Michael I. Gazes

ORCID: 0000-0003-2401-344X
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About
Contact & Profiles
Research Areas
  • Diabetic Foot Ulcer Assessment and Management
  • Wound Healing and Treatments
  • Tendon Structure and Treatment
  • Peripheral Artery Disease Management
  • Orthopedic Surgery and Rehabilitation
  • Pressure Ulcer Prevention and Management
  • Foot and Ankle Surgery
  • Phagocytosis and Immune Regulation
  • Diagnosis and Treatment of Venous Diseases
  • Bone fractures and treatments
  • Soft tissue tumor case studies
  • Genital Health and Disease
  • Total Knee Arthroplasty Outcomes
  • Nonmelanoma Skin Cancer Studies
  • Erythrocyte Function and Pathophysiology
  • Orthopedic Infections and Treatments
  • Diabetes Management and Education
  • Planarian Biology and Electrostimulation
  • Mesenchymal stem cell research
  • Streptococcal Infections and Treatments
  • Soft tissue tumors and treatment
  • Cancer Diagnosis and Treatment
  • Oral and Maxillofacial Pathology
  • Impact of Light on Environment and Health
  • Laser Applications in Dentistry and Medicine

Yale New Haven Hospital
2015-2024

Yale University
2018-2024

New York College of Podiatric Medicine
2013-2014

Icahn School of Medicine at Mount Sinai
2013

Apoptosis and clearance of apoptotic cells via efferocytosis are evolutionarily conserved processes that drive tissue repair. However, the mechanisms by which recognition regulate repair not fully understood. Here, we use single-cell RNA sequencing to provide a map cellular dynamics during early inflammation in mouse skin wounds. We find pathways receptors elevated fibroblasts immune cells, including resident Lyve1+ macrophages, inflammation. Interestingly, human diabetic foot wounds...

10.7554/elife.86269 article EN cc-by eLife 2023-12-21

Wound repair requires the coordination of multiple cell types including immune cells and tissue resident to coordinate healing return function. Diabetic foot ulceration is a type chronic wound that impacts over 4 million patients in US 7 worldwide (Edmonds et al., 2021). Yet, cellular molecular mechanisms go awry these wounds are not fully understood. Here, by profiling ulcers from non-diabetic (NDFUs) diabetic (DFUs) using single-cell RNA sequencing, we find DFUs display transcription...

10.1101/2023.02.16.528839 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-02-18

Ganglion cysts have been recorded in many areas throughout the body. Intratendinous ganglion foot are very rare. We present case of 51-year-old woman with a recurrent right cyst. Surgical excision revealed cyst tendon sheath extensor digitorum longus. It is important to be aware potential involvement for cysts, as surgeons must prepared perform repairs addition mass excisions if compromised.

10.7547/19-046 article EN Journal of the American Podiatric Medical Association 2020-01-01

Management of diabetes mellitus (DM) involves podiatrists as the primary practitioners engaged in prevention and treatment lower limb pathology. Patients must first possess adequate knowledge to engage effective self-management. A assessment a DM cohort has never before been conducted Ireland. The research objective was determine existence gaps specific areas DM-related between type 2 (T2DM) patients Galway (GW) New York (NY). cross-sectional study compared levels cohorts over 10-week...

10.1177/1534734616638775 article EN The International Journal of Lower Extremity Wounds 2016-03-24

Charcot’s neuroarthropathy complicated by calcaneal osteomyelitis can be difficult to treat. Various surgical techniques describe how manage these conditions. Eggshell-type debridement with application of antibiotic-impregnated bone substitute is a viable option that eliminates infected and allows staged reconstructive surgery. A 50-year-old woman right midfoot presented the cuboid fourth fifth metatarsal bases after resection failed antibiotic therapy. The patient eventually developed...

10.7547/23-092 article EN Journal of the American Podiatric Medical Association 2024-07-01

Partial calcanectomy (PC) can be performed to treat chronic heel ulcers in patients with calcaneal osteomyelitis. Patients undergoing PC often have multiple comorbidities, limited mobility, and face high risk of major limb amputation. This study examined the extent vascular diagnostic testing interventions as well long-term outcomes PC.

10.1177/17085381241247627 article EN Vascular 2024-04-17

Complex soft-tissue injuries consist of difficult traumatic caused by high-energy mechanisms such as motor vehicle accidents, lawnmower injuries, and crush from heavy objects. Many times, because the trauma, there is significant damage to soft tissue underlying bone, leading a complex situation for healing. In this case report, 43-year-old woman presented with extensive degloving injury open fractures forefoot resulting accident. After irrigation debridement, wound closure was achieved using...

10.7547/20-014 article EN Journal of the American Podiatric Medical Association 2022-03-01

Desmoplastic fibroblastomas are benign and uncommon soft-tissue tumors. They typically slow-growing, painless masses found in adult men. Rapidly growing have been previously reported, but more rare. A 56-year-old man presented with a rapidly mass his left foot, which was diagnosed as desmoplastic fibroblastoma after pathologic evaluation. Although many case reports published the dermatology literature, it is important to be aware of this neoplasm avoid confusion other malignant reported...

10.7547/20-097 article EN Journal of the American Podiatric Medical Association 2022-09-01
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