history of chronic anastomotic leakage following low anterior resection for rectal cancer. Furthermore, treatment a persisting presacral sinus impact stoma reversal on outcome were evaluated.The institutional database was scanned all patients with leakage, who primarily treated cancer between January 1995 December 2019. Patients rectovaginal rectovesical fistula or an inadequate follow-up excluded (n = 5). After applying exclusion...
Pancreatoduodenectomy is still hampered by significant morbidity. So far, there no universally accepted technique aimed at minimizing postoperative complications. Herein, we compare three different reconstruction techniques. This a retrospective study of prospectively maintained database including 283 patients operated between January 2010 and December 2020. Three techniques were compared: (1) the Neuhaus-style telescope pancreatojejunostomy, (2) pancreatogastrostomy, (3) modified...
/Objectives: This study aimed to evaluate the frequency, clinical impact, and risk factors of post-pancreatectomy acute pancreatitis (PPAP) after pancreatoduodenectomy (PD) according definition proposed by International Study Group for Pancreatic Surgery (ISGPS). patients undergoing PD between 2010 2021 were retrospectively analyzed. PPAP was defined ISGPS criteria, including elevated serum amylase 48 h concurring alterations on a CT scan. 272 finally included in study. occurred 40 (14.7 %)...